Piroxicam capsules 10 mg, 20 pcs. (Piroxicam)

Release form

Capsules.

Packing

In a package of 20 pieces.

Pharmacological action

Piroxicam is a non-steroidal anti-inflammatory and anti-rheumatic agent. It has anti-inflammatory, analgesic and antipyretic effects. It is used for rheumatic diseases, pain and joint syndrome.

Indications

Inflammatory and degenerative diseases of the musculoskeletal system: rheumatoid and gouty arthritis, rheumatism, ankylosing spondylitis (ankylosing spondylitis), osteoarthritis. Pain syndrome: sciatica, tendovaginitis, bursitis, arthralgia, neuralgia, myalgia, sciatica, post-traumatic and postoperative pain syndrome, accompanied by inflammation, algodismenorea. Feverish syndrome with colds and infectious diseases.

Contraindications

Hypersensitivity, erosive and ulcerative lesions of the gastrointestinal tract (acute stage), aspirin asthma, hepatic and / or renal failure, bleeding disorders (including hemophilia, lengthening of bleeding time, tendency to bleeding, hemorrhagic age) (up to 14 years), age over 65 years, pregnancy, lactation for rectal administration - proctitis, anorectal bleeding.

Use during pregnancy and lactation

Piroxicam is contraindicated in pregnancy and lactation.

Composition

1 capsule contains: piroxicam 10 mg.

Excipients: cellulose powder, sodium carboxymethyl starch (sodium starch glycolate), potato starch, sodium lauryl sulfate, magnesium stearate, gelatin, titanium dioxide or gelatin, titanium dioxide, blue patented dye.

Dosage and Administration

Inside. With rheumatoid arthritis, osteoarthritis and ankylosing spondylitis - 10-30 mg / day in 1 dose, for a long time.

In acute diseases of skeletal muscle - 40 mg / day in one or more doses for 2 days, in the next 7-10 days - 20 mg / day.

In the treatment of an attack of gout, the initial dose is 40 mg, once, in the first 2 days, then for 4-6 days - 40 mg once or 20 mg 2 times a day.

With algodismenorrhea, treatment should be started when the first symptoms appear at an initial dose of 40 mg / day in 1 or more doses for 2 days. In the next 1-3 days - 20 mg in 1 dose.

In juvenile rheumatoid arthritis is prescribed once a day: for children over 14 years old weighing more than 46 kg - 20 mg / day.

Side effects of the

Digestive system: pain and discomfort in the abdomen (including epigastrium), flatulence, nausea, constipation, diarrhea, peptic ulcer, bleeding from the gastrointestinal tract, anorexia, vomiting, dyspepsia, stomatitis, glossitis, glossitis, glossitis, hepatitis.

From the side of the central nervous system: dizziness, headache, increased appetite, sedation, drowsiness, amnesia, anxiety, depression, anxiety, hallucinations, insomnia, unusual dreams, nervousness, paresthesia, personality change, tremor, akathisia.

On the part of the sensory organs: tinnitus, vertigo, deafness, blurred vision, irritation or swelling of the eyes.

Laboratory indicators: increased activity of “liver” enzymes (LDH, alkaline phosphatase, transaminases), increased concentration of urea nitrogen, hypercreatininemia, decreased Hb and hematocrit, hypoproteinemia, thrombocytopenia, leukopenia, anemia (including aplastic and hemolytic), hypoglycemia, detection of antinuclear antibodies.

From the CCC side: increased blood pressure, tachycardia, palpitations, “flushing” of blood to the skin.

From the skin: rash (including petechial), purpura, including thrombocytopenic, ecchymosis, pruritus, onycholysis, alopecia, photosensitization, exfoliative dermatitis, erythema multiforme, Lyell's syndrome, Stevens-Johnson syndrome, vesiculo-bullous reactions.

From the genitourinary system: edema, dysuria, frequent urination, hematuria, oliguria, menorrhagia.

From the respiratory system: nosebleeds, shortness of breath.

Other: chest pain, thirst, chills, excessive sweating, increased or decreased body weight.

Drug Interaction

Displays from communication with the blood proteins of the drugs, decreases the effectiveness of antihypertensive drugs (due to the delay of Na +, K + and water in the body), increases the concentration of phenytoin and Li + preparations. Increases risk of hyperkalemia when combined with potassium-sparing diuretics and K + donors, risk of ulceration of the gastrointestinal mucosa - with ACS. ASA reduces the concentration of piroxicam in the serum. In combination with anticoagulants, it reduces the ability of platelets to aggregate (bleeding risk). Myelotoxic drugs increase the manifestations of hematotoxicity of the drug.

Overdose

Symptoms: nausea, vomiting (at high doses - bloody), mellitus, minor episodes, tinnitus, clonic and tonic convulsions, coma, hemorrhagic diathesis, agranulocytosis, aplastic acne, aplastic, measles or typhoid rashes in predisposed patients - toxic-allergic shock.

Treatment: Conducted according to generally accepted principles of clinical toxicology.

Storage conditions

The drug should be stored in a dark place at a temperature of 15 ° to 25 ° C.

Expiration

3 years.

Deystvuyuschee substances

piroxicam



drugstore terms and conditions Prescription

drug vennaya form

capsule dosage form



Sofarma Bolgaria



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