Enterosgel paste for oral administration, tube, 225 g, # 1

Pharmacological action - detoxifying, absorbing.

Pharmacodynamics

Enterosgel is a gel-like enterosorbent.

It is a spatially crosslinked organosilicon matrix that forms pores filled with water.

The specified pore sizes provide sorption selectivity.

Enterosgel absorbs and removes from the body mainly medium-molecular toxic substances.

Enterosgel has hydrophobic properties.

Enterosgel does not stick to mucous membranes, does not injure them and does not penetrate into the tissues of the body.

Enterosgel has pronounced sorption and detoxification properties.

In the lumen of the gastrointestinal tract, the drug binds and removes from the body endogenous and exogenous toxic substances of various nature, including bacteria and bacterial toxins, antigens, food allergens, drugs and poisons, heavy metal salts, alcohol.

The drug also sorbs some metabolic products of the body, including an excess of bilirubin, urea, cholesterol and lipid complexes, as well as metabolites responsible for the development of endogenous toxicosis.

Enterosgel does not reduce the absorption of vitamins and microelements, contributes to the restoration of disturbed intestinal microflora and does not affect its motor function.

Pharmacokinetics

Not absorbed in the digestive tract.

It is allocated unchanged within 12 hours.

Indications

In adults and children, as a detoxifying agent:

acute and chronic intoxication of various origins

acute poisoning with potent and poisonous substances (including drugs, alcohol, alkaloids, heavy metal salts)

acute intestinal infections of any genesis as part of complex therapy (including toxic infections, salmonellosis, dysentery, diarrheal syndrome of non-infectious origin, dysbiosis)

purulent-septic diseases, accompanied by severe intoxication, as part of complex therapy

food and drug allergies

hyperbilirubinemia (viral hepatitis)

hyperazotemia (chronic renal failure)

prevention of chronic intoxication among workers in hazardous industries (professional intoxication with polytropic chemical agents, xenobiotics, incorporated radionuclides, compounds of lead, mercury, arsenic, petroleum products, organic solvents, nitrogen oxides, carbon, fluorides, heavy metal salts).

Contraindications

individual intolerance to the drug

intestinal atony.

Application during pregnancy and lactation

Enterosgel is not contraindicated during pregnancy and lactation (breastfeeding).

special instructions

Enterosgel can be used in combination therapy with other drugs, subject to the rule of separate administration in time - 1-2 hours before or after taking other drugs.

The results of published clinical studies of recent years (see Clinical guidelines Obstetrics and Gynecology", 4th edition, revised and updated, M. "GEOTAR-Media", 2014), allows us to recommend the drug Enterosgel as part of the complex therapy of patients with endometritis and gestational pyelonephritis ...

Enterosgel (polymethylsiloxane polyhydrate) has pronounced sorption and detoxification properties.

In the lumen of the gastrointestinal tract, polymethylsiloxane polyhydrate binds and removes from the body endogenous and exogenous toxic substances of various natures, including bacteria and bacterial toxins, antigens, food allergens, drug metabolites, and heavy metal salts.

The drug also absorbs metabolic products of the body, incl.

excess of bilirubin, urea, cholesterol and lipid complexes, as well as metabolites responsible for the development of endogenous toxicosis.

Polymethylsiloxane polyhydrate does not reduce the absorption of vitamins and microelements, helps to restore disturbed intestinal microflora and does not affect its motor

Name ENG

ENTEROSGEL

Clinical and pharmacological group

Enterosorbent

ATX code

Other intestinal adsorbents

Dosage

70g / 100g x 225g

Structure

polymethylsiloxane polyhydrate (product of nonlinear polycondensation of 1,1,3,3-tetrahydroxy-1,3-dimethyldisiloxane polyhydrate).

auxiliary substances: purified water - 30 g

Indications

In adults and children, as a detoxifying agent:

acute and chronic intoxication of various origins

acute poisoning with potent and poisonous substances (including drugs, alcohol, alkaloids, heavy metal salts)

acute intestinal infections of any genesis as part of complex therapy (including toxic infections, salmonellosis, dysentery, diarrheal syndrome of non-infectious origin, dysbiosis)

purulent-septic diseases, accompanied by severe intoxication, as part of complex therapy

food and drug allergies

hyperbilirubinemia (viral hepatitis)

hyperazotemia (chronic renal failure)

prevention of chronic intoxication among workers in hazardous industries (professional intoxication with polytropic chemical agents, xenobiotics, incorporated radionuclides, compounds of lead, mercury, arsenic, petroleum products, organic solvents, nitrogen oxides, carbon, fluorides, heavy metal salts).

