Betamethasone, Gentamicin (Betamethasone, Gentamicin)

Release form

Ointment.



tube 30 g

Pharmacological action

Akriderm GENTA is a combined preparation for external use with anti-inflammatory, anti-allergic and antibacterial effects.

Betamethasone dipropionate - a glucocorticosteroid, has anti-inflammatory, anti-allergic, anti-exudative, decongestant and antipruritic effect. It inhibits the accumulation of white blood cells, the release of lysosomal enzymes and pro-inflammatory mediators in the focus of inflammation, inhibits phagocytosis, reduces vascular tissue permeability, and prevents the formation of inflammatory edema.

Gentamicin is a broad-spectrum antibiotic from the aminoglycoside group. It has a bactericidal effect against pathogens of primary and secondary bacterial infections of the skin. Active against gram-negative bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae gram-positive bacteria: Streptococcus spp. (sensitive strains of beta and alpha hemolytic streptococcus group A), Staphytococcus spp. (coagulase-positive, coagulase-negative and some penicillinase producing strains). Inactive against anaerobes, fungi and viruses.

Contraindications

- hypersensitivity to the components of the drug,

- skin tuberculosis,

- viral infections of the skin,

- vaccinations,

- perioral dermatitis,

- rosacea (rosacea).

Special instructions

The drug is not used in ophthalmology. Avoid contact with eyes, damaged skin, and open wound sites.

In order to increase the effectiveness of therapy, the use of occlusive dressings is possible. It should be borne in mind that this increases the transdermal absorption of betamethasone and gentamicin, which leads to an increased risk of developing systemic side effects.

If a stable bacterial or fungal microflora appears, discontinue use of the drug and prescribe appropriate therapy. cross resistance with aminoglycoside antibiotics is possible.

Composition

1 gram contains:

0.64 mg betamethasone dipropionate (equivalent to 0.5 mg betamethasone)

gentamicin sulfate - 1 mg.

Dosage and administration

The drug Akriderm GENTA is applied in a thin layer on the inflamed surface twice a day, gently rubbing. In milder cases, a single use is sufficient. The duration of treatment is determined individually and depends on the nosological form and severity of the disease and is usually 1-2 (rarely 4 weeks). If you need a long course of therapy, it is recommended to use the drug less often, for example, every other day.

In the treatment of chronic diseases under the constant supervision of a physician, treatment should be continued for some time after the disappearance of all symptoms in order to avoid relapse of the disease.

The use of the drug in children under 12 years of age is carried out under the supervision of a physician.

Side effects

- burning,

- dry skin,

- folliculitis,

- hypertrichosis,

- hypopigmentation, allergic contact dermatitis,

- atrophy of the skin,

- stria,

- stria.

Drug Interactions

Drug interactions with other drugs have not been identified.

Overdose

An acute overdose is unlikely, however, with excessive or prolonged use of the drug, a chronic overdose is possible, accompanied by signs of hypercorticism: hyperglycemia, glucosuria, reversible inhibition of adrenal cortex, manifestation of Cushing's syndrome.

treatment.

Appropriate symptomatic treatment is indicated.

In case of chronic toxic effects, gradual discontinuation of the drug is recommended.

Storage conditions

At a temperature of 15 to 25 ° C out of the reach of children.

Expiration

2 years.

active substance

Betamethasone, Gentamicin

lekarstvennaja form

ointment

Prescription

For children over 1 year old, For adults, Pregnant as prescribed by doctor, Prescribed children Racha

Akrikhin CPC JSC, Russia



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