Mikospor ointment in a set of ointment 10 g, plasters, nail file (Bifonazole)

Latin name

Mycospor

Release form

Ointment + dispenser + adhesive + plaster

Packaging

In an aluminum tube 10 g of ointment. In the package 1 tube complete with a scraper, 15 strips of waterproof patch and dispenser.

Pharmacological action

Mikospor is a broad-spectrum antifungal drug derived from imidazole. The mechanism of action is associated with a violation of the biosynthesis of ergosterol, which is part of the cell membrane of the fungus, at two different levels, which distinguishes it from other antifungal drugs and other azole derivatives. Such a double action leads to structural and functional damage to the cytoplasmic membrane of fungi.

Active against: Dermatophytes.

Yeast and mold.

Malassezia furfur.

Corynebacterium minutissimum.

Urea, which is part of the ointment, has a keratoplastic function, softening the keratin of an infected nail and increasing the penetration depth of bifonazole. This combination enhances the antimycotic effect of the drug.

A full fungicidal effect is achieved with a concentration of bifonazole of 5 μg / ml and a duration of exposure of 6 hours.

With a yeast infection (Candida species) at a concentration of 1-4 μg / ml, a mainly fungistatic effect is noted for the fungicidal effect, a concentration of bifonazole of 20 μg / ml is required. With the defeat of Corynebacterium, the concentration of bifonazole should be 0.5-2 μg / ml.

Resistant strains of fungi are very rare. Studies have not confirmed the development of secondary resistance in primary sensitive strains.

Indications

Dermatophytosis (including microsporia, trichophytosis, rubrophytia)

candidiasis of the skin, nail ridges, nails, genitalia

multicolor lichen

erythrasma

interdigital opra toe

Contraindications

hypersensitivity, infancy (use is possible only under the supervision of a doctor).

Use during pregnancy and lactation

The drug is contraindicated for use in the first trimester of pregnancy.

Composition of

1 g of ointment contains:

Active ingredients: bifonazole 10 mg urea 400 mg

Excipients: white beeswax, white petrolatum, lanolin.

Dosage and administration

Ointment is applied to the infected nail 1 time per day in an amount sufficient to cover the entire surface of the nail with a thin layer. Then the treated nail is sealed with a plaster and left under the dressing for 24 hours, after which the dressing is changed. After removing the patch, the finger (or arm or leg) is immersed in warm water for about 10 minutes and then the softened part of the infected nail is carefully removed with a scraper. Thus treated nails are thoroughly dried, the ointment is applied again and glued with a plaster. Ointment of the skin adjacent to the nail should not be. If signs of irritation appear, the skin around the nail can be treated with zinc paste before gluing the patch.

Treatment should be carried out carefully, changing dressings every day, and continue until the softened nail plate infected with the fungus ceases to be removed by the scraper and the nail bed becomes smooth. This usually takes 7-14 days, depending on the degree of infection and the thickness of the nail.

Ointment Mikospor acts only on an infected nail plate, without affecting healthy areas. It is necessary to monitor the condition of the nail during therapy.

Patient should be informed that after removal of the affected nail plate (i.e. after 7-14 days of therapy), you should definitely consult a doctor.

For the final antifungal therapy, Mikospor cream is used once a day for 4 weeks.

Side effects

Slight redness and irritation of the skin, burning local reactions along the edges or on the bed of the nail (irritation, redness, maceration, peeling, contact dermatitis) allergic reactions.

Storage Conditions

The product should be stored at a temperature not exceeding 30 ° C.

Deystvuyuschee substances

BIFONAZOLE

Form of Treatment

mazy



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