Contraindications

individual intolerance to the drug

intestinal atony.

INN / Active ingredient

Polymethylsiloxane polyhydrate

Storage conditions and periods

At a temperature of 4-30 degrees.

Expiration date: 3 years

Specifications

Category

Enterosorbents and antidotes

,

Diarrhea

,

Preparations for the gastrointestinal tract

Scope of the drug

Gastrointestinal tract

Release form

Paste

Manufacturer country

Russia

Package quantity, pcs

one

Scope of application

Gastroenterology

,

Allergology

Minimum age from

From birth

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Silma

The amount of the dosage form in the primary package

225 g

Primary packaging type

Tuba

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Enterosorbent agent

Anatomical and therapeutic characteristics

A07B Absorbent intestinal preparations

Dosage form

Oral paste

Dosage (volume) of the substance in the preparation

225 g

The target audience

Children

Expiration date in days

1095

Package weight, g

260

Mode of application

:

Inside, 1-2 hours before meals or other drugs, with water. It is recommended to take it with water or dilute the dose in half a glass of water before taking it. Dosage for adults - 1 package or 22.5 g (1.5 tablespoons) 3 times a day. The daily dose is 67.5 g (3 packets) children aged 5 to 14 years old - 15 g (1 tablespoon) 3 times a day. The daily dose is 45 g (2 packets) up to 5 years - 7.5 g (0.5 tablespoons) 3 times a day. The daily dose is 22.5 g (1 packet). It is recommended for infants to stir 2.5 g (0.5 teaspoons) of the drug in a triple volume of breast milk or water and give before each feeding (6 times a day). For the prevention of chronic intoxication - one packet or 1.5 tablespoons (22.5 g) 2 times a day for 7-10 days, monthly. Application for acute diarrhea: adults and children from 5 years of age: initial dose - 2 bags or 45 g (3 tbsp.spoons) for adults and 1 packet or 22.5 g (1.5 tablespoons) for children, then take 1 packet or 22.5 g (1.5 tablespoons) after each act of defecation in case of loose stools ... Children under 5 years of age: the initial dose is 1 tablespoon (15 g), then take 1.5 tsp (7.5 g) after each act of defecation in case of loose stools. After stopping diarrhea, take the drug for 5 days at usual dosages. In case of severe intoxication during the first three days, the dose of the drug can be doubled. The duration of treatment for acute poisoning is 3-5 days, for chronic intoxications and allergic conditions - 2-3 weeks. A second course - on the recommendation of a doctor.the initial dose is 1 tablespoon (15 g), then take 1.5 teaspoons (7.5 g) after each act of defecation in case of loose stools. After stopping diarrhea, take the drug for 5 days at usual dosages. In case of severe intoxication during the first three days, the dose of the drug can be doubled. The duration of treatment for acute poisoning is 3-5 days, for chronic intoxications and allergic conditions - 2-3 weeks. A second course - on the recommendation of a doctor.the initial dose is 1 tablespoon (15 g), then take 1.5 teaspoons (7.5 g) after each act of defecation in case of loose stools. After stopping diarrhea, take the drug for 5 days at usual dosages. In case of severe intoxication during the first three days, the dose of the drug can be doubled. The duration of treatment for acute poisoning is 3-5 days, for chronic intoxications and allergic conditions - 2-3 weeks. A second course - on the recommendation of a doctor.for chronic intoxications and allergic conditions - 2-3 weeks. A second course - on the recommendation of a doctor.for chronic intoxications and allergic conditions - 2-3 weeks. A second course - on the recommendation of a doctor.

Information on technical characteristics, delivery set, country of manufacture "