Genferon Light suppositories vagin./rekt. 125 thousand IU + 5 mg 10 pcs (interferon alfa-2b, Taurine)

Release form

Suppositories vaginal and rectal.

Packing

10 pcs.

Pharmacological action

Genferon Light - a combined drug whose action is due to its constituent components. It has a local and systemic effect.

Interferon alfa-2 has an antiviral, antibacterial and immunomodulating effect.

Under the influence of interferon alpha-2, the activity of natural killers, T-helpers, phagocytes, as well as the intensity of differentiation of B-lymphocytes, is increased in the body.

Activation of leukocytes contained in all layers of the mucous membrane ensures their active participation in the elimination of primary pathological foci and ensures the restoration of secretory immunoglobulin production A.

Interferon alfa-2 also directly inhibits the replication and transcription of viruses, chlamydia.

Taurine, which is part of the drug, has regenerative, reparative, membrane and hepatoprotective, antioxidant, anti-inflammatory properties.

Anestezin is a local anesthetic. It reduces the permeability of the cell membrane for sodium ions, displaces calcium ions from receptors located on the inner surface of the membrane, and blocks the conduction of nerve impulses.

Prevents the occurrence of pain impulses in the endings of sensory nerves and their passage through nerve fibers.

Contraindications

Individual intolerance to interferon and other substances that make up the drug. With caution: exacerbation of allergic and autoimmune diseases.

Use during pregnancy and lactation

Clinical studies have proven the efficacy and safety of Genferon Light in the second and third trimesters of pregnancy.

The safety of the drug in the first trimester of pregnancy has not been studied.

Special instructions

Suppositories for vaginal or rectal use:

Genferon Light does not affect the execution of potentially hazardous activities that require special attention and quick reactions (driving vehicles, machinery, etc.).

Composition

1 suppository contains:

interferon human recombinant alpha-2a - 250,000 IU, 500,000 IU or 1,000,000 IU, as well as taurine 0.01 g and anestezin 0,055 g

excipients:

"solid fat",

600,



polyethylene oxide 1500,

tween 80,

emulsifier T 2,

sodium citrate,

citric acid,

purified water - a sufficient amount to obtain a suppository weighing 1.65 g

Dosage and administration

The drug can be used both vaginally and rectally. The route of administration, dosage and duration of the course depend on age, specific clinical situation and are determined by the attending physician.

In adults and children over 7 years of age, Genferon Light is used at a dosage of 250,000 IU of interferon alfa-2b per suppository. In children under 7 years of age, it is safe to use the drug at a dosage of 125,000 ME interferon alpha-2b per suppository.

Recommended doses and treatment regimens:

Acute infectious and inflammatory diseases of the urogenital tract in children: 1 suppository rectally 2 times a day with a 12-hour interval for 10 days.

Infectious and inflammatory diseases of the urogenital tract in pregnant women: 1 suppository vaginally 2 times a day with a 12-hour interval for 10 days.

Infectious and inflammatory diseases of the urogenital tract in women: 1 suppository (250,000 ME) vaginally or rectally (depending on the nature of the disease) 2 times a day with a 12-hour interval for 10 days. With protracted forms 3 times a week every other day, 1 suppository for 1-3 months.

Acute infectious and inflammatory diseases of viral etiology in children: 1 suppository rectally 2 times a day with a 12-hour interval in parallel with standard therapy for 5 days. If symptoms persist, the course of treatment is repeated after a 5-day interval.

Chronic infectious and inflammatory diseases of viral etiology in children: 1 suppository rectally 2 times a day with a 12-hour interval in parallel with standard therapy for 10 days. Then within 1-3 months - 1 suppository rectally at night every other day.

Side effects

The drug is well tolerated by patients. Local allergic reactions are possible (sensation of itching and burning in the vagina). These phenomena are reversible and disappear within 72 hours after cessation of administration. Continuation of treatment is possible after consultation with a doctor.

To date, no serious or life-threatening side effects have been observed.

Phenomena may occur that occur with all types of interferon alfa-2b, such as chills, fever, fatigue, loss of appetite, muscle and headaches, joint pain, sweating, and leukemia and thrombocytopenia, but more often they occur when the daily dose is exceeded over 10,000,000 ME. In these cases, it is recommended that the attending physician consults to decide on the need to discontinue the drug or reduce the dose.

As with any other interferon alfa drug, if the temperature rises after administration, it is possible to take paracetamol once at a dose of 500-1000 mg for adults and 250 mg for children.

Storage conditions

At 2-8 ° C, keep out of reach of children.

Expiration

2 years.

Active ingredient

Interferon alfa-2b, Taurine



pharmacy terms of prescription

Dosage form

suppositories vaginal

Indications

Hrypp, infection mochev vodyaschyh tract, acute respiratory viral infections, Vahynaln e infection



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