ewss # Allo N50 film- coated tablets
Category
Choleretic
Scope of the drug
Gastrointestinal tract
Manufacturer country
Russia
Brand name
Renewal
Package weight, g
thirty
Dosage form
Round biconvex film-coated tablets from light yellow to yellow.
On a cross section, the core is grayish-black, light inclusions are allowed.
Structure
Composition for one tablet
Active ingredients:
Bile (Bovine bile, dry) 80,000 mg
Garlic onion - 40,000 mg
Activated Carbon (Activated Carbon) - 25,000 mg
Stinging nettle leaves - 5,000 mg
Excipients:
potato starch - 34,250 mg
magnesium oxide - 10,250 mg
colloidal silicon dioxide (aerosil) - 8,250 mg
talc - 5,250 mg
calcium stearate - 2,000 mg
Shell composition:
VIVACOAT PM-2P-169 - 21,000 mg
[hypromellose (hydroxypropyl methylcellulose) - 10,500 mg
titanium dioxide - 5,540 mg
talc - 2,100 mg
macrogol 3350 (polyethylene glycol 3350) - 1,050 mg
hyprolose (hydroxypropyl cellulose) - 1,050 mg
dye quinoline yellow - 0.430 mg
iron dye yellow oxide - 0.305 mg
dye sunset yellow] - 0.025 mg
polyvinyl alcohol - 1.045 mg
talc - 0.600 mg
macrogol 3350 (polyethylene glycol 3350) - 0.295 mg
polysorbate 80 (tween 80) - 0.060 mg
Special conditions
Influence on the ability to drive vehicles and mechanisms
The use of the drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.
Drug interactions
Preparations containing aluminum hydroxide, cholestyramine, colestipol reduce absorption and reduce the effect of the drug.
Simultaneous reception is impractical.
Pharmacodynamics
Choleretic (cholekinetic and choleretic) agent, reduces the processes of putrefaction and fermentation in the intestines.
Strengthens the secretory function of liver cells, reflexively increases the secretory and motor activity of the organs of the gastrointestinal tract.
Strengthens the formation of bile and bile acids.
The action of bile is due to the reflex effect on the secretory function of the liver parenchyma.
Bile also enhances the secretory and motor functions of the gastrointestinal tract.
The substances contained in garlic enhance the secretory and motor function of the gastrointestinal tract, stimulate the secretion of bile.
Nettle leaves have choleretic and anti-inflammatory properties.
Activated carbon is an adsorbent that binds toxic substances in the gastrointestinal tract.
Pharmokinetics
The drug is well absorbed in the gastrointestinal tract.
Cholic and chenodeoxycholic acids contained in the preparation undergo 7-alpha dehydroxylation in the intestine.
Chenodeoxycholic acid, in addition, undergoes metabolism in the liver: it conjugates with amino acids, is secreted into bile, from where it is again secreted into the intestine, then partially reabsorbed
the rest is excreted through the intestines.
Indications
As part of complex therapy: chronic reactive hepatitis, cholangitis, acalculous (non-calculous) cholecystitis, hypokinetic biliary dyskinesia, atonic constipation, postcholecystectomy syndrome.
Contraindications
Hypersensitivity to the drug components, calculous cholecystitis, obstructive jaundice, acute hepatitis, acute and subacute liver dystrophy, gastric ulcer and duodenal ulcer (in the acute phase), acute enterocolitis, acute pancreatitis, children under 12 years of age.
Application during pregnancy and during breastfeeding
The use of the drug during pregnancy and during breastfeeding is possible if the expected benefit to the mother outweighs the potential risk to the fetus and child.
A doctor's consultation is required.
Overdose
Possible diarrhea, nausea, heartburn, pruritus, increased activity of liver" transaminases in the blood serum.
Treatment: symptomatic.
Side effects
Structure
Structure
Composition for one tablet
Active ingredients:
Bile (Bovine bile, dry) 80,000 mg
Garlic onion - 40,000 mg
Activated Carbon (Activated Carbon) - 25,000 mg
Stinging nettle leaves - 5,000 mg
Excipients:
potato starch - 34,250 mg
magnesium oxide - 10,250 mg
colloidal silicon dioxide (aerosil) - 8,250 mg
talc - 5,250 mg
calcium stearate - 2,000 mg
Shell composition:
VIVACOAT PM-2P-169 - 21,000 mg
[hypromellose (hydroxypropyl methylcellulose) - 10,500 mg
titanium dioxide - 5,540 mg
talc - 2,100 mg
macrogol 3350 (polyethylene glycol 3350) - 1,050 mg
hyprolose (hydroxypropyl cellulose) - 1,050 mg
dye quinoline yellow - 0.430 mg
iron dye yellow oxide - 0.305 mg
dye sunset yellow] - 0.025 mg
polyvinyl alcohol - 1.045 mg
talc - 0.600 mg
macrogol 3350 (polyethylene glycol 3350) - 0.295 mg
polysorbate 80 (tween 80) - 0.060 mg
Specifications
Category
Choleretic
Scope of the drug
Gastrointestinal tract
Manufacturer country
Russia
Brand name
Renewal
Package weight, g
thirty
"