Buscopan rectal suppositories 10 mg, 10 pcs. (Hyostsyna butylbromide)

Latin name

Buscopan

Release form

Rectal suppositories.



packaging 10 pcs 10 mg each.

Pharmacological action

Blocker of m-cholinergic receptors.

It has a local antispasmodic effect on the smooth muscles of the internal organs (gastrointestinal tract, biliary tract, urinary tract), reduces the secretion of digestive glands.

Local antispasmodic effect due to ganglion-blocking and m-anticholinergic activity of the drug.

Being a quaternary ammonium derivative, hyoscine butyl bromide does not penetrate the BBB, therefore there is no anticholinergic effect on the central nervous system.

Indications

renal colic

biliary colic

spastic dyskinesia of the biliary tract and gallbladder

cholecystitis

intestinal colic

pyloric spasm of the gastric ulcer

Contraindications

hypersensitivity to hyoscine-N-butyl bromide or any other component of the

preparation angle-closure glaucoma

myasthenia

megacolon

pulmonary edema

severe cerebral atherosclerosis.

Use during pregnancy and lactation

There is currently no evidence of a negative effect of the drug on the fetus. However, during pregnancy (especially in the first trimester), the drug should be prescribed with caution.

Safety of the drug during lactation has not been established. However, cases of unwanted effects in newborns have not been reported.

Composition

1 suppository contains:

Active substances: hyoscine butyl bromide - 10 mg.

Excipients: purified water - 10 mg, solid fat W45 - 1610 mg.

Dosage and administration

Rectally (suppositories), unless otherwise prescribed, for adults and children over 6 years of age - 1-2 supp. 3 times a day.

Suppositories should be removed from the membrane and inserted into the rectum with the pointed end forward.

Duration of use is determined by the doctor.

Side effects

Side effect associated with the anticholinergic action of the drug: dry mouth, dry skin, tachycardia, drowsiness, paresis of accommodation, difficulty urinating (usually mild and goes away on its own).

Allergic reactions: skin rash.

In rare cases: difficulty breathing

Drug Interaction

Buscopan can enhance the anticholinergic action of tricyclic and tetracyclic antidepressants, antihistamines, quinidine, amantadine, disopyramide, anticholinergic drugs (e.g.

Concurrent administration of Buskopan® and dopamine antagonists (eg, metoclopramide) leads to a weakening of the gastrointestinal tract of both drugs.

Buskopan can increase tachycardia caused by beta-adrenomimetics.

Overdose

Symptoms: urinary retention, dry mouth, redness of the skin, tachycardia, inhibition of gastrointestinal motility, transient visual impairment.

Treatment: gastric lavage with activated carbon and then with 15% magnesium sulfate (with overdose of tablets). Symptoms of overdose are stopped by cholinomimetics.

Patients with glaucoma are topically prescribed pilocarpine in the form of eye drops.

If necessary, cholinomimetics are systemically administered, for example neostigmine 0.5–2, 5 mg / m or in / in.

Cardiovascular complications are treated according to the usual therapeutic rules.

Intubation, IVL is indicated in paralysis of respiratory muscles. In case of urinary retention catheterize the bladder.

Supportive therapy is performed.

Storage conditions

Store in a dry place inaccessible to children, at a temperature not exceeding 25 ° C.

Expiration

5 years.

active ingredient

hyoscine butyl bromide

Dispensing conditions from pharmacies

Over-the-counter

dosage form

dosage form

rectal suppositories

Institut de Angeli Srl, Austria



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