Rinostop Extra nasal drops, bottle-cap, 0.025%, 10ml, # 1

pharmachologic effect

Pharmacotherapeutic group:

Decongestant (alpha-adrenergic agonist)

ATX:

S.01.GA04 Oxymetazoline

Pharmacodynamics:

The remedy for the common cold Rinostop Extra (oxymetazoline) has a vasoconstrictor effect.

When applied topically to the inflamed mucous membrane of the nasal cavity, it reduces its swelling, nasal congestion, nasal discharge, eliminating the symptoms of rhinitis.

Restores nasal breathing.

Elimination of edema of the nasal mucosa helps to restore aeration of the paranasal sinuses, middle ear cavity, which prevents the development of bacterial complications (sinusitis, sinusitis, otitis media).

With local intranasal application in therapeutic concentrations, it does not irritate and does not cause hyperemia of the nasal mucosa.

The drug begins to act quickly (within a few minutes).

The duration of action of Rinostop Extra is up to 12 hours.

Pharmacokinetics:

With local intranasal application, the drug does not have a systemic effect.

The half-life of oxymetazoline with its intranasal administration is 35 hours. 2.1% of oxymetazoline is excreted by the kidneys and about 1.1% through the intestine.

Indications

- Treatment of acute respiratory diseases accompanied by rhinitis (runny nose)

- allergic rhinitis

- vasomotor rhinitis

- to facilitate the outflow of discharge from the paranasal sinuses with sinusitis, eustachitis, otitis media

- to eliminate edema before diagnostic manipulations in the nasal passages.

Contraindications

- Atrophic rhinitis

- hypersensitivity to drug components

- angle-closure glaucoma

- condition after transsphenoidal hypophysectomy

- surgical interventions on the dura mater (in history)

- children under 1 year old - for drops of 0.025%

- children under 6 years old - for drops of 0.05%.

You should adhere to the recommended concentrations of the drug intended for different age categories (see methods of application).

Carefully:

In patients taking monoamine oxidase inhibitors (MAO) and other drugs that increase blood pressure (including in the period up to 14 days after their withdrawal) in patients with concomitant severe forms of cardiovascular diseases (arterial hypertension, ischemic heart disease, chronic heart failure, tachycardia, arrhythmias) with hyperthyroidism, diabetes mellitus, pheochromocytoma, prostatic hyperplasia with clinical manifestations (urinary retention), severe atherosclerosis, porphyria, during pregnancy and during breastfeeding, with increased intraocular pressure, chronic renal failure, in patients taking tricyclic antidepressants, and bromo-depressants as well as other drugs that increase blood pressure.

If you have one or more of the above diseases and conditions, you should consult your doctor before taking the drug.

Side effects

Burning or dryness of the mucous membranes of the nasal cavity, dryness of the mucous membranes of the mouth and throat

sneezing

an increase in the volume of secretions from the nose

nose bleed

after the effect of the drug has passed, a feeling of nasal congestion (reactive hyperemia).

Side effects due to the systemic action of the drug (if the solution is accidentally taken orally): increased blood pressure, headache,

dizziness, palpitations, tachycardia, anxiety, anxiety, fatigue, drowsiness, sedation, irritability, sleep disturbance (in children), nausea, insomnia, exanthema, hallucinations, Quincke's edema, itching, convulsions, respiratory arrest (in infants).

Visual impairment (by eye contact).

Long-term continuous use of vasoconstrictor drugs can lead to tachyphylaxis, atrophy of the nasal mucosa and recurrent edema of the nasal mucosa

Name ENG

RHINOSTOP EXTRA

ATX code

oxymetazoline

Dosage

0.25 mg

Structure

Composition for 1 ml: Active ingredient: oxymetazoline hydrochloride 0.25 mg Excipients: citric acid monohydrate 0.6093 mg sodium citrate dihydrate 3.8230 mg glycerol 24.3480 mg benzalkonium chloride 50% solution 0.1000 mg purified water to 1 ml

Indications

Treatment of acute respiratory diseases accompanied by rhinitis (runny nose)

- allergic rhinitis

- vasomotor rhinitis

- to facilitate the outflow of discharge from the paranasal sinuses with sinusitis, eustachitis, otitis media

- to eliminate edema before diagnostic manipulations in the nasal passages.

Contraindications

Atrophic rhinitis - hypersensitivity to the components of the drug - angle-closure glaucoma - condition after transsphenoidal hypophysectomy - surgical interventions on the dura mater (in history) - children under 1 year old - for drops of 0.025% You should adhere to the recommended concentrations of the drug intended for different age categories (see methods of application). With care: In patients taking monoamine oxidase (MAO) inhibitors and other drugs that increase blood pressure (including in the period up to 14 days after their cancellation) in patients with concomitant severe forms of cardiovascular diseases (arterial hypertension, ischemic heart disease, chronic heart failure, tachycardia, arrhythmias) with hyperthyroidism, diabetes mellitus, pheochromocytoma,hyperplasia of the prostate gland with clinical manifestations (urinary retention), severe atherosclerosis, porphyria, during pregnancy and during breastfeeding, with increased intraocular pressure, chronic renal failure, in patients taking tricyclic antidepressants and bromocriptine, as well as other drugs that increase blood pressure ... If you have one or more of the above diseases and conditions, you should consult your doctor before taking the drug.as well as other drugs that increase blood pressure. If you have one or more of the above diseases and conditions, then before starting to take the drug, you should consult your doctor.as well as other drugs that increase blood pressure. If you have one or more of the above diseases and conditions, you should consult your doctor before taking the drug.

Storage conditions and periods

Store at a temperature not exceeding 25 В° C.

Keep out of the reach of children.

Store in original packaging.

Shelf life 3 years.

Do not use the drug after the expiration date.

INN / Active ingredient

oxymetazoline hydrochloride

Specifications

Category

Runny nose

Scope of the medicinal product

Ear, Throat, Nose

Release form

Drops

Minimum age from

6 years

Way of introduction

Nasally

Vacation conditions

Without recipe

Volume, ml.

10 ml

Brand name

OTCPharm

Dosage form

Nasal spray

Dosage (volume) of the substance in the preparation

0.25 mg

Expiration date in days

1095

The target audience

Children

Package weight, g

ten

Mode of application

:

Intranasal. < br> < br> Adults and children over 6 years old: - apply 1 - 2 drops of 0.05% solution in each nasal passage 2-3 times a day. < br> < br> Children from 1 year to 6 years: apply - 1 - 2 drops of 0.025% solution in each nasal passage 2-3 times a day. < br> < br> Children under one year old: children under 4 weeks old - 1 drop of 0.01% solution in each nasal passage 2-3 times a day.

From the 5th week of life to 1 year - 1-2 drops in each nasal passage 2-3 times a day. < br> < br> In the recommended dose, without consulting a doctor, use no more than 5-7 days.

If symptoms worsen or do not improve within 3 days, you should consult your doctor

Information on technical characteristics, delivery set, country of manufacture