Details

Description

Release form

Powder for preparation of oral solution.

Packaging

10 pieces.

pharmachologic effect

Pharmaceutical group: Hypoammonaemic drug.

Pharmaceutical action: Glutargin alkocline is a compound of arginine and glutamic acid, which play an important role in providing biochemical processes of neutralization and excretion of a highly toxic metabolite of nitrogenous substances - ammonia.

It has a hepatoprotective effect, possessing antioxidant, antihypoxic and membrane stabilizing activity, and has a positive effect on the processes of energy supply in hepatocytes.

In case of alcohol intoxication, Glutargin alkocline stimulates the utilization of alcohol in the monooxygenase system of the liver, prevents the inhibition of the key enzyme for utilizing ethanol - alcohol dehydrogenase

accelerates the inactivation and elimination of toxic products of ethanol metabolism as a result of an increase in the formation and oxidation of succinic acid

reduces the depressing effect of alcohol on the central nervous system due to the neurotransmitter properties of excitatory glutamic acid.

Glutargin alkocline does not have embryotoxic, gonadotoxic and mutagenic effects, does not cause allergic and immunotoxic reactions.

Indications

- prevention of intoxication and hepatotoxic effects of alcohol

- treatment of acute alcoholic intoxication of mild and moderate severity, as well as in the complex therapy of post-intoxication disorders after acute alcohol poisoning of a severe degree.

Contraindications

- hypersensitivity to drug components

- children under 18 years old

- the period of pregnancy and lactation

- phenylketonuria, as the drug contains aspartame

Carefully

- febrile condition

- increased excitability

- severe violations of the filtration (nitrogen excretion) function of the kidneys (creatinine clearance 30 ml / min)

special instructions

When prescribing to patients with dysfunction of the endocrine glands, it should be borne in mind that the drug may slightly increase the secretion of insulin and growth hormones, which does not require correction of drug therapy in patients with diabetes mellitus and / or acromegaly

The effect of the drug on the ability to drive vehicles

The drug does not affect the ability to drive vehicles

Structure

Active ingredient: arginine glutamate (in terms of 100% substance) 1.0 g.

Excipient: glycine 0.50 g, mannitol (E421) 0.79 g, citric acid (without aqueous) 0.60 g, aspartame (E951) 0.06 g, lemon flavoring 0.05 g.

Method of administration and dosage

The drug is prescribed for adults inside, regardless of food intake, we will pre-dissolve the package in?

-?

glasses of water.

For the prevention of intoxication and the hepatotoxic effect of alcohol, 2 packets (2 g of arginine glutamate) are prescribed 1-2 hours before alcohol intake or 1 packet (1 g of arginine glutamate) 1 hour before alcohol intake and 1 packet (1 g of arginine glutamate) for 0, 5 hours after drinking alcohol.

For the treatment of acute alcohol intoxication of mild and moderate severity, 1 packet is prescribed 4 times a day with an interval of 1-2.5 hours, in the next 2-3 days - 1 packet 2 times a day.

In case of severe alcohol poisoning, after a course of intravenous administration of the drug Glutargin Alkoklin, 1 packet is prescribed 2 times a day for 20 days as part of complex therapy.

Side effects

Feelings of mild discomfort in the epigastric region and nausea immediately after using the drug, which go away on their own, can rarely be observed.

Overdose

Symptoms: nausea, vomiting, chest pain, epigastric discomfort, insomnia, transient short-term lowering of blood pressure, atrioventricular block, allergic reactions.

Treatment: symptomatic, if necessary, taking antihistamines, in severe cases - intravenous glucocorticosteroids.

Storage conditions

Store in original packaging, at a temperature not exceeding 25 C. Keep out of the reach of children.

Shelf life

2 years.

Active substance

Arginine glutamate

Name ENG

GLUTARGIN ALKOKLIN

Clinical and pharmacological group

Hypoammonaemic drug

ATX code

Arginine glutamate

Dosage

1g x 3g

Structure

Active ingredient: arginine glutamate (in terms of 100% substance) 1.0 g Excipient: glycine 0.50 g, mannitol (E421) 0.79 G, citric acid (without aqueous) 0.60 g, aspartame (E951 ) 0.06 g, Lemon flavor 0.05 g.

Indications

prevention of intoxication and hepatotoxic effects of alcohol

treatment of acute alcoholic intoxication of mild and moderate severity, as well as in the complex therapy of post-intoxication disorders after acute alcohol poisoning of severe degree

Contraindications

hypersensitivity to drug components

- children under 18 years old

- the period of pregnancy and lactation

- phenylketonuria, as the drug contains aspartame

Carefully

- febrile condition

- increased excitability

- severe violations of the filtration (nitrogen excretion) function of the kidneys (creatinine clearance 30 ml / min).

Storage conditions and periods

At a temperature not exceeding 25 degrees, in the original packaging.

Expiration date: 2 years

INN / Active ingredient

arginine glutamate

Specifications