Nurofast Forte tablets coated.pl.ob. 400 mg 20 pcs. (Ibuprofen)

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Indications

NurofastВ® Forte is used for headache, migraine, toothache, painful menstruation, neuralgia, back pain, muscle pain, rheumatic pain and joint pain

, as well as for fever with flu and colds. Buy Nurofast Forte tablets coated.pl.ob. 400 mg 20 pcs. (Ibuprofen) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Indications

NurofastВ® Forte is used for headache, migraine, toothache, painful menstruation, neuralgia, back pain, muscle pain, rheumatic pain and joint pain

, as well as for fever with flu and colds.

Contraindications

Hypersensitivity to ibuprofen or any of the components that make up the drug.

Complete or incomplete combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance to acetylsalicylic acid or other NSAIDs (including a history of).

Erosive and ulcerative diseases of the gastrointestinal tract (including gastric and duodenal ulcers, Crohn's disease, ulcerative colitis) or ulcerative bleeding in the active phase or in the anamnesis (two or more confirmed episodes of peptic ulcer or ulcer bleeding).

History of bleeding or perforation of a gastrointestinal ulcer provoked by the use of NSAIDs.

Severe heart failure (NYHA Class IV - Classification of the New York Association of Cardiology).

Severe liver failure or liver disease in the active phase.

Severe renal failure (creatinine clearance <30 ml / min), confirmed hyperkalemia.

Decompensated heart failure period after coronary artery bypass grafting.

Cerebrovascular or other bleeding.

Hemophilia and other bleeding disorders (including hypocoagulation), hemorrhagic diathesis.

Pregnancy (III trimester).

Children under 12 years old.

Caution

If you have the conditions mentioned in this section, you should consult your doctor before using the drug.

Concomitant use of other NSAIDs, a history of a single episode of gastric and duodenal ulcer or gastric ulcer, gastritis, enteritis, colitis, the presence of Helicobacter pylori infection, ulcerative colitis bronchial asthma or an allergic disease in the acute stage or in the anamnesis - it is possible to develop bronchospasm systemic lupus erythematosus or mixed connective tissue disease (Sharpe's syndrome) - increased risk of aseptic meningitis chickenpox renal failure, including dehydration (creatinine clearance less than 30- 60 ml / min), nephrotic syndrome, liver failure, liver cirrhosis with portal hypertension, hyperbilirubinemia, arterial hypertension and / or heart failure Th, cerebrovascular disease, blood disease of unknown etiology (leucopenia and anemia), severe somatic disorders, dyslipidemia / hyperlipidemia, diabetes mellitus, peripheral vascular disease, smoking and frequent use of alcohol, the simultaneous use of drugs, which may increase the risk of ulcers or bleeding, in particular, oral glucocorticosteroids (including prednisone), anticoagulants (including warfarin), selective serotonin reuptake inhibitors (including citalopram, fluoxetine, paroxetine, sertraline) or antiplatelet agents (in including acetylsalicylic acid, clopidogrel), pregnancy I-II trimester, breastfeeding, old age.

Special instructions

It is recommended that you take the drug as soon as possible and in the minimum effective dose necessary to eliminate the symptoms. If you need to take the drug for more than 10 days, you must consult a doctor.

In patients with bronchial asthma or an allergic disease in the acute stage, and also in patients with a history of bronchial asthma / allergic disease, the drug can provoke bronchospasm. The use of the drug in patients with systemic lupus erythematosus or mixed connective tissue disease is associated with an increased risk of developing aseptic meningitis.

During prolonged treatment, monitoring of the peripheral blood picture and the functional state of the liver and kidneys is necessary. When symptoms of gastropathy appear, careful monitoring is indicated, including esophagogastroduodenoscopy, a general blood test (determination of hemoglobin), fecal occult blood analysis. If it is necessary to determine 17-ketosteroids, the drug should be discontinued 48 hours before the study. During treatment, ethanol is not recommended.

Patients with renal failure should consult a doctor before using the drug, since there is a risk of impaired renal function.

Patients with hypertension, including a history of and / or chronic heart failure, should consult a doctor before using the drug, since the drug can cause fluid retention, increased blood pressure and swelling.

Patients with uncontrolled arterial hypertension, NYHA class II-III congestive heart failure, coronary heart disease, peripheral artery disease and / or cerebrovascular disease should be prescribed ibuprofen only after a careful assessment of the benefit-risk ratio, and the use of high doses of ibuprofen should be avoided ( 2400 mg / day).

NSAIDs in patients with chickenpox may be associated with an increased risk of developing severe purulent complications of infectious and inflammatory diseases of the skin and subcutaneous fat (e.g., necrotizing fasciitis). In this regard, it is recommended to avoid the use of the drug for chickenpox.

Information for women planning a pregnancy: the drug suppresses cyclooxygenase and prostaglandin synthesis, affects ovulation, disrupting female reproductive function (reversible after canceling treatment).

Effects on ability to drive vehicles and mechanisms

Patients with dizziness, drowsiness, lethargy, or visual impairment while taking ibuprofen should avoid driving or operating machinery.

Composition

1 film-coated tablet contains:

active ingredient:

ibuprofen - 400 mg

excipients:

sodium croscarmellose,

sodium citrate dihydrate, srdlkld sodium magnesium sulfide sulfide (sodium sulfide sulfide)

stearic acid

coating aids:

Opadry II 85F48105 white (polyvinyl alcohol, macrogol, talc, titanium dioxide).

Dosage and administration

For oral administration. Patients with increased gastric sensitivity are recommended to take the drug with meals.

For short-term use only. Read the instructions carefully before taking the drug.

