Mezim Forte tablets p / o N80

Release form

Film-coated tablets.

Packaging

80 pcs.

pharmachologic effect

Pharmacodynamics

Pancreatin is a powder from the pancreas of pigs.

Pancreatic enzymes that are part of pancreatin have proteolytic, amylolytic and lipolytic effects and promote the breakdown of proteins, fats, carbohydrates, improve the functional state of the gastrointestinal tract, and normalize digestion processes.

Pharmacokinetics

Mezim tablets are coated with an acid-resistant coating, which does not dissolve under the action of hydrochloric acid in the stomach and, thus, protects the enzymes contained in the preparation from inactivation.

The dissolution of the shell and the release of enzymes occurs at pH values ��close to neutral or slightly alkaline.

Indications

Lack of exocrine pancreatic function (chronic pancreatitis, cystic fibrosis)

chronic inflammatory-dystrophic diseases of the stomach, intestines, liver, gall bladder.

Conditions after resection or irradiation of these organs, accompanied by impaired digestion of poverty, flatulence, diarrhea (as part of combination therapy)

to improve the digestion of food in patients with normal gastrointestinal tract function in case of inaccuracies in nutrition

preparation for X-ray and ultrasound examination of the abdominal organs.

Contraindications

Hypersensitivity to drug components

acute pancreatitis or chronic pancreatitis in the acute stage.

Nevertheless, the appointment is acceptable in the phase of damping exacerbation with the expansion of the diet, if there are signs of indigestion

hereditary galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome

children's age up to 3 years (for this dosage form).

Application during pregnancy and lactation

The safety of using pancreatin during pregnancy has not been studied enough.

Application is possible in cases where the expected benefit to the mother outweighs the potential risk to the fetus.

special instructions

In case of acute pancreatitis or exacerbation of chronic pancreatitis (at the stage of exacerbation of the exacerbation), during a restorative diet, it is advisable to prescribe Mezim forte against the background of existing or remaining in the future pancreatic insufficiency.

Mezim forte, taking into account the solid indivisible dosage form, is contraindicated in children under 3 years of age.

Impact on the ability to drive vehicles and other mechanisms that require increased concentration

Mezim forte does not affect the speed of psychomotor reactions and the ability to perceive or assess the situation.

Structure

1 tablet contains:

Active substances: pancreatin with minimal enzymatic activity: lipase 3500 U Ph.Eur

amylase 4200 U Ph.Eur

proteases 250 U Ph.Eur.

Excipients: microcrystalline cellulose, sodium carboxymethyl starch (type A), colloidal silicon dioxide, magnesium stearate.

Shell composition: talc, hypromellose, azorubin varnish (E122), simethicone emulsion 30% (dry weight), polyacrylate dispersion 30% (dry weight), titanium dioxide (E171), macrogol 6000.

Method of administration and dosage

The dose is determined individually, depending on the degree of indigestion.

Adults: 1-2 tab.

before meals, without chewing and drinking water.

If necessary, additionally during meals, take another 1-4 tab.

In children: the drug is used as directed by a doctor.

The duration of treatment can vary from a few days (if the digestive process is disturbed due to inaccuracies in the diet) to several months or years

Name ENG

MEZYM FORTE

Clinical and pharmacological group

Enzyme preparation

ATX code

A09AA02 (Multienzymes (lipase, protease etc.))

Dosage

Pancreatin with minimal enzymatic activity: lipases 3500 U Ph.Eur

amylase 4200 U Ph.Eur

proteases 250 U Ph.Eur

Structure

Active ingredients: pancreatin with minimal enzymatic activity: lipase 3500 U Ph.Eur

amylase 4200 U Ph.Eur

proteases 250 U Ph.Eur.

...

Excipients: microcrystalline cellulose, sodium carboxymethyl starch (type A), colloidal silicon dioxide, magnesium stearate.

Shell composition: talc, hypromellose, azorubin varnish (E122), simethicone emulsion 30% (dry weight), polyacrylate dispersion 30% (dry weight), titanium dioxide (E171), macrogol 6000.

Indications

Lack of exocrine pancreatic function (chronic pancreatitis, cystic fibrosis)

chronic inflammatory-dystrophic diseases of the stomach, intestines, liver, gallbladder.

Conditions after resection or irradiation of these organs, accompanied by impaired digestion of poverty, flatulence, diarrhea (as part of combination therapy)

to improve digestion, eat in patients with normal gastrointestinal tract function in case of nutritional errors

preparation for X-ray and ultrasound examination of the abdominal organs.

Contraindications

Hypersensitivity to drug components

acute pancreatitis or chronic pancreatitis in the acute stage.

Nevertheless, the appointment is acceptable in the phase of damping exacerbation with the expansion of the diet, if there are signs of indigestion

hereditary galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome

children's age up to 3 years (for this dosage form).

INN / Active ingredient

Pancreatin

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

Specifications

Category

Preparations for the gastrointestinal tract

,

Enzymes

Scope of the drug

Gastrointestinal tract

Release form

Tablet

Manufacturer country

Germany

Package quantity, pcs

80

Scope of application

Gastroenterology

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Berlin-Chemie

The amount of the dosage form in the primary package

20 pcs.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Digestive Enzyme Remedy

Anatomical and therapeutic characteristics

A09AA02 Polyenzyme preparations (lipase + protease, etc.)

Dosage form

Film-coated tablets

Expiration date in days

1095

Package weight, g

60

Mode of application

:

The dose is determined individually, depending on the degree of indigestion.

Adults: 1-2 tab.

before meals, without chewing and drinking water.

If necessary, additionally during meals, take another 1-4 tab.

In children: the drug is used as directed by a doctor.

The duration of treatment can vary from several days (if the digestion process is disturbed due to dietary errors) to several months or years (if constant replacement therapy is necessary).

Dosage (volume) of the substance in the preparation

:

Pancreatin with minimal enzymatic activity: lipases 3500 U Ph.Eur

amylase 4200 U Ph.Eur

proteases 250 U Ph.Eur

Information on technical characteristics, delivery set, country of manufacture