Brownodin B. Brown brown ointment 20% 10 d1414 B. Brown solution of 7.5% spray 250 ml 20 pcs (Povidone-Iodine)

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Pharmacological action of

Pharmacotherapeutic group: Antiseptic agent

ATX:

D.08.AG02 Povidone-iodine

Pharmacodynamics: Antiseptic agent, which is a complex of iodine and povidone, effective at a pH of 2 to 7. Bactericidal action which is released from the povidone-iodine complex. Compared with alcohol-containing solutions of iodine, an aqueous solution of povidone-iodine has a significantly less irritating effect.

Free iodine as a strong oxidizing agent reacts at the molecular level with insoluble fatty acids and practically non-oxidizing SH- and OH-groups of amino acids in enzymes and the main structural components of bacteria, both gram-positive and gram-negative, mycobacteria, fungi, especially Candida genus , various viruses and some protozoa. However, for the complete inactivation of some viruses and bacterial spores, a sufficiently long period of exposure to the drug is necessary.

There are no known cases of the development of resistance in microorganisms with prolonged use of povidone iodine.

Pharmacokinetics: After the use of povidone-iodine, some absorption of iodine is possible, which must be taken into account depending on the place, amount and duration of the drug. If small amounts of the drug are applied to intact skin, then iodine absorption is negligible. An increase in absorption may result from prolonged use of drugs containing povidone-iodine on mucous membranes, extensive wounds and burns, and especially after rinsing cavities. As a result of this, a temporary increase in iodine in the blood is observed. In people with a healthy thyroid gland, a higher iodine content does not entail clinically significant changes in the state of the thyroid gland. In normal iodine metabolism, excess iodine is removed through the kidneys. Buy Brownodin B. Brown brown ointment 20% 10 d1414 B. Brown solution of 7.5% spray 250 ml 20 pcs (Povidone-Iodine) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Pharmacological action of

Pharmacotherapeutic group: Antiseptic agent

ATX:

D.08.AG02 Povidone-iodine

Pharmacodynamics: Antiseptic agent, which is a complex of iodine and povidone, effective at a pH of 2 to 7. Bactericidal action which is released from the povidone-iodine complex. Compared with alcohol-containing solutions of iodine, an aqueous solution of povidone-iodine has a significantly less irritating effect.

Free iodine as a strong oxidizing agent reacts at the molecular level with insoluble fatty acids and practically non-oxidizing SH- and OH-groups of amino acids in enzymes and the main structural components of bacteria, both gram-positive and gram-negative, mycobacteria, fungi, especially Candida genus , various viruses and some protozoa. However, for the complete inactivation of some viruses and bacterial spores, a sufficiently long period of exposure to the drug is necessary.

There are no known cases of the development of resistance in microorganisms with prolonged use of povidone iodine.

Pharmacokinetics: After the use of povidone-iodine, some absorption of iodine is possible, which must be taken into account depending on the place, amount and duration of the drug. If small amounts of the drug are applied to intact skin, then iodine absorption is negligible. An increase in absorption may result from prolonged use of drugs containing povidone-iodine on mucous membranes, extensive wounds and burns, and especially after rinsing cavities. As a result of this, a temporary increase in iodine in the blood is observed. In people with a healthy thyroid gland, a higher iodine content does not entail clinically significant changes in the state of the thyroid gland. In normal iodine metabolism, excess iodine is removed through the kidneys.

Indications

Post-traumatic and postoperative wounds of various locations, burns, trophic ulcers, pressure sores, diabetic foot.

Damage to the skin of various origins, maceration, abrasion, bruises. Infections of the skin of various etiologies, including infectious dermatitis and eczema. Treatment of mucous membranes and skin of the patient before and after surgery, biopsy, puncture, including the skin around the drainage, catheters and probes.

Hygienic treatment of the hands of medical personnel, processing of the hands of surgeons.

Infections of the oral mucosa and nasopharynx.

Infections of the mucous membrane of the birth canal in women. Conducting small gynecological operations (artificial termination of pregnancy, the introduction of an intrauterine device, coagulation of erosion and polyp).

Contraindications

Hypersensitivity to the drug.

Impaired thyroid function (thyrotoxicosis).

Adenoma of the thyroid gland.

Herpetiform dermatitis of Dühring.

Concomitant use of radioactive iodine.

Premature infants and children up to 6 months of age.

Precautions: Chronic renal failure.

Use during pregnancy and lactation

The drug is not recommended for use from the third month of pregnancy and during breastfeeding.

It is possible to use the solution in pregnant women up to the ninth week of pregnancy, when the expected benefit of treatment with the drug exceeds the possible risk of complications.

Composition of

100 g of the preparation contain:

active substance: diclofenac sodium 1,000 g

excipients: diisopropyl adipate 5,000 g hyprolose 2,000 g lactic acid 90% 0,044 g sodium disulfite 0,050 g isopropaiol 40,000 g purified water 51,968f rp 5190629 p5 1009 fpf9 pfard g of the solution contain:

active ingredient: povidone iodine (with 10% active iodine content) 7.5 g

excipients: sodium dihydrogen phosphate dihydrate, lauromacrogol-400, sodium iodate, sodium hydroxide, purified water up to 100 g

Dosage and administration

It is used to treat infected wounds of any etiology, preoperative treatment of the skin and mucous membranes, including the eye mucosa.

Used in the form of a 7.5% solution or in diluted form (1: 2–1: 20)

Does not cause irritation of the wound surface and mucous membranes

Used in preoperative preparation of patients: washing the body and limbs

The solution becomes more active when diluted

Side effects

Possible hypersensitivity reactions to the drug: delayed-type allergic reactions (itching, redness, blisters) or immediate allergic reactions (anaphylactoid reactions).

Long-term use of the drug (more than 7-10 days) and application to large skin surfaces, extensive wounds due to absorption can cause iodism (metallic taste in the mouth, excessive salivation and lacrimation, swelling of the mucous membranes) and systemic reactions (metabolic acidosis, hyponatremia, impaired renal and thyroid function), when they appear, stop using the drug and consult a doctor.

Overdose of

After extremely intense absorption of iodine over an extended period, symptoms of hyperthyroidism, such as tachycardia, agitation, trembling, and headache, may be noted. Mild forms of hyperthyroidism sometimes do not require intervention, and severe forms may require thyrostatic therapy.

Storage conditions

Store at a temperature of 2 to 25 ° C in a dark place.

Keep out of the reach of children.

Expiration

3 years.

Active substance

povidone-iodine

Dosage form

topical solution



Brownodin B. Brown brown ointment 20% 10 d1414 B. Brown solution of 7.5% spray 250 ml 20 pcs (Povidone-Iodine) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Brownodin B. Brown brown ointment 20% 10 d1414 B. Brown solution of 7.5% spray 250 ml 20 pcs - Sale. PayPal accept. Free shipping florida. Fast international shipping.

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