Hexoral tabs tab d / rassas

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SKU
FL102038301
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Category

Sore throat

Scope of the drug

Ear, Throat, Nose

Release form

Tablet

Manufacturer country

Germany

Package quantity, pcs

twenty

Description

Release form, composition and packaging

Lozenges are round, biconvex, opaque, with a rough surface from white or yellowish white to light gray or yellowish gray

uneven coloring, the presence of air bubbles and slight unevenness of the edges are allowed

the appearance of a white bloom (dusting) is possible.

1 tab.

chlorhexidine dihydrochloride 5 mg

benzocaine

1.5 mg

isomalt, peppermint oil, menthol, thymol, aspartame, purified water.

10 pieces.

- blisters (2) - cardboard packs.

pharmachologic effect

Combined preparation for topical use.

The double action of the drug is due to the presence of 2 active substances.

The antibacterial activity of the drug is due to the presence of chlorhexidine.

The local anesthetic benzocaine works to reduce pain symptoms.

Chlorhexidine has a broad spectrum of antibacterial action against gram-positive and gram-negative bacteria

acts by destroying the cytoplasmic membrane of a bacterial cell.

Ineffective against yeast fungi, dermatophytes, mycobacteria, some species of Pseudomonas and Proteus.

Chlorhexidine is most effective in a neutral or slightly alkaline environment.

In an acidic environment, its activity decreases.

Efficacy is reduced in the presence of soaps, blood and purulent discharge.

The use of chlorhexidine lozenges leads to a significant reduction in the bacterial content of saliva.

The use of chlorhexidine for several months is accompanied by a decrease in its effectiveness by reducing the sensitivity of bacteria.

Benzocaine is a local anesthetic that relieves pain in the mouth and throat quickly and lastingly.

Benzocaine penetrates the lipophilic areas of the cell membrane and acts on the peripheral pain receptors of the mucous membrane and skin.

The anesthetic effect of benzocaine occurs in 15-30 seconds

as the substance is diluted with saliva, the anesthetic effect gradually decreases (within 5-10 minutes).

Pharmacokinetics

Chlorhexidine

There is no clinical data on the absorption of chlorhexidine through the oral mucosa of humans.

Chlorhexidine can persist in saliva for up to 8 hours.

Benzocaine

Benzocaine is poorly soluble in water, which causes its slow absorption.

Like all ether derivatives of PABA, it is cleaved by esterase in blood plasma and liver.

As a result, PABA and ethanol are formed, which is metabolized to acetyl coenzyme A. PABA is conjugated with glycine or excreted unchanged by the kidneys.

Indications for use

Infectious and inflammatory diseases of the pharynx or oral cavity:

- pharyngitis, tonsillitis and other inflammatory diseases of the pharynx

- stomatitis

- gingivitis.

Contraindications for use

- wound and ulcerative lesions of the oral cavity or pharynx

- low concentration of cholinesterase in blood plasma

- phenylketonuria

- children under 4 years old

- hypersensitivity to drug components.

With caution and only under the supervision of a physician, the drug should be used for erosive, desquamative changes in the oral mucosa.

Dosage regimen

Apply topically.

The tablet should be slowly dissolved in the mouth until it is completely dissolved.

The drug should be started immediately after the first symptoms of the disease appear and continued for several days after the symptoms disappear.

Adults and children over 12 years old are prescribed 1 tab.

every 1-2 hours as needed, but not more than 8 tablets / day.

Children aged 4-12 years are prescribed up to 4 tablets / day.

Use in children is possible only as directed by a doctor.

Do not use the drug in children under 4 years of age.

Overdose

When used correctly, an overdose of the drug is impossible, because

chlorhexidine is practically not absorbed into the bloodstream, and the amount of absorbed benzocaine is extremely small.

Chlorhexidine

Chlorhexi

Name ENG

HEXORAL TABS

Clinical and pharmacological group

Drug with antimicrobial and local anesthetic action for local use in ENT practice and dentistry

ATX code

Other drugs

Dosage

1.5mg + 5mg

Structure

1 tablet contains: active ingredients: chlorhexidine dihydrochloride - 5 mg, benzocaine - 1.5 mg.

Excipients: isomalt, peppermint oil, menthol, thymol, aspartame, purified water.

Indications

inflammatory and infectious diseases of the mouth and pharynx

severe, accompanied by fever or purulent diseases of the oral cavity and pharynx, requiring the appointment of antibiotics and sulfonamides, tonsillitis (as part of complex therapy)

tonsillitis (including tonsillitis with lesions of the lateral ridges, Plout-Vincent tonsillitis)

pharyngitis

gingivitis and bleeding gums

periodontal disease (periodontal diseases and their symptoms)

stomatitis (inflammation of the oral mucosa), glossitis (inflammation of the tongue), aphthous ulcers (painful inflammation with superficial tissue defects) in order to prevent superinfections

infection of the alveoli (tooth holes) after tooth extraction

fungal infections of the mouth and pharynx, especially candidal stomatitis (thrush)

before and after operations in the oral cavity and pharynx

additional oral hygiene for common diseases

elimination of bad breath, especially in the case of collapsing tumors of the oral cavity and pharynx

adjuvant in the treatment of colds.

INN / Active ingredient

benzocaine, chlorhexidine dihydrochloride

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

Contraindications

Hypersensitivity to any component of the drug

children's age (up to 3 years).

Specifications

Category

Sore throat

Scope of the drug

Ear, Throat, Nose

Release form

Tablet

Manufacturer country

Germany

Package quantity, pcs

twenty

Minimum age from

4 years old

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Hexoral

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antiseptic

Anatomical and therapeutic characteristics

R02AA20 Other antiseptics

Dosage form

Lozenges

Expiration date in days

1095

The target audience

Children

Dosage (volume) of the substance in the preparation

chlorhexidine dihydrochloride - 5 mg, benzocaine - 1.5 mg.

Package weight, g

one

Mode of application

:

Apply topically.

The tablet should be slowly dissolved in the mouth until it is completely dissolved. : as a rule, appoint 1 tab.

every 1-2 hours as needed, but not more than 8 tablets / day. < br> < br> Children aged 4-12 years: appoint up to 4 tablets / day. < br> < br> Use in children is possible only as directed by a doctor. < br> < br> Do not use the drug in children under 4 years of age.

Information on technical characteristics, delivery set, country of manufacture

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