Fluditec syrup 5%, 125 ml (karbotsisteina)

Latin name

Fluditec

Release form

Fluditec. Syrup.

Packaging

in 125 ml glass bottles in a carton pack 1 bottle.

Pharmacological action

Mucolytic drug. Mucolytic and expectorant effect is due to the activation of sialic transferase - an enzyme of goblet cells of the bronchial mucosa. It normalizes the quantitative ratio of acidic and neutral sialomucins of bronchial secretion, restores the viscosity and elasticity of mucus, and facilitates its passage. It promotes the regeneration of the mucous membrane, normalizes its structure, activates the activity of the ciliary epithelium, improves mucociliary clearance. Restores the secretion of immunologically active IgA (specific protection) and the number of sulfhydryl groups of mucus components (non-specific protection).

Pharmacokinetics

Absorption

After oral administration of Cmax in blood serum and in the mucous membrane of the respiratory tract is achieved 2-3 hours after oral administration and remains in the mucous membrane for 8 hours.

Excretion of

It is excreted mainly with urine, partially unchanged , partially - in the form of metabolites.

Indications

acute and chronic bronchopulmonary diseases, (tracheitis, bronchitis, tracheobronchitis, bronchial asthma, bronchiectatic disease) and inflammatory diseases of the nasal cavity, nasopharynx, paranasal sinuses and middle ear (rhinitis, adenoiditis, sinusitis, otitis media) accompanied by the formation of a viscous, difficult to secret (sputum, mucus)

preparation for bronchoscopy and / or bronchography.

Contraindications

hypersensitivity to carbocysteine ​​or other components of the drug

peptic ulcer of the stomach and duodenum (in the acute stage)

chronic glomerulonephritis (in the acute stage), cystitis

three years of age up to three years old.

Precautions: chronic glomerulonephritis (history) gastric and duodenal ulcer (history) pregnancy (II – III trimester - for syrup 50 mg / ml), lactation period (for syrup 50 mg / ml).

Use during pregnancy and lactation

Contraindicated in the first trimester of pregnancy.

Composition

100 ml contain

carbocysteine ​​5 g hydrochloride 5 g srdlp 15 g sucrose - 35 g dye “Sunny sunset” yellow (E110) - 0.0016 g dye patented blue V (E131) - 0.001 g sodium hydroxide - up to pH 6.2 caramel flavor - 0.2 g purified water - up to 100 ml

Dosage and Administration

Inside. Adults 15 ml 3 times a day, preferably 1 hour before meals or 2 hours after eating.

Treatment should not last more than 8-10 days without consulting a doctor (for both dosage forms).

15 ml syrup contains 750 mg carbocysteine.

Side effects of the

Digestive system: nausea, vomiting, diarrhea, epigastric pain, flatulence, gastrointestinal bleeding.

From the side of the central nervous system: dizziness, weakness, malaise.

Allergic reactions: in isolated cases - itching, urticaria, exanthema, angioedema.

Drug Interaction

When used at the same time, Fluditek increases the effectiveness of glucocorticosteroid (mutually) and antibacterial therapy for inflammatory diseases of the upper and lower respiratory tract.

When used at the same time, Fluditek enhances the bronchodilator effect of theophylline.

The activity of carbocysteine ​​is weakened by antitussive and atropine-like agents.

Overdose

Symptoms: gastralgia, nausea, diarrhea.

Treatment: symptomatic therapy.

Storage conditions

The drug should be stored out of the reach of children at a temperature not exceeding 25 ° C.

Expiration

2 years.

Terms

pharmacy leave without a prescription

Dosage form

Dosage form

oral solution

Innotek Internasionaly, France



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