Indinol Forto capsules, 60 pcs. (Yndolkarbynol)
Special Price
$70.29
Regular Price
$71.00
In stock
SKU
florida468104
Release form
Capsules. Buy Indinol Forto capsules, 60 pcs. (Yndolkarbynol) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Capsules. Buy Indinol Forto capsules, 60 pcs. (Yndolkarbynol) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Release form
Capsules.
Packing
60 pcs.
Pharmacological action
Selective modulator of estrogen receptors.
Indinol Forto is a universal corrector of pathological hyperplastic processes in breast tissue. The therapeutic effect of Indinol Forto is based on its antiestrogenic and antiproliferative effect.
The main property of Indinol Forto is its ability to cause selective death of breast cells with abnormally high proliferative activity.
Indolcarbinol, which is part of the Indinol Forto preparation, modulates the cytochrome system so that the resulting cytochrome P450 isoform - CYP1A1 hydroxylates estrogens in the 2nd position, with the formation of 2-hydroxyestrone (2-OHE1).
The resulting metabolite is an antagonist of the estrogen receptor and blocks its activation by estrogens themselves, as well as their dangerous metabolites, in particular, 16 - - hydroxyestrone (16 - HEE1), the proportion of which among the metabolites is reduced.
Thus, the induction of estrogen-dependent genes is suppressed, and the cell ceases to receive excessive estrogen-dependent stimulation. The drug also blocks other signaling mechanisms (cytokine), stimulating abnormal cell growth in the tissues of the mammary gland, by suppressing signaling cascades from the corresponding receptors.
The course use of the drug helps to reduce the intensity and the disappearance of pain in the mammary gland with cyclic mastalgia (mastodynia).
The use of Indinol Forto does not increase body weight. Indinol Forto is a non-toxic drug (LD50> 5 g / kg).
Indications
Cyclic mastalgia, including on the background of benign breast hyperplasia.
Contraindications
The drug should not be used in the presence of any of the following conditions:
hypersensitivity to the components of the drug
hereditary galactose intolerance, lactase deficiency or glucose-galactose malabsorption
pregnancy and breastfeeding
children under 18 years of age.
Use during pregnancy and lactation
Indinol® Forto is contraindicated during pregnancy and breastfeeding.
Special instructions
Available as a prescription.
Influence on the ability to drive vehicles and other mechanisms that require an increased concentration of attention
Based on the pharmacodynamics and profile of undesirable effects, IndinolВ® Forto is unlikely to affect the ability to drive vehicles and work with machinery.
Dosage and administration
Inside, 2 times a day, 200 mg each. The daily dose of the drug is 400 mg.
Capsules are taken before meals.
Duration of treatment 6 months.
Side effects of
From the reproductive system: menstrual irregularities in the form of lengthening or shortening.
From the digestive system: epigastric pain.
Laboratory indicators: an increase in the concentration of thyroid-stimulating and follicle-stimulating hormones, prolactin and estradiol, a decrease in the concentration of creatinine, eosinophilia.
Other: weight loss. If any of the side effects indicated in the instructions are aggravated, or if you notice any other side effects not listed in the instructions, inform your doctor.
Drug interaction
Indole carbinol affects the activity of P450 cytochrome isoenzymes, therefore caution should be exercised when used together with drugs in the metabolism of which P450 cytochrome isoenzymes are involved (indirect anticoagulants, glucocorticosteroids, oral antipyretic drugs, antipyretic drugs, hormones), since dose adjustment may be required.
overdose
Symptoms: Possible symptoms of overdose include nausea, vomiting, diarrhea.
Treatment: The specific antidote is unknown.
Symptomatic treatment is recommended if Indinol® Forto overdose is suspected.
Storage conditions
Store in a dry, dark place at a temperature not exceeding 25 ° C.
Keep out of the reach and sight of children.
Shelf life
2 years.
