Sulfacil sodium eye drops 20% 10 ml (sulfacetamide)

Release form

Eye drops 20% clear, colorless or slightly colored.

Pharmacological action

Antibacterial agent for topical use in ophthalmology, sulfanilamide derivative. It has a wide range of antimicrobial effects. It has a bacteriostatic effect. The mechanism of action is associated with competitive antagonism with PABA and competitive inhibition of dihydropteroate synthetase, which leads to impaired synthesis of tetrahydrofolate acid, necessary for the synthesis of purines and pyrimidines.

Sulfacetamide is active against gram-positive and gram-negative bacteria (including pathogenic cocci, Escherichia coli), Chlamydia spp., Actinomyces spp.

Pharmacokinetics

When applied topically, it penetrates the tissues and fluids of the eye. It is absorbed into the systemic circulation through the inflamed conjunctiva.

Indications

Purulent corneal ulcers, conjunctivitis, blepharitis, gonorrheal diseases of the eyes in newborns and adults, prevention of blennorrhea in newborns.

Contraindications

Hypersensitivity to sulphacetamide and other sulfa drugs.

Special instructions

Patients with hypersensitivity to furosemide, thiazide diuretics, sulfonylureas or carbonic anhydrase inhibitors may have an increased sensitivity to sulfacetamide.

Composition

1 ml contains:

Active ingredient sulfacetamide 200 mg.

Excipients: sodium thiosulfate hydrochloric acid solution 1 M water for injection

Dosage and administration

Apply 2-3 drops in the lower conjunctival sac of each eye 5-6 times / day.

For the prevention of blennorrhea in newborns, 2 drops of the solution are instilled into the eyes immediately after birth and 2 drops after 2 hours.

Side effects

Local reactions: itching, redness, swelling.

Drug Interactions

Sulfacetamide is not compatible with silver salts when applied topically.

Storage conditions

In the dark place at a temperature of no higher than 8-15 ° C.

Expiration

2 years.

Deystvuyuschee substances

sulfacetamide

Terms and conditions

without prescription

dosage form

eye drops

Indications

Blepharitis, Konayunktivit



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