Adults and children 12 years of age and inside, take 1 tablet (400 mg) up to 3 times a day.

Tablets should be washed down with water.

The interval between taking the tablets should be at least 4 hours.

The maximum daily intake for adults is 1200 mg (3 tablets).

The maximum daily dose for children from 12 to 18 years is 800 mg (2 tablets).

If, after taking the drug for 2–3 days, symptoms persist or intensify, stop treatment and consult a doctor.

Side effects

The risk of side effects can be minimized if you take the drug in a short course, at the minimum effective dose needed to eliminate the symptoms.

Elderly people have an increased frequency of adverse reactions with NSAIDs, especially gastrointestinal bleeding and perforations, in some cases fatal.

Side effects are predominantly dose dependent.

The following adverse reactions have been observed with short-term use of ibuprofen in doses not exceeding 1200 mg / day (6 tablets).

In the treatment of chronic conditions and with prolonged use, other adverse reactions may occur.

The frequency of adverse reactions was estimated based on the following criteria: very frequent ( 1/10), frequent (from 1/100 to <1/10), infrequent (from 1/1000 to <1/100), rare (from 1/10000 to <1/1000), very rare (1/10000), the frequency is unknown (there is not enough data to estimate the frequency).

Disorders of the blood and lymphatic system

· Very rare: hematopoiesis (anemia, leukopenia, aplastic anemia, hemolytic anemia, thrombocytopenia, pancytopenia, agranulocytosis). The first symptoms of these disorders are fever, sore throat, superficial oral ulcers, flu-like symptoms, severe weakness, nosebleeds, and subcutaneous hemorrhages, bleeding, and bruising of unknown etiology.

Immune system disorders

· Infrequent: hypersensitivity reactions - non-specific allergic reactions and anaphylactic reactions, reactions from the respiratory tract (bronchial asthma, including exacerbation, bronchospasm, shortness of breath, dyspnea), skin reactions (itching, urticaria, purpura , Quincke's edema, exfoliative and bullous dermatoses, including toxic epidermal necrolysis (Lyell syndrome), Stevens-Johnson syndrome, erythema multiforme), allergic rhinitis, eosinophilia.

· Very rare: severe hypersensitivity reactions, including swelling of the face, tongue and larynx, shortness of breath, tachycardia, arterial hypotension (anaphylaxis, Quincke's edema, or severe anaphylactic shock).

Gastrointestinal disorders

· Infrequent: abdominal pain, nausea, dyspepsia (including heartburn, bloating).

· Rare: diarrhea, flatulence, constipation, vomiting.

· Very rare: peptic ulcer, perforation or gastrointestinal bleeding, melena, bloody vomiting, in some cases fatal, especially in elderly patients, ulcerative stomatitis, gastritis.

· Unknown frequency: exacerbation of colitis and Crohn's disease.

Violation of the liver and biliary tract

· Very rare: impaired liver function, increased activity of “liver” transaminases, hepatitis and jaundice.

Violation of the kidneys and urinary tract

· Very rare: acute renal failure (compensated and decompensated) especially with prolonged use, combined with an increase in the concentration of urea in the blood plasma and the appearance of edema, hematuria and proteinuria, nephritic syndrome, nephrotic syndrome, papillary necrosis, interstitial nephritis, cystitis.

Disorders of the nervous system

· Infrequent: headache.

· Very rare: aseptic meningitis.

Cardiovascular disorders

· Frequency unknown: heart failure, peripheral edema, prolonged use increases the risk of thrombotic complications (eg, myocardial infarction), increased blood pressure.

Violation of the respiratory system and mediastinal organs

· Frequency unknown: bronchial asthma, bronchospasm, shortness of breath.

Laboratory indicators

· hematocrit or hemoglobin (may decrease)

· bleeding time (may increase)

· plasma glucose concentration (may decrease)

· creatinine clearance (may decrease)

· plasma creatinine concentration (may increase) activity of hepatic transaminases (may increase)

If side effects occur, you should stop taking the drug and consult a doctor.

Overdose

In children, overdose symptoms may occur after taking a dose in excess of 400 mg / kg body weight.

In adults, the dose-dependent effect of an overdose is less pronounced. The half-life of the drug with an overdose is 1.5-3 hours.

Symptoms: nausea, vomiting, epigastric pain or, less commonly, diarrhea, tinnitus, headache, and gastrointestinal bleeding. In more severe cases, manifestations from the central nervous system are observed: drowsiness, rarely - agitation, convulsions, disorientation, coma.

In cases of severe poisoning, metabolic acidosis and an increase in prothrombin time, renal failure, damage to liver tissue, decreased blood pressure, respiratory depression and cyanosis can develop. In patients with bronchial asthma, an exacerbation of this disease is possible.

Treatment: symptomatic, with mandatory airway management, ECG monitoring and basic vital signs up to the normalization of the patient's condition. Oral administration of activated charcoal or gastric lavage within 1 hour after taking a potentially toxic dose of ibuprofen is recommended.

If ibuprofen has already been absorbed, alkaline drink may be prescribed in order to excrete the acid derivative of ibuprofen by the kidneys, forced diuresis. Frequent or prolonged seizures should be stopped by the intravenous administration of diazepam or lorazepam.

When bronchial asthma worsens, the use of bronchodilators is recommended.

Storage conditions

Store at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Shelf life

3 years.

Active ingredient

ibuprofen

Conditions of supply of

pharmacies without a prescription

lekarstvennaja form

tablets



Nurofast Forte tablets coated.pl.ob. 400 mg 20 pcs. (Ibuprofen) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Nurofast Forte tablets coated.pl.ob. 400 mg 20 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.

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