Citramon P tab. # 20 Renewal
Category
Pain relievers
,
Migraine
Scope of the drug
General
Release form
Tablet
Manufacturer country
Russia
Package quantity, pcs
twenty
Release form, composition and packaging
Pills
1 tab.
acetylsalicylic acid
240 mg
paracetamol
180 mg
caffeine
30 mg
10 pieces.
- non-cell contoured packaging (1) - cardboard packs.
10 pieces.
- non-cell contoured packaging (2) - cardboard packs.
10 pieces.
- non-cell contoured packaging (3) - cardboard packs.
10 pieces.
- non-cell contoured packaging (5) - cardboard packs.
10 pieces.
- contour cell packaging (1) - cardboard packs.
10 pieces.
- contour cell packages (2) - cardboard packs.
10 pieces.
- contour cell packages (3) - cardboard packs.
10 pieces.
- contour cell packaging (5) - cardboard packs.
pharmachologic effect
Combined drug.
Acetylsalicylic acid has antipyretic and anti-inflammatory effects, relieves pain, especially caused by the inflammatory process, and also moderately inhibits platelet aggregation and thrombus formation, improves microcirculation in the focus of inflammation.
Caffeine increases the reflex excitability of the spinal cord, stimulates the respiratory and vasomotor centers, dilates the blood vessels of skeletal muscles, brain, heart, kidneys, and reduces platelet aggregation
reduces drowsiness, fatigue, increases mental and physical performance.
In this combination, a small dose of caffeine has practically no stimulating effect on the central nervous system, however, it helps to normalize the tone of the cerebral vessels and accelerate blood flow.
Paracetamol has an analgesic, antipyretic and extremely weak anti-inflammatory effect, which is associated with its effect on the center of thermoregulation in the hypothalamus and a weakly expressed ability to inhibit the synthesis of prostaglandins in peripheral tissues.
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Indications for use
Pain syndrome of mild and moderate severity (of various origins): headache
migraine
toothache
neuralgia
myalgia
arthralgia
algodismenorrhea.
Feverish syndrome: with acute respiratory infections
with the flu.
Contraindications for use
Hypersensitivity to drug components
erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase)
gastrointestinal bleeding
aspirin" asthma
hemophilia
hemorrhagic diathesis
hypoprothrombinemia
portal hypertension
vitamin deficiency K
renal failure
I and III trimesters of pregnancy
lactation period (breastfeeding)
deficiency of glucose-6-phosphate dehydrogenase
severe arterial hypertension
severe course of ischemic heart disease
glaucoma
increased excitability
sleep disorders
surgical interventions accompanied by bleeding
children's age (up to 15 years - the risk of developing Reye's syndrome in children with hyperthermia against the background of viral diseases).
With care: gout, liver disease.
Dosage regimen
Inside (during or after meals) take every 4 hours. On average, take 3-4 times / day.
The maximum frequency of admission is 8 times / day.
The course of treatment is no more than 7-10 days.
In case of impaired renal or liver function, the interval between doses is at least 6 hours.
The drug should not be taken for more than 5 days when prescribed as an anesthetic and more than 3 days as an antipyretic.
Other doses and regimens are determined by the doctor.
Side effect
From the digestive system: gastralgia, nausea, vomiting, hepatotoxicity, erosive and ulcerative lesions of the gastrointestinal tract.
From the urinary system: nephrotoxicity,
Allergic reactions: skin manifestations, Stevens-Johnson syndrome, Lyell's syndrome, bronchospasm.
From the side of the cardiovascular system: tachycardia, increased blood pressure,
With prolonged use: dizziness, headache, visual disturbances, tinnitus, decreased platelet aggregation, hypocoagulation, hemorrhagic syndrome (including nosebleeds, bleeding gums, purpura and), kidney damage with papillary necrosis
deafness
Reye's syndrome in children (hyperpyrexia, metabolic acidosis, disorders of the nervous system and psyche, vomiting, liver dysfunction).
Drug interactions
Strengthens the action of heparin, indirect anticoagulants, reserpine, steroid hormones and hypoglycemic drugs.
Concomitant administration with other NSAIDs, methotrexate increases the risk of side effects.
Reduces the effectiveness of spironolactone, furosemide, antihypertensive drugs, as well as anti-gout drugs that promote the excretion of uric acid.
Barbiturates, rifampicin, salicylamide, antiepileptic drugs and other stimulants of microsomal oxidation contribute to the formation of toxic paracetamol metabolites that affect liver function.
Metoclopramide accelerates the absorption of paracetamol.
Under the influence of paracetamol, T1 / 2 of chloramphenicol increases by 5 times.
With repeated administration, paracetamol can enhance the effect of anticoagulants (dicoumarin derivatives).