Pharmacy conditions
without prescription
Dosage form
capsules
Prescribing
Prescribing
Adults as prescribed by a doctor
MiraksBioFarma, Russia
Indinol Forto capsules, 60 pcs. (Yndolkarbynol) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Indinol Forto capsules, 60 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.
Capsules.
Packing
60 pcs.
Pharmacological action
Selective modulator of estrogen receptors.
Indinol Forto is a universal corrector of pathological hyperplastic processes in breast tissue. The therapeutic effect of Indinol Forto is based on its antiestrogenic and antiproliferative effect.
The main property of Indinol Forto is its ability to cause selective death of breast cells with abnormally high proliferative activity.
Indolcarbinol, which is part of the Indinol Forto preparation, modulates the cytochrome system so that the resulting cytochrome P450 isoform - CYP1A1 hydroxylates estrogens in the 2nd position, with the formation of 2-hydroxyestrone (2-OHE1).
The resulting metabolite is an antagonist of the estrogen receptor and blocks its activation by estrogens themselves, as well as their dangerous metabolites, in particular, 16 - - hydroxyestrone (16 - HEE1), the proportion of which among the metabolites is reduced.
Thus, the induction of estrogen-dependent genes is suppressed, and the cell ceases to receive excessive estrogen-dependent stimulation. The drug also blocks other signaling mechanisms (cytokine), stimulating abnormal cell growth in the tissues of the mammary gland, by suppressing signaling cascades from the corresponding receptors.
The course use of the drug helps to reduce the intensity and the disappearance of pain in the mammary gland with cyclic mastalgia (mastodynia).
The use of Indinol Forto does not increase body weight. Indinol Forto is a non-toxic drug (LD50> 5 g / kg).
Indications
Cyclic mastalgia, including on the background of benign breast hyperplasia.
Contraindications
The drug should not be used in the presence of any of the following conditions:
hypersensitivity to the components of the drug
hereditary galactose intolerance, lactase deficiency or glucose-galactose malabsorption
pregnancy and breastfeeding
children under 18 years of age.
Use during pregnancy and lactation
Indinol® Forto is contraindicated during pregnancy and breastfeeding.
Special instructions
Available as a prescription.
Influence on the ability to drive vehicles and other mechanisms that require an increased concentration of attention
Based on the pharmacodynamics and profile of undesirable effects, IndinolВ® Forto is unlikely to affect the ability to drive vehicles and work with machinery.
Dosage and administration
Inside, 2 times a day, 200 mg each. The daily dose of the drug is 400 mg.
Capsules are taken before meals.
Duration of treatment 6 months.
Side effects of
From the reproductive system: menstrual irregularities in the form of lengthening or shortening.
From the digestive system: epigastric pain.
Laboratory indicators: an increase in the concentration of thyroid-stimulating and follicle-stimulating hormones, prolactin and estradiol, a decrease in the concentration of creatinine, eosinophilia.
Other: weight loss. If any of the side effects indicated in the instructions are aggravated, or if you notice any other side effects not listed in the instructions, inform your doctor.
Drug interaction
Indole carbinol affects the activity of P450 cytochrome isoenzymes, therefore caution should be exercised when used together with drugs in the metabolism of which P450 cytochrome isoenzymes are involved (indirect anticoagulants, glucocorticosteroids, oral antipyretic drugs, antipyretic drugs, hormones), since dose adjustment may be required.
overdose
Symptoms: Possible symptoms of overdose include nausea, vomiting, diarrhea.
Treatment: The specific antidote is unknown.
Symptomatic treatment is recommended if Indinol® Forto overdose is suspected.
Storage conditions
Store in a dry, dark place at a temperature not exceeding 25 ° C.
Keep out of the reach and sight of children.
Shelf life
2 years.
Pharmacy conditions
without prescription
Dosage form
capsules
Prescribing
Prescribing
Adults as prescribed by a doctor
MiraksBioFarma, Russia
Indinol Forto capsules, 60 pcs. (Yndolkarbynol) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Indinol Forto capsules, 60 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.
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