Dirofen suspension 60 for dogs large breeds Api-San 6 pcs. (fenbendazole, pyrantel)
Special Price
$25.74
Regular Price
$26.00
In stock
SKU
florida948402
Pharmacological action
Dirofen tablets are a combination anthelmintic drug.
The combination of praziquantel, febantel and pyrantel pamoate, which are part of the drug, provides a wide range of its anthelmintic effects on all phases of the development of round and ribbon helminths, parasitizing in the gastrointestinal tract in dogs and cats, including Tohosara sanis, Tohosara mystax, Toxascaris leonina, Uncinaria stenocephala, Trichuris vulpis, Ancylostoma caninum, Echinococcus granulosus, Alveococcus multilocularis, Mesocestoides lineatus, Dipylidium caninum, Diphyllobothrium latum, Multiceps multiceps.
Pyrantela pamoate is a compound of the pyrimidine group, its mechanism of action is based on the blockade of transmission of nerve impulses in the neuromuscular synapses by depolarization of the membranes of muscle cells, which causes paralysis of the muscular system of pyrantel nematodes is poorly absorbed, which ensures its prolonged effect on helminths in the intestine is excreted from the body mainly unchanged (93%) with feces.
Praziquantel is a compound of the pyrazinisoquinoline group, which is active against gastrointestinal cestodes at all phases of development. Increasing the permeability of the parasite’s cell membranes for calcium ions (Ca2 +), it causes membrane depolarization, muscle contraction and the destruction of the tegument, which leads to the death of helminths and helps them to be excreted from the animal’s body. The compound is rapidly absorbed in the gastrointestinal tract, reaching a maximum concentration in blood plasma after 1-3 hours, reversibly binds to blood serum proteins (70-80%), is partially metabolized in the liver, re-secreted into the intestines, excreted mainly in the urine (up to 80%) within 24 hours.
Febantel refers to probenzimidazoles that are biotransformed in the body into benzimidazoles. The mechanism of action of febantel is based on the inhibition of the enzyme fumarate reductase in helminth mitochondria, as a result of which glucose uptake and protein synthesis of tubulin are disrupted, which leads to the destruction of the microtubular apparatus of the parasite cells, causing its death. Febantel is absorbed in the intestine, metabolized in the liver and excreted with bile into the intestinal lumen, where its re-resorption is partially noted, excreted from the body both in unchanged form and in the form of several metabolites with feces and urine.
Dirofen tablets by their degree of exposure to the body belong to low-hazard substances (hazard class 4 according to GOST 12.1.007-76), in the recommended doses it does not have an embryotoxic, teratogenic and sensitizing effect, well tolerated by dogs and cats of different breeds and ages. Buy Dirofen suspension 60 for dogs large breeds Api-San 6 pcs. (fenbendazole, pyrantel) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Dirofen tablets are a combination anthelmintic drug.
The combination of praziquantel, febantel and pyrantel pamoate, which are part of the drug, provides a wide range of its anthelmintic effects on all phases of the development of round and ribbon helminths, parasitizing in the gastrointestinal tract in dogs and cats, including Tohosara sanis, Tohosara mystax, Toxascaris leonina, Uncinaria stenocephala, Trichuris vulpis, Ancylostoma caninum, Echinococcus granulosus, Alveococcus multilocularis, Mesocestoides lineatus, Dipylidium caninum, Diphyllobothrium latum, Multiceps multiceps.
Pyrantela pamoate is a compound of the pyrimidine group, its mechanism of action is based on the blockade of transmission of nerve impulses in the neuromuscular synapses by depolarization of the membranes of muscle cells, which causes paralysis of the muscular system of pyrantel nematodes is poorly absorbed, which ensures its prolonged effect on helminths in the intestine is excreted from the body mainly unchanged (93%) with feces.
