Bronchobos syrup 250 mg / 5 ml fl. 200ml

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SKU
FL10208913
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Category

Thinning phlegm

,

Expectorants

Scope of the drug

Respiratory system

Release form

Syrup

Manufacturer country

Bosnia and Herzegovina

Package quantity, pcs

one

Description

Release form, composition and packaging

?

Syrup 5% in the form of a transparent slightly viscous liquid from pink to red, with a raspberry scent.

5 ml (1 measuring spoon)

carbocisteine ��250 mg

glycerol - 135 mg, ethanol 96% - 125 mg, sodium hydroxide - 61 mg, sodium carmellose - 20 mg, citric acid monohydrate - 10 mg, methyl parahydroxybenzoate - 9 mg, sodium saccharinate - 5 mg, propyl parahydroxybenzoate - 1 mg, raspberry flavor - 0.7 mg, azorubin CI14720 (E122) - 0.05 mg, purified water - up to 5 ml.

200 ml - dark glass bottles (1) complete with a measuring spoon with marked labels 2.5 ml and 5 ml - cardboard packs.

pharmachologic effect

Mucolytic and expectorant drug.

Mucolytic and expectorant action is due to the activation of sialic transferase - an enzyme of the goblet cells of the bronchial mucosa.

Normalizes the quantitative ratio of acidic and neutral sialomucins of bronchial secretions.

Reduces the viscosity of bronchial secretions and discharge from the paranasal sinuses, facilitates the discharge of sputum and mucus, and reduces coughing.

Promotes regeneration of the mucous membrane, normalizes its structure, activates the activity of the ciliated epithelium.

Restores the secretion of IgA immunoglobulin (specific protection) and the number of sulfhydryl groups of mucus components (non-specific protection), improves mucociliary clearance.

Pharmacokinetics

Absorption and distribution Carbocisteine ��is rapidly absorbed after oral administration.

Bioavailability is low (less than 10% of the dose taken).

Cmax in blood serum and in the mucous membrane of the respiratory tract is achieved 2-3 hours after ingestion of the drug and remains in the mucous membrane for 8 hours. Metabolism and excretion Metabolized in the liver (has the effect of first passage" through the liver).

It is excreted mainly by the kidneys, partly unchanged, partly in the form of metabolites.

T1 / 2 - about 2 hours

Indications for use

- acute and chronic bronchopulmonary diseases, accompanied by the formation of viscous, difficult to separate sputum (tracheitis, bronchitis, tracheobronchitis, bronchial asthma, bronchiectasis)

- inflammatory diseases of the middle ear (otitis media)

- inflammatory diseases of the nose and its paranasal sinuses (rhinitis, sinusitis)

- preparation for bronchoscopy and / or bronchography.

Contraindications for use

- hypersensitivity to carbocisteine ��and other components of the drug

- peptic ulcer of the stomach and duodenum in the acute phase

- chronic glomerulonephritis in the acute phase

- cystitis

- liver disease (for taking syrup)

- alcoholism (for taking syrup)

- epilepsy (for taking syrup)

- trauma or diseases of the brain (for taking syrup)

- pregnancy

- lactation (breastfeeding)

- children's age up to 3 years (for taking syrup 2.5%)

- children under 15 years of age (for taking capsules and syrup 5%).

With caution: with chronic glomerulonephritis (in history), gastric ulcer and duodenal ulcer (in history), in II-III trimesters of pregnancy and during breastfeeding.

Dosage regimen

The drug is administered orally.

Capsules Adults and adolescents over 15 years of age: 750 mg (2 capsules) 3 times / day.

After reaching the therapeutic effect, the daily dose is reduced to 1.5 g: 750 mg (2 capsules) 2 times / day.

Treatment should not be continued for more than 8-10 days without consulting a doctor.

Syrup To dose the syrup, use a 5 ml measuring spoon, graduated to 2.5 ml.

1 scoop of 5% syrup (5 ml) = 250 mg carbocysteine

1 scoop of syrup 2.5% (5 ml) = 125 mg carbocisteine ��Adults: 15 ml (3 scoops) of 5% syrup 3 times / day.

Children aged 3-6 years: 5 ml (1 scoop) 2.5% syrup 2-4 times / day.

Children over the age of 6: 5-10 ml (1-2 scoops) 2.5% syrup

Name ENG

BRONCHOBOS

Clinical and pharmacological group

Mucolytic drug

ATX code

Carbocisteine

Dosage

250mg / 5ml x 200ml

Structure

5 ml of syrup contains: Active ingredient: carbocisteine ��250 mg

Excipients: glycerol 135 mg

ethanol 96% 125 mg

sodium hydroxide 61 mg

carmellose sodium 20 mg

citric acid monohydrate 10 mg

methyl parahydroxybenzoate 9 mg

sodium saccharinate 5 mg

propyl parahydroxybenzoate 1 mg

raspberry flavor 0.7 mg

azorubin CI 14720 (E122) 0.05 mg

purified water up to 5 ml.

Indications

acute and chronic bronchopulmonary diseases, accompanied by a violation of the formation and excretion of mucus (tracheitis, bronchitis, tracheobronchitis, bronchial asthma, bronchiectasis)

inflammatory diseases of the middle ear and paranasal sinuses (rhinitis, otitis media, sinusitis)

preparation of the patient for bronchoscopy or bronchography.

Contraindications

hypersensitivity to the drug or its auxiliary components

peptic ulcer of the stomach and duodenum in the acute stage

chronic glomerulonephritis (in the acute phase)

cystitis

children under 15 years old

liver disease

alcoholism

epilepsy

brain injury or disease

pregnancy

lactation.,

With care: gastric ulcer and duodenal ulcer (in history).

Storage conditions and periods

At a temperature not higher than 30 degrees.

(do not freeze).

Expiration date: 3 years

INN / Active ingredient

carbocisteine

Specifications

Category

Thinning phlegm

,

Expectorants

Scope of the drug

Respiratory system

Release form

Syrup

Manufacturer country

Bosnia and Herzegovina

Package quantity, pcs

one

Scope of application

Virology

Minimum age from

18 years

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Shelf life after opening

1 month

Brand name

Bosnalek +

Components

measuring spoon

The amount of the dosage form in the primary package

200 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Expectorant mucolytic agent

Anatomical and therapeutic characteristics

R05CB03 Carbocisteine

Dosage form

Syrup

Expiration date in days

1095

Dosage (volume) of the substance in the preparation

carbocisteine ��250 mg

Package weight, g

425

Mode of application

:

Inside. < br> For the dosage of the syrup, a 5 ml measuring spoon is used, graduated to 2.5 ml.

1 scoop of syrup 5% (5 ml) = 250 mg of carbocisteine ��1 scoop of syrup 2.5% (5 ml) = 125 mg of carbocysteine. < br> Adults - 15 ml (3 scoops) of 5% syrup 3 times day.

Information on technical characteristics, delivery set, country of manufacture "

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