The simultaneous use of paracetamol and ethanol increases the risk of developing hepatotoxic effects.
Caffeine accelerates the absorption of ergotamine.
Application during pregnancy and lactation
Use is contraindicated in the I and III trimesters of pregnancy and during lactation (breastfeeding).
Acetylsalicylic acid has a teratogenic effect
when used in the first trimester of pregnancy, it leads to a developmental defect - splitting of the upper palate
in the third trimester - to inhibition of labor (inhibition of prostaglandin synthesis), to the closure of the ductus arteriosus in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the pulmonary circulation.
It is excreted in breast milk, which increases the risk of bleeding in a child due to impaired platelet function.
Special instructions Children should not be prescribed medicines containing acetylsalicylic acid, since in the case of a viral infection, they can increase the risk of Reye's syndrome.
Symptoms of Reye's syndrome are prolonged vomiting, acute encephalopathy, and enlarged liver.
With prolonged use of the drug, it is necessary to monitor the peripheral blood and the functional state of the liver.
Since acetylsalicylic acid slows down blood clotting, the patient, if he is to undergo surgery, must warn the doctor in advance about taking the drug.
Patients with hypersensitivity or with asthmatic reactions to salicylates or their derivatives, acetylsalicylic acid can only be prescribed with special precautions (in an emergency room).
Acetylsalicylic acid in low doses reduces the excretion of uric acid.
In patients with a corresponding predisposition, this can in some cases provoke an attack of gout.
During treatment, you should stop using ethanol (increased risk of gastrointestinal bleeding).
Name ENG
CITRAMON P
Clinical and pharmacological group
Combined analgesic-antipyretic.
ATX code
Acetylsalicylic acid in combination with psycholeptics.
Dosage
240mg + 30mg + 180mg
Structure
1 tab.
acetylsalicylic acid 240 mg
paracetamol 180 mg
caffeine (in terms of monohydrate) 30 mg. Excipients: cocoa powder - 22.5 mg, citric acid monohydrate - 5 mg, potato starch - 64.2 mg, talc - 4.9 mg, calcium stearate - 2.8 mg, polysorbate 80 - 0.6 mg.
Indications
Pain syndrome of mild and moderate severity (of various origins): headache
migraine
toothache
neuralgia
myalgia
arthralgia
algodismenorrhea.
Feverish syndrome: with acute respiratory infections
with the flu.
INN / Active ingredient
Caffeine + Paracetamol + Acetylsalicylic Acid
Contraindications
Hypersensitivity to drug components
erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase)
gastrointestinal bleeding
"aspirin" asthma
hemophilia
hemorrhagic diathesis
hypoprothrombinemia
portal hypertension
vitamin deficiency K
renal failure
I and III trimesters of pregnancy
lactation period (breastfeeding)
deficiency of glucose-6-phosphate dehydrogenase
severe arterial hypertension
severe course of ischemic heart disease
glaucoma
increased excitability
sleep disorders
surgical interventions accompanied by bleeding
children's age (up to 15 years - the risk of developing Reye's syndrome in children with hyperthermia against the background of viral diseases).
With care: gout, liver disease.
Storage conditions and periods
In a dry place, at a temperature not exceeding 25 degrees.
Expiration date: 4 years
Specifications
Category
Pain relievers
,
Migraine
Scope of the drug
General
Release form
Tablet
Manufacturer country
Russia
Package quantity, pcs
twenty
Way of introduction
Through the mouth
Vacation conditions
Without recipe
Brand name
Renewal
The amount of the dosage form in the primary package
10 pieces.
Primary packaging type
Blister
Type of consumer packaging
Pack of cardboard
Dosage form
Pills
Expiration date in days
1460
Package weight, g
thirty
Mode of application
:
Inside (during or after meals), 1 tab.
every 4 hours, with pain, 1-2 tab.
the average daily dose is 3-4 tablets, the maximum daily dose is 8 tablets.
The use of the drug is not more than 7-10 days. < br> < br> To reduce the irritating effect on the gastrointestinal tract, take the tablet with milk or alkaline mineral water.
In case of impaired renal or liver function, the interval between doses is at least 6 hours.
The drug should not be taken for more than 5 days when prescribed as an anesthetic and more than 3 days as an antipyretic.
Other doses and regimens are determined by the doctor.
Pharmaco-therapeutic group
:
Combined analgesic agent (NSAIDs + non-narcotic analgesic agent + psychostimulating agent)
Anatomical and therapeutic characteristics
:
N02BA71 Acetylsalicylic acid, in combination with psychotropic drugs
Dosage (volume) of the substance in the preparation
:
acetylsalicylic acid 240 mg, paracetamol 180 mg, caffeine 30 mg
Information on technical characteristics, delivery set, country of manufacture "