betamethasone, fusidic acid (betamethasone, fusidic acid)

Release form

Cream.

Packaging

In an aluminum tube 15 g of cream. In a cardboard bundle 1 tube.

Pharmacological action

Fucicort - a combined preparation for external use, combines the anti-inflammatory and antipruritic effect of betamethasone with the antimicrobial effect of fusidic acid.

Highly active against: Staphylococcus spp, especially Staphylococcus aureus and Staphylococcus epidermidis (including methicillin-resistant strains), Streptococcus spp, Neisseria spp, Clostridium spp, Nocardia asteroides, Enterococcus spp, Bacteroides spp, Mycobacterium tuberculosis, Mycobacterium leprae, Corynebacterium minutissimum.

The antibacterial activity of fusidic acid does not decrease in the presence of betamethasone.

Indications

Dermatitis with or suspected bacterial infection:

- Atopic dermatitis.

- Seborrheic dermatitis.

- Simple contact dermatitis.

- Allergic dermatitis.

- Eczema.

- Chronic lichen.

- Red discoid lupus.

Contraindications

- Tuberculosis of the skin.

- Cutaneous manifestations of syphilis.

- Chicken pox.

- Viral and fungal infections of the skin.

- Dermal post-vaccination reactions.

- Open wounds.

- Trophic ulcers.

- Rosacea.

- Acne vulgaris.

- Hypersensitivity to the drug.

Use during pregnancy and lactation

Since clinical studies of the drug during pregnancy and lactation have not been conducted, the drug should not be used during pregnancy at high doses and for a long time during lactation (breastfeeding), the drug should not be applied to milk glands. In experimental studies, it was found that Fucicort does not have embryotoxic and teratogenic properties. With the external use of Fucicort, the secretion of both fusidic acid and betamethasone with breast milk is unlikely due to the low systemic absorption.

Composition

1 g of cream for external use contains: fusidic acid micronized (in terms of anhydrous acid) 20 mg, betamethasone valerate (in terms of betamethasone) 1 mg.

Excipients: macrogol cetostearyl ether, cetostearyl alcohol, chlorcresol, sodium dihydrogen phosphate dihydrate, liquid paraffin, white soft paraffin, sodium hydroxide, purified water.

Dosage and administration

Fucicort cream is applied to the affected area with a thin layer 2 times / day. The course of treatment is 2 weeks.

Side effects

Dermatological reactions: 1-2% (as with other GCS) - itching, burning, redness, tingling, dry skin, as well as irritation, rash rarely - acne-like changes, hypopigmentation, folliculitis, striae, skin atrophy , hypertrichosis, allergic contact dermatitis.

Side effects with external use are rare and are reversible.

In case of development of hypersensitivity reactions or side effects, therapy should be discontinued.

overdose

Exceeding the recommended doses, prolonged use of topical ACS on a vast surface of the skin can lead to suppression of the function of the hypothalamic-pituitary-adrenal system and the development of symptoms of hypercorticism.

Treatment: gradual withdrawal of the drug is recommended, symptomatic therapy, if necessary, corrects the electrolyte balance.

Storage Conditions

The product should be stored at a temperature not exceeding 25 ° C.

Shelf life

3 years.

Deystvuyushtee substance

Betamethasone, Fuzidovaya Chisloth

dosage form

cream

LEO Leboratoris Limited, Ireland



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