Nutriflex 48/150 lipid infusion emulsion 2000 ml containers, 5 pcs. (amino acids for parenteral POWER)

Release form

Infusion solution

Packaging

Container 2000 ml.

Pharmacological action

Nutriflex 48/150 - a means for parenteral nutrition.

Nutriflex contains in one bag chamber amino acids that are a substrate for protein synthesis and minerals necessary to maintain water-electrolyte and acid-base balance, and in the second chamber, a glucose solution with electrolyte solutions.

Indications

Used for parenteral nutrition to cover the daily needs of patients for energy, amino acids, electrolytes and fluids in patients with moderate to severe catabolism, in cases where enteral nutrition is impossible, insufficient or contraindicated.

Contraindications

impaired amino acid metabolism

hyperkalemia

hyponatremia

impaired metabolism (for example, with diabetes mellitus)

coma of unclear etiology

hyperglycemic / unrelated insulin heart failure 6 years. up to 2 years

individual intolerance to one of the components of the mixture.

General for parenteral nutrition:

severe circulatory disorders (collapse and shock)

severe tissue hypoxia

hyperhydration

disturbances of water-electrolyte balance

pulmonary edema

decompensated heart failure.

Composition

Emulsion for infusion - solutions of amino acids and glucose with electrolytes: clear, pale yellow or yellow solutions fat emulsion: oil-in-water emulsion of milky white color.

1 l

isoleucine 2.26 g

leucine 3.01 g

lysine (in the form of hydrochloride) 2.18 g

methionine 1.88 g

phenylalanine 3.37 g

threonine 1.74 g

tryptophan 0.54 mg srldgrrd rrd 2.5 srdlrd srdlrd 1.58 g

alanine 4.66 g

proline 3.26 g

aspartic acid 1.44 g

glutamic acid 3.37 g

serine 2.88 g

sodium hydroxide 0.781 g

sodium chloride 0.402 mg

sodium dihydrogen phosphate dihydrate 0.2 g sidl sodium sulfide dihydrate phosphate sulphate g

magnesium acetate tetrahydrate 0.686 g

calcium chloride dihydrate 0.47 g

zinc acetate dihydrate 5. 264 mg

medium chain triglycerides 20 g

soybeans oil 20 g

dextrose (in the form of a monohydrate) 120 g

The emulsion after mixing the contents of the container chambers contains:

amino acids 38.4 g

carbohydrates 120 g srdlrd kp 40 g

fat value:

amino acids 640 kJ (152 kcal)

carbohydrates 2008 kJ (480 kcal)

fats 1592 kJ (380 kcal)

non-protein energy value 3600 kJ (860 kcal)

total energy value 4240 kJ (

Concentration: 1012 kcal

sodium 40 mmol

potassium 28 mmol

calcium 3.2 mM Magnesium 3.2 mmol



0.024 mmol

zinc chlorides acetates

36 mmol 36 mmol 12 mmol

phosphates

Excipients: citric acid monohydrate 0-0.336 g, glycerol 5 g, egg lecithin 2.4 g, sodium oleate 0.06 g, water d / i - up to 1000 ml.

Osmolality: 1540 mOsm / kg.

pH: 5.0 - 6.0.

Dosage and Administration

Nutriflex 48/150 is for administration only to the central veins.

Nutriflex 48/150 preparation procedure for use:

Nutriflex 48/150 is a two-chamber bag, the compartments of which are separated by a special seam. One chamber is filled with a solution of amino acids and electrolytes, and the other with a solution of dextrose and electrolytes. Immediately before starting parenteral administration, solutions of amino acids, glucose and electrolytes should be mixed. For this it is necessary: ​​

to take out the two-chamber bag from the protective packaging, to open

and lay it out on a flat surface (on the table),

to break the separation seam by pressing with two hands on one of the chambers of the bag, take

in your hands and mix the contents of both chambers, moving the right and left parts of the bag up and down.

After (the solution is ready for use. At the end of the infusion, the bag is discarded.

If necessary, lipid emulsions can be added to Nutriflex 48/150 by adding them to the finished solution through a special port located on top of the bag. If necessary, add other ingredients to the finished solution must use the additional port located below.All ingredients must be added in compliance with aseptic rules and taking into account their compatibility with each other.

Doses:

are selected according to ii individual needs. The maximum daily dose of 40 ml / kg m. t. / day, which corresponds to 1.92 g of amino acids / kg bw / day and 6 g of glucose / kg bw / day.

Speed ​​of administration:

The maximum infusion rate is 2 ml / kg bw / h, which corresponds to 0.096 g of amino acids / kg bw / h and 0.3 g glucose / kg bw / h.

Duration of use:

There are no restrictions on the duration of use of the drug.

Precautions for use of the drug:

In patients with increased osmolarity of blood plasma, heart failure, liver and / or renal failure. For patients with heart, liver and kidney failure, the dosage and regimen of the drug are set individually.

Side effects

Side effects are very rare. Upon termination of therapy, they are rapidly reversible.

The introduction of the drug can lead to allergic reactions, chills, nausea, and vomiting.

Due to the high osmolarity of the solution, in some cases, signs of increased diuresis may appear.

In such cases, the drug should be discontinued and resumed later at a lower rate of infusion.

In case of side effects that are not described in the instructions, patients should report them to their doctor.

Storage conditions

In the dark place at a temperature of no higher than 25 ° C.

Shelf life

2 years

active substance

amino acids for parenteral nutrition

Conditions of release from drugstores

Prescription

lekarstvennaja form

Solution for infusion

.B.



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