Clotrimazole-Akrikhin solution for narcotics approx. 1% fl. 15ml

Release form, composition and packaging

Solution for external use 1 ml

clotrimazole 10 mg

15 ml - bottles with a dropper (1) - cardboard packs.

pharmachologic effect

Antifungal agent of the group of imidazole derivatives for topical use.

It acts by disrupting the synthesis of ergosterol, which is an integral part of the cell membrane of fungi.

Possesses a wide spectrum of action.

Active against dermatophytes, molds, fungi of the genus Candida, Malassezia furfur.

Clotrimazole is also active against Corynebacterium minutissimum, Streptococcus spp., Staphylococcus spp., Trichomonas vaginalis.

Pharmacokinetics

When applied externally, clotrimazole penetrates well into various layers of the skin, reaching therapeutic concentrations.

When applied topically, a small amount of clotrimazole is absorbed into the bloodstream.

Indications for use

Fungal lesions of the skin and mucous membranes caused by dermatophytes, mold and yeast-like fungi, versicolor versicolor, erythrasma, vulvovaginal candidiasis, trichomoniasis, mycoses, complicated by secondary pyoderma.

Contraindications for use

Hypersensitivity to clotrimazole, I trimester of pregnancy.

Dosage regimen

When applied externally, apply to the affected skin 2-3 times / day for 2-4 weeks.

When processing the oral cavity, apply 1-2 times / day for no more than 7 days.

Intravaginally - 100-500 mg for 1-6 days.

Side effect

Local reactions: contact allergic dermatitis, redness, burning sensation.

Drug interactions

With simultaneous use with amphotericin B, nystatin, the activity of clotrimazole decreases.

Application during pregnancy and lactation

Contraindicated in the first trimester of pregnancy.

In experimental studies, it was found that when used in high doses, clotrimazole has an embryotoxic effect.

It is not known whether clotrimazole is excreted in breast milk.

Although clotrimazole is not contraindicated during pregnancy and lactation, the potential risk should be considered when choosing antifungal therapy.

special instructions

Dosage forms intended for intravaginal use are not used during menstruation.

To prevent reinfection, simultaneous treatment of sexual partners is necessary.

Clotrimazole is not recommended for use in ophthalmology.

Name ENG

CLOTRIMAZOLE

Clinical and pharmacological group

Topical antifungal agent

ATX code

Clotrimazole

Dosage

1% x 15ml

Structure

clotrimazole

Indications

Fungal lesions of the skin and mucous membranes.

Mycoses of the feet / hands, smooth skin of the trunk, limbs, folds, beard, mustache, scalp, caused by dermatophytes.

Pityriasis versicolor, spectra, candidiasis of the skin, genital mucosa, paronychia.

Contraindications

Hypersensitivity to clotrimazole, I trimester of pregnancy.

INN / Active ingredient

clotrimazole

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

Specifications

Category

Antifungal

Scope of the drug

Gynecology

Release form

Solution

Manufacturer country

Poland

Package quantity, pcs

one

Way of introduction

Vaginally

Vacation conditions

Without recipe

Volume, ml.

15 ml

Brand name

Akrikhin

The amount of the dosage form in the primary package

15 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antifungal agent

Anatomical and therapeutic characteristics

D01AC01 Clotrimazole

Dosage form

Solution for external use

Expiration date in days

1095

Package weight, g

15

Mode of application

:

When applied externally, apply to the affected skin 2-3 times / day for 2-4 weeks.

When processing the oral cavity, apply 1-2 times / day for no more than 7 days.

Intravaginally - 100-500 mg for 1-6 days.

Dosage (volume) of the substance in the preparation

:

100 g clotrimazole 1 g Excipients: propylene glycol - 12.5 g, methyl parahydroxybenzoate (nipagin) - 0.2 g, succinic acid - 0.5 g, sodium benzoate - 6 g, emulsion wax - 3 g, castor oil - 14 g, methyl cellulose - 3 g , monogl