Dayvonex ointment for outdoor use. approx. 0.005% 30g tube

Special Price $57.42 Regular Price $58.00
In stock
SKU
FL102027769
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Category

Psoriasis

Scope of the drug

Leather

Release form

Ointment

Manufacturer country

Ireland

Package quantity, pcs

one

Description

Latin name daivonex Release form Ointment for external use. Packing Tube 30 g. Pharmacological action Pharmacodynamics A drug for the treatment of psoriasis. Calcipotriol is a synthetic analogue of the active metabolite of vitamin D, stimulates morphological differentiation and suppresses the proliferation of keratinocytes, which underlies its therapeutic effect in psoriasis. Calcipotriol is a potent inhibitor of T-lymphocyte activation caused by interleukin I. The effect of calcipotriol on calcium metabolism is 100 times weaker than that of vitamin D3. Pharmacokinetics Transdermal absorption of calcipotriol is, depending on the dose used, from 1% to 5%. Calcipotriol undergoes rapid biotransformation in the liver with the formation of pharmacologically inactive metabolites. T 1/2 is very short. Compositional analogues of Rocaltrol capsules 0.25 mcg,30 pcs. Hoffmann la Roche Switzerland 659 RUR Indications Vulgar psoriasis, incl. chronic psoriasis of the scalp. Contraindications Hypersensitivity to drug components. Diseases accompanied by impaired calcium metabolism. The drug should be used with caution in case of: hypercalcemia, hypercalciuria, hypervitaminosis D, nephrolithiasis. In children due to lack of experience in use. In patients over 65 years of age. Application during pregnancy and lactation The safety of the drug during pregnancy and lactation has not been established. It is not known whether calcipotriol is excreted in breast milk. Special instructions It is not recommended to apply the ointment to the skin of the face. To avoid contact of the drug with the skin of the face, hands should be thoroughly washed after each use of the ointment.Hypercalcemia develops when the maximum dose of calcipotriol per week is exceeded. When the drug is discontinued, the calcium concentration in the blood quickly returns to normal. Daivonex treatment can be combined with PUVA therapy. Influence on the ability to drive vehicles and other mechanisms requiring increased concentration of attention Daivonex does not affect the ability to drive vehicles and control mechanisms. Composition 1 g of ointment for external use contains: Active substance: calcipotriol 50 mcg. Excipients: disodium edetate, sodium hydrogen phosphate, ОІ-tocopherol, liquid paraffin, polyethylene glycol stearate, propylene glycol, white paraffin, water. Dosage and administration The ointment is applied in a thin layer to the affected skin 2 times / day. The therapeutic effect is usually observed within 1-2 weeks from the start of treatment.The duration of the course of treatment is no more than 6-8 weeks. For adults: the maximum daily dose is 15 g, the maximum dose per week is no more than 100 g. For children over 12 years old: the maximum dose per week is 75 g. For children aged 6 to 12 years: the maximum dose per week - no more than 50 g. Side effects Dermatological reactions: possible - local skin irritation, erythema and itching of the skin rarely - dermatitis, exacerbation of psoriasis in some cases - hyperpigmentation, photosensitivity. From the side of metabolism: hypercalciuria, hypercalcemia. Drug interactions Dayvonex should not be used concurrently with topical preparations containing salicylic acid. Overdose Symptoms: when using the drug in doses higher than recommended,an increase in the concentration of calcium in the blood is possible. Treatment: drug withdrawal. Storage conditions Store at a temperature not exceeding 25 В° РЎ. Keep out of the reach of children. Shelf life 2 years. Active ingredient Calcipotriol

Name ENG

Daivonex

Clinical and pharmacological group

An antiproliferative drug for the treatment of psoriasis

ATX code

Calcipotriol

Dosage

0.005% x 30g

Structure

1 g of ointment for external use contains: Active substance: calcipotriol 50 mcg.

Excipients: disodium edetate, sodium hydrogen phosphate, ОІ-tocopherol, liquid paraffin, polyethylene glycol stearate, propylene glycol, white paraffin, water.

Indications

Vulgar psoriasis, incl.

chronic psoriasis of the scalp.

Contraindications

Hypersensitivity to drug components.

Diseases accompanied by impaired calcium metabolism.

The drug should be used with caution when: hypercalcemia, hypercalciuria, hypervitaminosis D, nephrolithiasis.

In children due to lack of experience in use.

In patients over 65.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 2 years

after opening - 6 months

INN / Active ingredient

Calcipotriol

Specifications

Category

Psoriasis

Scope of the drug

Leather

Release form

Ointment

Manufacturer country

Ireland

Package quantity, pcs

one

Way of introduction

Outwardly

Vacation conditions

Without recipe

Brand name

Leo Pharmaceutical Products

The amount of the dosage form in the primary package

30 g

Primary packaging type

Tuba

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Psoriasis cure

Anatomical and therapeutic characteristics

D05AX02 Calcipotriol

Dosage form

Ointment for external use

Dosage (volume) of the substance in the preparation

calcipotriol 50 mcg

Expiration date in days

730

Package weight, g

45

Mode of application

:

The ointment is applied in a thin layer to the affected skin 2 times / day.

The therapeutic effect is usually observed within 1-2 weeks from the start of treatment.

The duration of the course of treatment is no more than 6-8 weeks.

For adults: the maximum daily dose is 15 g, the maximum dose per week is no more than 100 g. For children over 12 years old: the maximum dose per week is 75 g. For children aged 6 to 12 years: the maximum dose per week - no more than 50 g.

Information on technical characteristics, delivery set, country of manufacture

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