Praziquantel is a compound of the pyrazinisoquinoline group, which is active against gastrointestinal cestodes at all phases of development. Increasing the permeability of the parasite’s cell membranes for calcium ions (Ca2 +), it causes membrane depolarization, muscle contraction and the destruction of the tegument, which leads to the death of helminths and helps them to be excreted from the animal’s body. The compound is rapidly absorbed in the gastrointestinal tract, reaching a maximum concentration in blood plasma after 1-3 hours, reversibly binds to blood serum proteins (70-80%), is partially metabolized in the liver, re-secreted into the intestines, excreted mainly in the urine (up to 80%) within 24 hours.
Febantel refers to probenzimidazoles that are biotransformed in the body into benzimidazoles. The mechanism of action of febantel is based on the inhibition of the enzyme fumarate reductase in helminth mitochondria, as a result of which glucose uptake and protein synthesis of tubulin are disrupted, which leads to the destruction of the microtubular apparatus of the parasite cells, causing its death. Febantel is absorbed in the intestine, metabolized in the liver and excreted with bile into the intestinal lumen, where its re-resorption is partially noted, excreted from the body both in unchanged form and in the form of several metabolites with feces and urine.
Dirofen tablets by their degree of exposure to the body belong to low-hazard substances (hazard class 4 according to GOST 12.1.007-76), in the recommended doses it does not have an embryotoxic, teratogenic and sensitizing effect, well tolerated by dogs and cats of different breeds and ages. Buy Dirofen suspension 60 for dogs large breeds Api-San 6 pcs. (fenbendazole, pyrantel) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Pharmacological action
Dirofen tablets are a combination anthelmintic drug.
The combination of praziquantel, febantel and pyrantel pamoate, which are part of the drug, provides a wide range of its anthelmintic effects on all phases of the development of round and ribbon helminths, parasitizing in the gastrointestinal tract in dogs and cats, including Tohosara sanis, Tohosara mystax, Toxascaris leonina, Uncinaria stenocephala, Trichuris vulpis, Ancylostoma caninum, Echinococcus granulosus, Alveococcus multilocularis, Mesocestoides lineatus, Dipylidium caninum, Diphyllobothrium latum, Multiceps multiceps.
Pyrantela pamoate is a compound of the pyrimidine group, its mechanism of action is based on the blockade of transmission of nerve impulses in the neuromuscular synapses by depolarization of the membranes of muscle cells, which causes paralysis of the muscular system of pyrantel nematodes is poorly absorbed, which ensures its prolonged effect on helminths in the intestine is excreted from the body mainly unchanged (93%) with feces.
Praziquantel is a compound of the pyrazinisoquinoline group, which is active against gastrointestinal cestodes at all phases of development. Increasing the permeability of the parasite’s cell membranes for calcium ions (Ca2 +), it causes membrane depolarization, muscle contraction and the destruction of the tegument, which leads to the death of helminths and helps them to be excreted from the animal’s body. The compound is rapidly absorbed in the gastrointestinal tract, reaching a maximum concentration in blood plasma after 1-3 hours, reversibly binds to blood serum proteins (70-80%), is partially metabolized in the liver, re-secreted into the intestines, excreted mainly in the urine (up to 80%) within 24 hours.
Febantel refers to probenzimidazoles that are biotransformed in the body into benzimidazoles. The mechanism of action of febantel is based on the inhibition of the enzyme fumarate reductase in helminth mitochondria, as a result of which glucose uptake and protein synthesis of tubulin are disrupted, which leads to the destruction of the microtubular apparatus of the parasite cells, causing its death. Febantel is absorbed in the intestine, metabolized in the liver and excreted with bile into the intestinal lumen, where its re-resorption is partially noted, excreted from the body both in unchanged form and in the form of several metabolites with feces and urine.
Dirofen tablets by their degree of exposure to the body belong to low-hazard substances (hazard class 4 according to GOST 12.1.007-76), in the recommended doses it does not have an embryotoxic, teratogenic and sensitizing effect, well tolerated by dogs and cats of different breeds and ages.
Indications
Dirofen tablets are prescribed to cats and dogs from 3 weeks of age for prophylactic and therapeutic purposes with nematodoses (toxocariasis, toxascaridosis, uncinariosis, trichocephalosis, ankylostomy), cestodoses (tenidiosis, diphycidioidosis, diokyloidosis, diokyloidiosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, and cestodose infestations.
