Bidop tablets 10 mg, 28 pcs. (bisoprolol)

Release form

Tablets

Packing

28 pcs.

Pharmacological action

Bidop is a selective beta1-blocker without internal sympathomimetic activity, does not have a membrane-stabilizing effect. Bidop reduces plasma renin activity, reduces myocardial oxygen demand, reduces heart rate (at rest and under load).

It has hypotensive, antiarrhythmic and antianginal effects.

Blocking 1-adrenergic receptors of the heart in low doses, it reduces the cAMP production from ATP stimulated by catecholamines, reduces the intracellular current of calcium ions, has a negative chrono-, dromo-, batmo- and inotropic effect, inhibits conduction and excitability, and reduces myocardial contractility.

With increasing doses has a beta2-blocking effect.

Indications

Arterial hypertension prevention of angina attacks.

Use during pregnancy and lactation

Use Bidop during pregnancy and during breastfeeding is possible if the benefit to the mother outweighs the risk of side effects in the fetus and the baby.

Special instructions

Monitoring patients receiving Bidop should include a measurement of heart rate and blood pressure (at the beginning, lay down- daily, then 1 time in 3-4 months), ECG, determination of blood glucose in patients with diabetes mellitus (1 time in 4-5 months).

In elderly patients, it is recommended to monitor renal function (1 time in 4-5 months).

Composition of

1 tablet contains bisoprolol hemifumarate 10 mg

Dosage and administration

Inside, in the morning, on an empty stomach, without chewing, 2.5–5 mg bidop once.

If necessary, increase the dose to 10 mg once a day.

The maximum daily dose is 20 mg per day.

Drug Interactions

Allergens used for immunotherapy or allergen extracts for skin tests increase the risk of severe systemic allergic reactions or anaphylaxis in patients receiving bisoprolol.

Iodine-containing radiopaque drugs for iv administration increase the risk of anaphylactic reactions.

Phenytoin with iv administration, drugs for inhalation general anesthesia (hydrocarbon derivatives) increase the severity of cardiodepressive action and the likelihood of lowering blood pressure.

Changes the effectiveness of insulin and oral hypoglycemic drugs, masks the symptoms of developing hypoglycemia (tachycardia, increased blood pressure).

Reduces the clearance of lidocaine and xanthines (except theophylline) and increases their plasma concentration, especially in patients with initially increased clearance of theophylline under the influence of smoking.

Antihypertensive effect is weakened by NSAIDs (sodium ion retention and prostaglandin synthesis blockade by the kidneys), corticosteroids and estrogens (sodium ion retention).

Cardiac glycosides, methyldopa, reserpine and guanfacine, slow calcium channel blockers (verapamil, diltiazem), amiodarone, and other antiarrhythmic drugs increase the risk of developing or worsening bradycardia, AV block, heart failure and heart failure.

Overdose

Symptoms: arrhythmia, ventricular extrasystole, severe bradycardia, AV block, marked decrease in blood pressure, chronic heart failure, cyanosis of fingernails or palms of the fingers, shortness of breath, bronchospasm, dizziness, fainting, convulsions, hypoglycemia.

Treatment: gastric lavage and the administration of adsorbing drugs symptomatic therapy: with developed AV-blockade - I / O 1-2 mg of atropine, epinephrine or setting up a temporary pacemaker with ventricular extrasystole - lidocaine (IA class drugs are not used) with a decrease in blood pressure - patient should be in the Trendelenburg position if there are no signs of pulmonary edema, - iv plasma-replacing solutions, with inefficiency - the introduction of epinephrine, dopamine, dobutamine (to maintain chronotropic and inotropic effects and eliminate a pronounced decrease in blood pressure) in heart failure - cardiac glycosides, diuretics, glucagon for seizures - iv diazepam for bronchospasm - beta2-adrenostimulators inhaled.

Storage conditions

Store in a dry, dark place out of the reach of children, at temperatures not exceeding 20 ° C.

Deystvuyuschee substances

bisoprolol

Prescription terms from

pharmacies Prescription

Dosage form

tablet

Appointment

for Adults on purpose doctor

Indications

heart failure, arrhythmia, hypertension

Possible product names

BIDOP 0.01 N28 TABLE

BIDOP 0.01 N28 TABLE P / O

Bidop 10mg Tab. X28 (R)

bidop tablet 10mg N28

bidop tablet 10mg x 28

Gedeon Richter-Rus Vengriya



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