Magnelis B6 tab. p / o No. 90

pharmachologic effect

Magnelis B6 - replenishes magnesium deficiency.

Magnesium is a vital element that is found in all tissues of the body and is essential for the normal functioning of cells.

Participates in most metabolic reactions, in the regulation of the transmission of nerve impulses and in muscle contraction, has an antispasmodic, antiarrhythmic, antiplatelet effect.

The body receives magnesium from food.

Lack of magnesium in the body can be observed in violation of the diet (diet) or with an increase in the need for magnesium (with increased physical and mental stress, stress, pregnancy, use of diuretics).

Pyridoxine (vitamin B6) is involved in many metabolic processes, in the regulation of the metabolism of the nervous system.

Vitamin B6 improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.

Serum magnesium content

:

from 12 to 17 mg / l (0.5-07 mmol / l) indicates a moderate magnesium deficiency

below 12 mg / L (0.5 mmol / L) indicates severe magnesium deficiency.

Pharmacokinetics

Absorption of magnesium in the gastrointestinal tract is 50% of the oral dose.

It is excreted mainly through the kidneys.

In the kidneys, after glomerular filtration of 70% of the magnesium present in the plasma, it is reabsorbed by the renal tubules in a proportion of 95% - 97%.

Indications

: an established magnesium deficiency isolated or associated with other deficiency conditions.

Contraindications

Hypersensitivity to the drug components, severe renal failure (creatinine clearance less than 30 ml / min), phenylketonuria.

Children's age - up to 6 years.

With caution: with moderate renal failure, as there is a risk of developing hypermagnesemia.

Side effects

From the digestive tract: abdominal pain, constipation, nausea, vomiting, flatulence.

Allergic reactions: possible allergic reactions to the components of the drug.

Interaction

The simultaneous use of drugs containing phosphates or calcium salts can significantly reduce the absorption of magnesium in the gastrointestinal tract.

Magnesium preparations reduce the absorption of tetracycline, it is recommended to separate the intake of these drugs at three-hour intervals.

Magnesium weakens the effect of oral thrombolytic agents, reduces the absorption of iron.

Vitamin B6 inhibits the activity of levodopa.

How to take, course and dosage

Before taking the drug, you should consult your doctor.

Adults are advised to take 6-8 tablets per day.

Children over 6 years old (weighing more than 20 kg) 4-6 tablets per day.

The daily dose should be divided into 2-3 doses, taken with meals with a glass of water.

Treatment should be discontinued after normalization of the concentration of magnesium in the blood.

Overdose

Symptoms: drop in blood pressure, nausea, vomiting, slow reflexes, anuria, respiratory depression, coma, cardiac arrest.

Treatment: rehydration, forced diuresis.

Renal failure requires hemodialysis or peritoneal dialysis.

Release form

: pills

Storage conditions

: at a temperature not exceeding 25 В° C.

Shelf life

: 2 years

Name ENG

Magnelis B6

Clinical and pharmacological group

Magnesium pyridoxine

ATX code

Combination of various magnesium salts

Dosage

470mg + 5mg

Structure

The composition of 1 tablet contains: active substances: magnesium lactate dihydrate - 470 mg (in terms of Mg2 + - 48 mg)

pyridoxine hydrochloride - 5 mg

auxiliary components (core): kaolin - 41 mg

sucrose - 27.4 mg

magnesium stearate - 6.8 mg

talc - 6.8 mg

carmellose sodium - 34 mg

acacia gum - 25 mg

Kollidone SR (polyvinyl acetate - 80% povidone - 19% sodium lauryl sulfate - 0.8% silicon dioxide - 0.2%) - 34 mg

shell: talc - 15 mg

sucrose - 166.7 mg

titanium dioxide - 9 mg

gelatin - 0.9 mg

beeswax - 0.4 mg

acacia gum - 4 mg

kaolin - 54 mg.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

INN / Active ingredient

Pyridoxine, magnesium lactate

Specifications

Category

Vitamin and mineral complexes

Scope of the medicinal product

General

Release form

Tablet

Manufacturer country

Russia

Package quantity, pcs

90

Minimum age from

6 years

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

OTCPharm

The amount of the dosage form in the primary package

90 pcs.

Primary packaging type

Bank

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Magnesium drug

Anatomical and therapeutic characteristics

A12CC01 Magnesium chloride

Dosage form

Film-coated tablets

The target audience

Children

Dosage (volume) of the substance in the preparation

magnesium lactate 470 mg, pyridoxine hydrochloride 5 mg

Expiration date in days

1095

Package weight, g

2

Mode of application

:

Before taking the drug, you should consult your doctor.

Adults are advised to take 6-8 tablets per day.

Children over 6 years old (weighing more than 20 kg) 4-6 tablets per day.

The daily dose should be divided into 2-3 doses, taken with meals with a glass of water.

Treatment should be discontinued after normalization of the concentration of magnesium in the blood.

Information on technical characteristics, delivery set, country of manufacture