Levomycetin, left 5 ml (chloramphenicol)

Latin name

LEVOMYCETIN

Release form

Levomycetin. Eye drops

Packaging

In a polymeric dropper bottle 5 ml of a solution of eye drops.

Pharmacological action

Broad-spectrum antibiotic. The antimicrobial mechanism is associated with a violation of the synthesis of proteins of microorganisms. It has a bacteriostatic effect. Active against gram-positive bacteria: Staphylococcus spp., Streptococcus spp. gram-negative bacteria: Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Haemophilus influenzae, Salmonella spp., Shigella spp., Klebsiella spp., Serratia spp., Yersinia spp., Proteus spp., Rickettsia spp. active against Spirochaetaceae, some large viruses.

Chloramphenicol is active against strains resistant to penicillin, streptomycin, sulfonamides.

The resistance of microorganisms to chloramphenicol develops relatively slowly.

Indications

Bacterial infections of the eye caused by susceptible microflora:

Conjunctivitis.

Keratitis.

blepharitis.

Contraindications

hemopoiesis inhibition

skin diseases (psoriasis, eczema, fungal diseases)

pregnancy

newborn children

individual intolerance to the drug.

Use during pregnancy and lactation

Contraindicated in pregnancy.

Composition

1 ml eye drops 0.25% contain: chloramphenicol - 2.5 mg:

Excipients: boric acid - 20 mg, purified water - up to 1 ml.

Dosage and administration

The drug is instilled in a conjunctival sac, 1 drop 3-4 times / day.

If the patient takes the drug at his discretion, it is not recommended to use more than three days without consulting a doctor.

Side effects

Allergic reactions may develop.

Drug Interaction

Co-administration with sulphonylamide preparations is not recommended to prevent exacerbation of hematopoiesis.

overdose

Symptoms: gray syndrome in preterm and newborn infants at high doses (the cause of development is accumulation of chloramphenicol due to immaturity of liver enzymes, and its direct toxic effect on the myocardium) - bluish-gray skin color, low body temperature, irregular breathing, no reactions, cardiovascular failure. Mortality - up to 40%. Treatment: hemosorption, symptomatic therapy.

Storage conditions

Store in a dark place at a temperature not exceeding 25 ° C.

Expiration

2 years.

Active substance

Chloramphenicol

dosage form

Dosage form

eye drops



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