Knox spray naz. 0.5mg / ml vial 20ml
Category
Runny nose
Scope of the drug
Ear, Throat, Nose
Release form
Spray
Manufacturer country
Ukraine
Package quantity, pcs
one
Release form, composition and packaging
?
Nasal spray in the form of a colorless or slightly yellowish, transparent liquid with a specific odor.
1 ml
oxymetazoline hydrochloride 500 mcg
racemic camphor, menthol, eucalyptol, disubstituted sodium phosphate, sodium edetate (Trilon B), benzalkonium chloride, propylene glycol, purified water.
10 ml - polymer bottles (1) with spray stoppers - cardboard packs.
20 ml - polymer bottles (1) with spray stoppers - cardboard packs.
pharmachologic effect
Noxprey is an? -Adrenomimetic, an imidazoline derivative, belongs to vasoconstrictor agents for local use.
When it enters the nasal cavity, the drug narrows the arterioles of the mucous membrane of the nasal cavity, as a result of which swelling, hyperemia, exudation decreases, nasal breathing is restored, and nasal discharge decreases.
Noxprey also reduces the swelling of the mucous membrane around the opening of the Eustachian tube, improving drainage in Eustachitis and otitis media.
The essential oils that make up the drug help to eliminate irritation of the nasal mucosa, protect it from excessive drying.
Pharmacokinetics
Local vasoconstriction of the nasal mucosa and paranasal sinuses occurs 5-10 minutes after the injection of Noxprey into the nasal cavity and lasts up to 10-12 hours.
Indications for use
- acute rhinitis of allergic or infectious and inflammatory etiology
- sinusitis
- nasal congestion and difficulty in nasal breathing with colds
- eustachitis, otitis media
- to facilitate rhinoscopy and other manipulations in the nasal cavity.
Contraindications for use
- hypersensitivity to drug components - atrophic rhinitis - children under 6 years old - pregnancy - lactation period. The drug is used with caution in chronic heart failure, arrhythmias, severe atherosclerosis, arterial hypertension, thyrotoxicosis, diabetes mellitus, chronic renal failure, angle-closure glaucoma, prostatic hyperplasia with clinical symptoms while taking MAO inhibitors, tricyclic antidepressants. To prevent the spread of infection, one bottle should not be used by several people. Long-term use and drug overdose should be avoided. Long-term use of decongestants can reduce their effectiveness.Abuse of these agents can cause atrophy of the nasal mucosa and reactive hyperemia with rhinitis medicamentosa.
Dosage regimen
The tip of the bottle nozzle is inserted into each nasal passage and sharply pressed once on the bottle.
During injection, air is drawn in through the nose.
Do not tilt your head back and turn the bottle over when injecting Noxspray.
Children aged 6 to 12 years old are used 1 injection into each nasal passage 2 times / day, children over 12 years old and adults - 1-2 injections into each nasal passage 2 times / day.
The duration of use should not exceed 7 days.
Overdose
With a significant overdose or with accidental oral administration, the following symptoms may occur: miosis, nausea, vomiting, cyanosis, hyperthermia, tachycardia, arrhythmia, vascular insufficiency, arterial hypertension, respiratory disorders, pulmonary edema, cardiac arrest, mental disorders.
It is extremely rare - depression of the central nervous system with the possible development of coma.
Treatment: in case of an overdose of the drug, the stomach is washed and symptomatic therapy is performed.
Side effect
Sometimes: burning or dryness of the nasal membranes, sneezing.
In rare cases: reactive hyperemia.
Repeated overdose with local nasal application leads to such systemic sympathomimetic effects as tachycardia, insomnia, anxiety, increased blood pressure, headache, nausea.
It is extremely rare when using Knoxprey.
Name ENG
NOKSPAY
Clinical and pharmacological group
A vasoconstrictor drug for local use in ENT practice
ATX code
Oxymetazoline
Dosage
0.05% x 20ml
Structure
Active ingredients: oxymetazoline hydrochloride 0.5 mg
Excipients: racemic camphor
menthol
eucalyptol
sodium phosphate disubstituted
sodium edetate (Trilon B)
benzalkonium chloride
propylene glycol
purified water oxymetazoline hydrochloride 500 mcg.
Indications
acute rhinitis of allergic or infectious-inflammatory etiology
sinusitis
nasal congestion and difficulty in nasal breathing with colds
eustachitis, otitis media
to facilitate rhinoscopy and other manipulations in the nasal cavity.
Contraindications
hypersensitivity to drug components
atrophic rhinitis
children under 6 years old
pregnancy
lactation period.
The drug is used with caution in chronic heart failure, arrhythmias, severe atherosclerosis, arterial hypertension, thyrotoxicosis, diabetes mellitus, chronic renal failure, angle-closure glaucoma, prostatic hyperplasia with clinical symptoms
while taking MAO inhibitors, tricyclic antidepressants.
To prevent the spread of infection, one bottle should not be used by several people.
Long-term use and drug overdose should be avoided.
Long-term use of decongestants can reduce their effectiveness.
Abuse of these agents can cause atrophy of the nasal mucosa and reactive hyperemia with rhinitis medicamentosa.
Storage conditions and periods
At a temperature not higher than 25 degrees.
Expiration date: 3 years
INN / Active ingredient
oxymetazoline hydrochloride
Specifications
Category
Runny nose
Scope of the drug
Ear, Throat, Nose
Release form
Spray
Manufacturer country
Ukraine
Package quantity, pcs
one
Scope of application
Virology
Minimum age from
6 years
Way of introduction
Through the respiratory tract
Vacation conditions
Without recipe
Volume, ml.
20 ml
Brand name
Sperko Ukraine SP
The amount of the dosage form in the primary package
20 ml
Primary packaging type
Bottle with spray stopper
Type of consumer packaging
Pack of cardboard
Pharmaco-therapeutic group
Decongestant - alpha adrenergic agonist
Anatomical and therapeutic characteristics
R01AA05 Oxymetazoline
Dosage form
Nasal spray
Dosage (volume) of the substance in the preparation
500 mcg
Expiration date in days
1095
The target audience
Children
Package weight, g
twenty
Mode of application
:
The tip of the bottle nozzle is inserted into each nasal passage and sharply pressed once on the bottle.
During injection, air is drawn in through the nose.
Do not tilt your head back and turn the bottle over when injecting Noxspray.
Information on technical characteristics, delivery set, country of manufacture