Enerion coated tablets 200mg No. 60

Release form

Film-coated tablets

Packaging

60 pcs.

pharmachologic effect

Enerion is a synthetic compound similar in structure to thiamine, in comparison with which the molecule has an open thiazole ring, an additional disulfide bond, and a lipophilic ester.

Thanks to this modification, sulbutiamine is highly soluble in fats, is rapidly absorbed from the gastrointestinal tract and easily penetrates the BBB

unlike thiamine, it is able to accumulate in the cells of the reticular formation, hippocampus and dentate gyrus, as well as Purkinje cells and glomeruli of the granular layer of the cerebellar cortex.

Against the background of Enerion's intake, coordination of movement improves and resistance to physical exertion increases, the resistance of the structures of the cerebral cortex to repeated anoxia increases.

The drug is effective in the symptomatic treatment of functional asthenia.

Pharmacokinetics

Sulbutiamine is rapidly absorbed, Cmax of the drug in the blood plasma is reached within 1�2 hours after administration.

T1 / 2 - about 5 hours.

The drug is excreted in the urine.

Indications

Symptomatic treatment of functional asthenia.

Contraindications

Hypersensitivity to any component of Enerion.

With caution: persons under 18 years of age (the drug is not recommended due to the lack of clinical data).

Application during pregnancy and lactation

According to the results of clinical studies, the drug does not affect the development of the fetus.

However, due to the lack of sufficient clinical data, Enerion is not recommended to be taken during pregnancy, as well as during breastfeeding, because

it is currently unknown whether sulbutiamine is able to pass into breast milk.

special instructions

The excipients of Enerion's preparation include lactose monohydrate.

As a result, this drug is not recommended for people with lactose deficiency, galactosemia or glucose / galactose malabsorption syndrome.

Impact on the ability to drive a car and perform work requiring a high speed of psychomotor reactions.

Does not affect.

Structure

1 coated tablet contains:

active substance: sulbutiamine 200 mg,

excipients: corn starch - 12 mg

dried starch paste - 40 mg

glucose (dextrose) anhydrous - 20 mg

lactose monohydrate - 65.5 mg

magnesium stearate - 3.5 mg

talc - 9 mg,

shell: sodium bicarbonate - 0.603 mg

sodium carboxymethyl cellulose - 0.556 mg

white beeswax - 0.201 mg

titanium dioxide (E171) - 8.43 mg

ethyl cellulose - 0.485 mg

Sunset" yellow (Sunset yellow FCF, E110) - 3 mg

glycerol monooleate - 0.242 mg

polysorbate 80 - 0.302 mg

povidone - 0.692 mg

sucrose - 106.956 mg

anhydrous colloidal silicon dioxide (Aerosil 130) - 0.404 mg, talc - 28.21 mg

Method of administration and dosage

Inside.

Enerion is recommended for use only in adult patients.

The daily dose is 2-3 tablets (400-600 mg) in 2 divided doses (during breakfast and lunch).

The duration of treatment should not exceed 4 weeks.

Side effects

Allergic reactions (the presence in the composition of the dye "Sunset" yellow), digestive disorders, neuropsychiatric reactions (tremor, headache, agitation, general malaise).

Overdose

Symptoms: agitation with symptoms of euphoria and tremors of the extremities are transient and do not require special treatment.

Storage conditions

At a temperature not exceeding 25 В° C, out of the reach of children.

Shelf life

3 years.

Active substance

Sulbutiamine

Name ENG

ENERION

Clinical and pharmacological group

A drug that regulates metabolic processes in the central nervous system

ATX code

Sulbutiamine

Dosage

200mg

Structure

1 coated tablet contains: active substance: sulbutiamine 200 mg auxiliary substances: corn starch - 12 mg

dried starch paste - 40 mg

glucose (dextrose) anhydrous - 20 mg

lactose monohydrate - 65.5 mg

magnesium stearate - 3.5 mg

talc - 9 mg, shell: sodium bicarbonate - 0.603 mg

sodium carboxymethyl cellulose - 0.556 mg

white beeswax - 0.201 mg

titanium dioxide (E171) - 8.43 mg

ethyl cellulose - 0.485 mg

"Sunset" yellow (Sunset yellow FCF, E110) - 3 mg

glycerol monooleate - 0.242 mg

polysorbate 80 - 0.302 mg

povidone - 0.692 mg

sucrose - 106.956 mg

anhydrous colloidal silicon dioxide (Aerosil 130) - 0.404 mg, talc - 28.21 mg.

Indications

Symptomatic treatment of functional asthenia

INN / Active ingredient

Sulbutiamine

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

Specifications

Scope of the medicinal product

Neurology, psychiatry

Release form

Tablet

Manufacturer country

France

Package quantity, pcs

60

Scope of application

Neurology

,

Psychiatry

Minimum age from

18 years

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Servier

The amount of the dosage form in the primary package

15 pcs.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

An agent that regulates metabolic processes in the central nervous system

Anatomical and therapeutic characteristics

A11DA02 Sulbutiamine

Dosage form

Film-coated tablets

Packaging

Cardboard box

The target audience

Adult

Expiration date in days

1095

Dosage (volume) of the substance in the preparation

1 tablet contains: sulbutiamine 200 mg

Package weight, g

55

Category

:

Mental strain

,

Memory impairment

,

Neuroprotective agents

,

Nootropic drugs

Mode of application

:

Inside.

The drug Enerion is recommended for use only in adult patients. < br> The daily dose is 2-3 tablets (400-600 mg) in 2 divided doses (with breakfast and lunch).

The duration of treatment should not exceed 4 weeks.

Information on technical characteristics, delivery set, country of manufacture "