Ecofuril 0.2, 5 ml 90 ml bottle suspension for oral administration

Dosage form

Homogeneous yellow suspension with a characteristic odor.

Structure

5 ml of suspension contains:

Active ingredient: nifuroxazide 200.00mg

excipients: maltitol - 350.00 mg, lactulose - 300.00 mg, povidone K-90 - 25.00 mg, xanthan gum - 20.00 mg, banana flavor - 10.00 mg, mstyl parahydroxybsoate - 5.00 mg, sodium citrate dihydrate 0.015 mg, anhydrous citric acid - 0.001 mg, purified water to obtain a suspension of 5.0 ml.

general description

Antimicrobial agent is nitrofuran.

Special conditions

When treating diarrhea concomitantly with nifuroxazide therapy, rehydration therapy is necessary.

Treatment of diarrhea in children under 3 years of age should be carried out under medical supervision.

In the case of bacterial diarrhea with signs of systemic damage (deterioration of the general condition, fever, symptoms of intoxication or infection), you should consult a doctor to resolve questions about the use of antibacterial drugs of systemic action.

If symptoms of a hypersensitivity reaction appear (skin rash and itching, difficulty breathing, shortness of breath), you should stop taking the drug.

Due to the content of methyl parahydroxybenzoate, the drug may cause allergic reactions (possibly delayed).

Drinking alcohol during nifuroxazide therapy is prohibited.

Impact on the ability to drive vehicles and perform work requiring increased concentration of attention and speed of psychomotor reactions

The drug does not adversely affect the ability to drive vehicles and / or other mechanisms.

Drug interactions

The simultaneous use of e with drugs that cause the development of disulfiram-like reactions or inhibit the function of the central nervous system is not recommended.

If you are taking other medications (including over-the-counter medications), consult your doctor before using nifuroxazide.

Pharmacodynamics

Antimicrobial agent derived from nitrofuran.

It blocks the activity of dehydrogenases and inhibits the respiratory chains, the tricarboxylic acid cycle and a number of other biochemical processes in the microbial cell.

Destroys the membrane of a microbial cell, reduces the production of toxins by microorganisms.

Highly active against Campilobactcr jejuni, Escherichia coli, Salmonella spp., Shigella spp., Clostridium perfringens, Vibrio eholerae pathogenic Vibrions and Vibrio parahaemolyticus, Staphylococcus spp.

Weakly sensitive to nifuroxazide: Citrobaeter spp., Enterobacter cloacae and Proteus indologcncs.

Resistant to nifuroxazide: Klebsiella spp., Proteus mirabilis, Providcncia spp., Pseudomonas spp.

Does not disturb the balance of intestinal microflora.

In case of acute bacterial diarrhea, it restores intestinal eubiosis.

When infected with enterotropic viruses, it prevents the development of bacterial superinfection.

Pharmokinetics

After oral administration, nifuroxazide is practically not absorbed from the digestive tract and has its antibacterial effect exclusively in the intestinal lumen.

Nifuroxazide is excreted by the intestines: 20% is unchanged, and the rest of nifuroxazide is chemically altered.

Indications

Acute bacterial diarrhea, proceeding without deterioration of the general condition, fever, intoxication.

Contraindications

hypersensitivity to nifuroxazide, to nitrofuran derivatives, other components of the drug,

pregnancy,

neonatal period (up to 1 month), prematurity.

Carefully

liver disease,

alcoholism,

traumatic brain injury,

diseases of the brain,

lactation period,

children's age (over 1 month).

Application during pregnancy and during breastfeeding

The use of the drug during pregnancy is contraindicated.

During breastfeeding, you should consult your doctor before using the drug.

Overdose

Overdose symptoms are not known.

Treatment is symptomatic.

Side effects

Allergic reactions (skin rash, urticaria, Quincke's edema, anaphylactic shock).

If any of the side effects indicated in the instructions are aggravated, or you notice any other side effects not listed in the instructions, inform your doctor.

Special storage conditions

Do not freeze.

Store the opened bottle for no more than 7 days.

Dosage

200mg / 5ml x 90ml

Indications

Acute bacterial diarrhea, proceeding without deterioration of the general condition, fever, intoxication.

Contraindications

hypersensitivity to nifuroxazide, nitrofuran derivatives, other components of the drug, neonatal period (up to 1 month), prematurity.

With care liver disease, alcoholism, traumatic brain injury, brain disease, lactation period, childhood (over 1 month).

Storage conditions and periods

In a dark place at a temperature not exceeding 25 degrees.

(do not freeze).

Expiration date: 2 years (no more than 7 days after opening)

INN / Active ingredient

Nifuroxazide

Specifications

Category

Diarrhea

Scope of the drug

Gastrointestinal tract

Release form

Oral suspension

Manufacturer country

Russia

Package quantity, pcs

one

Vacation conditions

Without recipe

Brand name

Avva Rus

Components

double-sided dosing spoon

The amount of the dosage form in the primary package

90 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antimicrobial agent - nitrofuran

Anatomical and therapeutic characteristics

A07AX03 Nifuroxazide

Dosage form

Suspension for oral administration

Expiration date in days

730

Package weight, g

175

Information on technical characteristics, delivery set, country of manufacture