Bondronate tablets 50 mg, 28 pcs. (Ybandronovaya acid)

Release form

film-coated tablets.

Packing

28 pcs.

Pharmacological action

Bone resorption inhibitor, bisphosphonate. It reduces bone resorption of Ca2 +, stimulates osteogenesis, and regulates calcium-phosphorus metabolism. Bondronate increases bone mass, does not inhibit bone mineralization. One infusion of 2 mg of the drug normalizes the content of Ca2 + in the blood serum, the effect persists for several weeks. In women with postmenopausal osteoporosis, a 4-fold intravenous injection every 3 months is accompanied by an increase in bone mass in the spine by 6.25%, and in the proximal femur by 2.96%.

Contraindications

Hypersensitivity, serum creatinine more than 5 mg% (442 Ојmol / L), aspirin asthma, childhood, pregnancy, lactation.

Special instructions

Monitor renal function, serum Ca2 + and Mg2 +.

Composition

1 tablet contains 50 mg ibandronic acid.

Dosage and administration

Tablets are taken orally at least 30 minutes before the first meal of the day, liquid or other than pure water, or other drugs and dietary supplements. The tablets should be swallowed whole, washed down with a glass (180–240 ml) of clean water in the “sitting” or “standing” position and not go to bed for 60 minutes after taking Bondronate. Tablets should not be chewed or resorbed due to the possible formation of oropharyngeal ulcerations. Do not use mineral water with a high calcium content.

Side effects

Hyperthermia, flu-like syndrome (fever, chills, ossalgia, myalgia), decreased excretion of Ca2 + by the kidneys, hypocalcemia, hypophosphatemia, nausea, vomiting, bronchospasm (in patients with aspirin bronchus). Allergic reactions. Local reactions: pain and burning at the injection site, phlebitis.

Drug interaction

Aminoglycosides increase the risk of hypocalcemia.

Overdose

Symptoms: hypocalcemia (convulsions, Trusso, Hvostek, Weiss, Schlesinger symptoms, prolonged QT interval with isoelectric ST interval), impaired renal and hepatic function.

Treatment: Ca2 + preparations, hemodialysis (with a critical change in the plasma level of creatinine and electrolytes).

Storage Conditions

At a temperature not exceeding 30 ° C.

Dosage form

tablet

Appointment

Adult prescription

Indications

Fractures, Climax, Osteoporosis

Possible product names

BONDRONFL18 NON-6FLF 18 DFrew 6 NF1 6FL18 DFrew 18 Possible product names

BONDRONATE TAB 50 MG No. 28

Bondronate tablets 50 mg, 28 pcs.



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