Skinoklyr 20% 30.0 Cream for external use

Special Price $34.65 Regular Price $35.00
In stock
SKU
FL102015154
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Category

Acne

Scope of the drug

Leather

Release form

Cream

Manufacturer country

Russia

Package quantity, pcs

one

Description

Dosage form

white to yellowish-white opaque homogeneous gel.

Structure

Composition for 100 g of gel:

Active substance: azelaic acid -15.0 g

Excipients: carbomer 980 - 1.0 g, benzoic acid - 0.1 g, disodium edetate dihydrate - 0.1 g, ceramides LS - 0.1 g, isopropyl myrisgate - 1.0 g, polysorbate-20 -1.5 g, propylene glycol - 12.0 g, sodium hydroxide - 0.2 g, water - up to 100.0 g

general description

Acne rash treatment remedy.

Special conditions

The drug is intended for external use only.

Avoid hitting it

on the mucous membrane of the eyes, nose, mouth, as it can cause irritation.

In case of accidental contact of the drug in the eyes, they should be immediately rinsed with running water.

In cases of severe skin irritation in the first weeks of treatment, Skinoclear can be used 1 time / day or the amount of gel applied to the skin can be reduced

short-term drug withdrawal is also possible.

After the symptoms of skin irritation have disappeared, regular use of the drug should be resumed at the recommended dose.

Dermal melasma is insensitive to drug treatment.

A Wood lamp is used for differential diagnostics.

Skinoclear can be used in combination with other acne therapies.

In this case, it is possible to correct the dosage regimen of simultaneously used drugs.

During treatment, it is necessary to protect the skin from the entire spectrum of solar radiation.

Influence on the ability to drive vehicles and work with mechanisms

The drug does not affect driving and engaging in other potentially hazardous activities that require an increased concentration of attention and speed of psychomotor reactions.

Drug interactions

The interaction of the drug with other drugs is still not known.

Pharmacodynamics

Causes a moderate cytostatic effect (by inhibiting the synthesis of cellular proteins), manifested in the normalization of keratinization processes in the wall of the sebaceous follicles has an antimicrobial effect (primarily against Propionibacterium acnes and Staphylococcus epidermidis) both on the surface of the skin and in the sebaceous glands, as well as anti-inflammatory effect (reducing the metabolism of neutrophilic granulocytes and their production of free radical oxygen species - important factors in maintaining the inflammatory process).

With prolonged use of the drug, resistance of microorganisms is not formed.

Azelaic acid dose-dependently inhibits the growth and viability of abnormal melanocytes.

The therapeutic effect in hyperpigmentation (melasma) is due to inhibition of DNA synthesis and / or suppression of cellular respiration of abnormal melanocytes.

Pharmokinetics

Suction

After application to the skin, azelaic acid penetrates the epidermis and dermis.

After applying 1 g of azelaic acid to the skin (which corresponds to 5 g of gel), about 3.6% of the dose is absorbed into the systemic circulation.

Withdrawal

Part of the absorbed azelaic acid is excreted by the kidneys unchanged, and part in the form of dicarboxylic acids (C5, C7), formed from azelaic acid as a result of beta-oxidation.

Indications

- Common acne (acne vulgaris)

-Rosacea.

Contraindications

- Hypersensitivity to azelaic acid and other components of the drug

-Children under 12 years old.

APPLICATION DURING PREGNANCY AND DURING BREASTFEEDING

During pregnancy and during breastfeeding, the drug should be used only if the intended benefit to the mother outweighs the possible risk to the fetus and child.

Avoid applying the gel to the breast area before feeding

Overdose

Currently, no cases of overdose have been described.

Side effects

Adverse reactions are presented depending on the frequency of development: very often (1/10 g)

often (> 1/100 to < 1/10)

infrequently (> 1/1000 to < 1/100), rarely (> 1/10000 to < 1/1000), very rare (< 1/10 000), unknown (cannot be estimated based on available data).

Disorders of the skin and subcutaneous fat:

Uncommon: seborrhea, acne, skin depigmentation

Very often: itching, burning, erythema at the site of application

Often: peeling, dry skin, irritation

Rarely: cheilitis.

General disorders and disorders at the injection site:

Uncommon: paresthesia, dermatitis, discomfort, edema at the site of application

Rarely: vesicular eruptions, eczema, warmth, rash at the site of application

Often: pain at the site of application.

Immune system disorders: Rarely: allergic reaction, worsening of bronchial asthma.

As a rule, local skin reactions go away on their own during treatment.

If any of the side effects indicated in the instructions are aggravated, or any other side effects not indicated in the instructions are noted, you should immediately inform your doctor.

Dosage

20% x 30g

Indications

Common acne (acne vulgaris)

Melasma-type hyperpigmentation such as chloasma.

INN / Active ingredient

Azelaic acid

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

Contraindications

Hypersensitivity to azelaic acid and other components of the drug

Children up to age 12.

Specifications

Category

Acne

Scope of the drug

Leather

Release form

Cream

Manufacturer country

Russia

Package quantity, pcs

one

Scope of application

Dermatology

Vacation conditions

Without recipe

Brand name

Skincleer

The amount of the dosage form in the primary package

30 g

Primary packaging type

Tuba

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Acne rash treatment

Anatomical and therapeutic characteristics

D10AX03 Azelanic acid

Dosage form

Cream for external use

Dosage (volume) of the substance in the preparation

azelaic acid - 20.00 g

Expiration date in days

1095

Package weight, g

thirty

Information on technical characteristics, delivery set, country of manufacture

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