Details

Description

Release form

Gel for external use.

Packaging

100 g

pharmachologic effect

Pharmacodynamics

NSAID, a derivative of propionic acid.

It has an analgesic, anti-inflammatory effect.

By inhibiting COX-1 and COX-2, it inhibits the synthesis of prostaglandins.

It has anti-bradykinin activity, stabilizes lysosomal membranes.

Reduces the release of cytokines, inhibits the activity of neutrophils.

With articular syndrome, it relieves joint pain at rest and during movement, reduces morning stiffness and swelling of the joints, and helps to increase the range of motion.

Pharmacokinetics

Suction

When applied externally, the gel is extremely slow transdermal absorption of ketoprofen, which ensures that its concentration in the inflamed tissues is maintained within the therapeutic level for a long time.

Absorption into the systemic circulation is negligible.

Practically does not cumulate.

The bioavailability of the gel is about 5%.

Distribution

Ketoprofen penetrates well into synovial fluid and connective tissue.

Indications

Inflammatory or traumatic lesions of joints, tendons, ligaments and muscles:

arthritis, periarthritis

tendinitis, tendosynovitis

bursitis

bruises, injuries of ligaments, dislocations, injuries of the knee meniscus

torticollis

lumbago.

Phlebitis, periphlebitis.

Contraindications

Hypersensitivity to ketoprofen or other components of the drug

dermatoses

eczema

infected abrasions and wounds

pregnancy and lactation period

childhood.

Application during pregnancy and lactation

The drug is contraindicated for use during pregnancy and lactation.

special instructions

It is not recommended to apply the gel to open wounds or damaged skin areas.

Do not allow the gel to come into contact with mucous membranes and eyes.

Structure

1 g of gel contains:

Active ingredients: ketoprofen 25 mg.

Excipients: rectified ethanol (ethyl alcohol), nipagin, carbomer, trometamol, lavender oil, neroli oil, purified water.

Method of administration and dosage

The drug is applied to the skin of the painful area 2 times / day, squeezing out from the tube about 3-5 cm of gel or more (depending on the area of вЂ�вЂ�the painful area), spread in a uniform thin layer and gently rub in until complete absorption.

In order to increase the effectiveness of therapy, it is possible to apply the gel under a dry occlusive dressing.

Side effects

In isolated cases: allergic reactions that require discontinuation of the drug, photosensitivity.

Drug interactions

Currently, no cases of drug interaction between Bystrumgel and other drugs have been identified.

Overdose

Overdose cases when using the drug Bystrumgel are not described.

Storage conditions

Store in a dry, dark place, out of reach of children, at a temperature of 15 В° to 25 В° C

Shelf life

2 years.

Active substance

Ketoprofen

Name ENG

BYSTRUMGEL

Clinical and pharmacological group

NSAIDs for external use

ATX code

Ketoprofen

Dosage

2.5% x 100g

Structure

1 g of gel contains: Active ingredients: ketoprofen 25 mg.

Excipients: rectified ethanol (ethyl alcohol), nipagin, carbomer, trometamol, lavender oil, neroli oil, purified water

Storage conditions and periods

At a temperature of 15-25 degrees.

Expiration date: 2 years

INN / Active ingredient

ketoprofen

Specifications