Contraindications
Contraindication to use is individual intolerance to the components of the drug (including a history). Dirofen Plus should not be used in females in the first half of pregnancy, exhausted, sick with infectious diseases and recovering animals.
Composition
Pyrantela pamoate - 300 mg / tab, febantel - 300 mg / tab, praziquantel - 100 mg / tab, excipients up to 1 mg.
dosage form
tablets
Dirofen suspension 60 for dogs large breeds Api-San 6 pcs. (fenbendazole, pyrantel) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Dirofen suspension 60 for dogs large breeds Api-San 6 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.
Dirofen tablets are a combination anthelmintic drug.
The combination of praziquantel, febantel and pyrantel pamoate, which are part of the drug, provides a wide range of its anthelmintic effects on all phases of the development of round and ribbon helminths, parasitizing in the gastrointestinal tract in dogs and cats, including Tohosara sanis, Tohosara mystax, Toxascaris leonina, Uncinaria stenocephala, Trichuris vulpis, Ancylostoma caninum, Echinococcus granulosus, Alveococcus multilocularis, Mesocestoides lineatus, Dipylidium caninum, Diphyllobothrium latum, Multiceps multiceps.
Pyrantela pamoate is a compound of the pyrimidine group, its mechanism of action is based on the blockade of transmission of nerve impulses in the neuromuscular synapses by depolarization of the membranes of muscle cells, which causes paralysis of the muscular system of pyrantel nematodes is poorly absorbed, which ensures its prolonged effect on helminths in the intestine is excreted from the body mainly unchanged (93%) with feces.
Praziquantel is a compound of the pyrazinisoquinoline group, which is active against gastrointestinal cestodes at all phases of development. Increasing the permeability of the parasite’s cell membranes for calcium ions (Ca2 +), it causes membrane depolarization, muscle contraction and the destruction of the tegument, which leads to the death of helminths and helps them to be excreted from the animal’s body. The compound is rapidly absorbed in the gastrointestinal tract, reaching a maximum concentration in blood plasma after 1-3 hours, reversibly binds to blood serum proteins (70-80%), is partially metabolized in the liver, re-secreted into the intestines, excreted mainly in the urine (up to 80%) within 24 hours.
Febantel refers to probenzimidazoles that are biotransformed in the body into benzimidazoles. The mechanism of action of febantel is based on the inhibition of the enzyme fumarate reductase in helminth mitochondria, as a result of which glucose uptake and protein synthesis of tubulin are disrupted, which leads to the destruction of the microtubular apparatus of the parasite cells, causing its death. Febantel is absorbed in the intestine, metabolized in the liver and excreted with bile into the intestinal lumen, where its re-resorption is partially noted, excreted from the body both in unchanged form and in the form of several metabolites with feces and urine.
Dirofen tablets by their degree of exposure to the body belong to low-hazard substances (hazard class 4 according to GOST 12.1.007-76), in the recommended doses it does not have an embryotoxic, teratogenic and sensitizing effect, well tolerated by dogs and cats of different breeds and ages.
Indications
Dirofen tablets are prescribed to cats and dogs from 3 weeks of age for prophylactic and therapeutic purposes with nematodoses (toxocariasis, toxascaridosis, uncinariosis, trichocephalosis, ankylostomy), cestodoses (tenidiosis, diphycidioidosis, diokyloidosis, diokyloidiosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, diokyloidosis, and cestodose infestations.
Contraindications
Contraindication to use is individual intolerance to the components of the drug (including a history). Dirofen Plus should not be used in females in the first half of pregnancy, exhausted, sick with infectious diseases and recovering animals.
Composition
Pyrantela pamoate - 300 mg / tab, febantel - 300 mg / tab, praziquantel - 100 mg / tab, excipients up to 1 mg.
dosage form
tablets
Dirofen suspension 60 for dogs large breeds Api-San 6 pcs. (fenbendazole, pyrantel) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Dirofen suspension 60 for dogs large breeds Api-San 6 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.
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