Aspirin express for headache treatment

Release form, composition and packaging

The tablets are white, round, slightly biconvex, beveled to the edge, with an imprint in the form of a trademark (Bayer" cross) on one side and "ASPIRIN 0.5" on the other.

1 tab.

acetylsalicylic acid 500 mg

microcrystalline cellulose, corn starch.

10 pieces.

- blisters (1) - cardboard packs.

10 pieces.

- blisters (2) - cardboard packs.

10 pieces.

- blisters (10) - cardboard packs.

pharmachologic effect

Acetylsalicylic acid (ASA) belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDs) and has analgesic, antipyretic and anti-inflammatory effects due to inhibition of cyclooxygenase enzymes involved in the synthesis of protaglandins.

ASA in the dose range of 0.3 to 1.0 g is used to reduce fever in diseases such as colds and flu and to relieve joint and muscle pain.

ASA inhibits platelet aggregation by blocking the synthesis of thromboxane A2 in platelets.

Indications for use

- for symptomatic relief of headache, toothache, sore throat, pain during menstruation, pain in muscles and joints, back pain

- elevated body temperature with colds and other infectious and inflammatory diseases (in adults and children over 15 years old).

Contraindications for use

- erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase)

- hemorrhagic diathesis

- bronchial asthma induced by the intake of salicylates and other NSAIDs

- combined use with methotrexate at a dose of 15 mg per week or more

- I and III trimesters of pregnancy and the period of breastfeeding

- hypersensitivity to ASA, other NSAIDs or any excipients of the drug.

The drug is not prescribed for children under 15 years of age with acute respiratory diseases caused by viral infections, due to the risk of developing Reye's syndrome (encephalopathy and acute fatty liver disease with acute development of liver failure).

With caution - with concomitant treatment with anticoagulants, gout, hyperuricemia, gastric ulcer and / or duodenal ulcer (in history), including chronic or recurrent peptic ulcer disease, as well as gastrointestinal bleeding

bronchial asthma, nasal polyposis, chronic broncho-pulmonary diseases

in case of impaired renal and / or liver function

in the II trimester of pregnancy.

Dosage regimen

The drug is intended for adults and children over 15 years of age:

With pain syndrome of mild and moderate intensity and febrile conditions, a single dose is 0.5-1 g, the maximum single dose is 1 g. The intervals between doses of the drug should be at least 4 hours. The maximum daily dose should not exceed 3 g (6 tab.).

Take orally after meals with plenty of liquid.

The duration of treatment (without consulting a doctor) should not exceed 7 days when prescribed as an anesthetic and more than 3 days as an antipyretic agent.

Overdose

Symptoms

Moderate overdose is characterized by nausea, vomiting, tinnitus, hearing impairment, headache, dizziness, and confusion.

These symptoms disappear when the dose of the drug is reduced.

Overdose of severe severity is characterized by fever, hyperventilation, ketosis, respiratory alkalosis, metabolic acidosis, coma, cardiogenic shock, respiratory failure, severe hypoglycemia.

Treatment: hospitalization, lavage, intake of activated carbon, control of acid-base balance, alkaline diuresis to obtain urine pH values ��in the range of 7.5-8.0 (forced alkaline diuresis is considered achieved when the concentration of salicylate in the blood is more than 500 mg / l (3.6 mmol / l) in adults and 300 mg / l (2.2 mmol / l) in children, hemodialysis, replacement of fluid loss, symptomatic therapy.

Name ENG

ASPIRIN

Clinical and pharmacological group

NSAIDs.

Antiplatelet agent

ATX code

Acetylsalicylic acid

Dosage

500mg

Structure

1 tablet for the preparation of an effervescent drink contains: Active ingredients Acetylsalicylic acid - 500 mg.

Excipients Microcrystalline cellulose, corn starch.

Indications

Symptomatic treatment:

Headache.

Toothache.

Sore throat.

Muscle and joint pain.

Pain during menstruation. Pain in the back.

Mild arthritis pain.

Elevated body temperature with colds and other infectious and inflammatory diseases (in adults and children over 15 years old).

INN / Active ingredient

Acetylsalicylic acid

Contraindications

Hypersensitivity to acetylsalicylic acid and other NSAIDs.

Erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase).

Gastrointestinal bleeding.

Asthma caused by the intake of salicylates or other NSAIDs, in combination with nasal polyps.

Combined use of methotrexate at a dose of 15 mg per week or more.

Severe liver or kidney dysfunction.

Hemorrhagic diathesis.

Hemophilia, thrombocytopenia.

Deficiency of glucose-6-phosphate dehydrogenase.

Pregnancy (I and III trimester).

Breastfeeding period.

Children's age (up to 15 years old).

With caution in the following cases:

With concomitant anticoagulant therapy.

Gout.

Peptic ulcer of the stomach and / or duodenum (in history).

Erosive gastritis.

Tendency to gastrointestinal bleeding.

Hypoprothrombinemia.

Hypovitaminosis K.

Anemia.

Conditions that predispose to fluid retention in the body (including dysfunction of the heart, arterial hypertension).

Thyrotoxicosis.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

Specifications

Category

Pain and fever

,

Pain relievers

,

Migraine

Scope of the drug

General

Release form

Tablet

Manufacturer country

Germany

Package quantity, pcs

12

Minimum age from

15 years

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Aspirin

The amount of the dosage form in the primary package

2 pcs.

Primary packaging type

Cell-free contoured packaging (strip)

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

NSAIDs

Anatomical and therapeutic characteristics

N02BA01 Acetylsalicylic acid

Dosage form

Effervescent tablets

Dosage (volume) of the substance in the preparation

500 mg

Expiration date in days

1095

The target audience

Children

Package weight, g

thirty

Mode of application

:

Inside, after eating, after dissolving the tablet in a glass of water.

A single dose is 1�2 effervescent tablets.

The maximum single dose is 2 effervescent tablets.

The maximum daily dose should not exceed 6 tablets.

The intervals between doses of the drug should be at least 4 hours. The duration of treatment without consulting a doctor should not exceed 5 days - when prescribed as an anesthetic and 3 days - as an antipyretic agent.

Information on technical characteristics, delivery set, country of manufacture "