Differin® cream for external use 0.1%, 30g

DifferinВ® is a drug for the treatment of comedonal acne (acne) and maintenance therapy for acne

The active substance (adapalene 0.1%) has:

Comedolytic action

Anti-comedogenic action

Anti-inflammatory action

Normalizes the processes of keratinization

DifferinВ®

Helps fight acne and comedones (white and blackheads) 1

Promotes the renewal of skin cells

DifferinВ® is not an antibiotic and does not cause antibacterial resistance, therefore it can be used for long courses

DifferinВ® can be used to treat acne both in monotherapy and in combination with other local or systemic drugs (antibiotics, oral antiandrogens)

The drug DifferinВ® is applied in a thin layer to the affected areas of the skin once a day before going to bed on clean, dry skin, avoiding the contact of the gel in the eyes and lips.

The therapeutic effect develops after 4-8 weeks of therapy, persistent improvement after 3 months of treatment.

During the period of use of the drug, active exposure to the sun and UV radiation should be avoided (UV radiation is not recommended for epidermis regeneration)

DifferinВ® cream is suitable for sensitive, dry skin, and DifferinВ® gel is suitable for oily skin2

1. Instructions for the use of the drug DifferinВ®

2. Kruglova L.S., Ikonnikova E.V.

Results of an open comparative study of the efficacy and tolerability of therapy with two dosage forms of adapalene, Clinical Dermatology and Venereology 2018, vol. 17, No. 5, 70-78

Name ENG

DIFFERIN

Clinical and pharmacological group

Acne rash treatment

ATX code

Adapalene

Dosage

0.001

Structure

1 gram of cream contains: Active ingredient: Adapalene - 1.0 mg.

Excipients: carbomer 974R (934R) - 4.5 mg, macrogol methyldextrose sesquistearate - 35.0 mg, glycerol - 30.0 mg, natural squalane - 60.0 mg, methyldextrose sesquistearate - 35.0 mg, disodium edetate - 1 , 0 mg, methyl parahydroxybenzoate - 2.0 mg, propyl parahydroxybenzoate - 1.0 mg, phenoxyethanol - 5.0 mg, cyclomethicone - 130.0 mg, sodium hydroxide - up to pH 6.5 В± 0.15, purified water - up to 1 g.

Indications

Acne

Storage conditions and periods

At a temperature not higher than 25 В° C.

Do not freeze.

Keep out of the reach of children

INN / Active ingredient

Adapalen

Contraindications

- Hypersensitivity to adapalene or any of the excipients

- Children under 12 years of age (the effectiveness and safety of the drug for this age category has not been established)

Specifications

Category

Acne

Scope of the medicinal product

Dermatology

Release form

Cream

Manufacturer country

France

Package quantity, pcs

one

Scope of application

Dermatology

Minimum age from

12 years

Way of introduction

On the skin

Indications for the use of ICD-10

L70 Acne

Vacation conditions

Without recipe

Brand name

Galderma

The amount of the dosage form in the primary package

30 g

Primary packaging type

Tuba

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Acne rash treatment

Anatomical and therapeutic characteristics

D10AD03 Adapalen

Dosage form

Cream for external use

Packaging

Box

The target audience

Children

Expiration date in days

1095

Dosage (volume) of the substance in the preparation

adapalene 1 mg

Package weight, g

thirty

Mode of application

:

For external use only.

3 The cream should be applied in a thin layer to acne-affected areas of the skin once a day before going to bed on clean, dry skin, avoiding getting the cream in the eyes, on the lips, mucous membranes and the corners of the nose.

A noticeable clinical improvement develops after 4-8 weeks of treatment, persistent improvement after a 3-month course of treatment.

Since the alternation of therapy methods is adopted in the treatment of acne, after 3 months of drug therapy, it is recommended to consult a doctor about further therapy.