Aspirin cardio tablets 100 mg, 28 pcs. (Atsetylsalytsylovaya acid)
Special Price
$22.77
Regular Price
$23.00
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florida471199
Latin name
Aspirin Cardio Buy Aspirin cardio tablets 100 mg, 28 pcs. (Atsetylsalytsylovaya acid) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Aspirin Cardio Buy Aspirin cardio tablets 100 mg, 28 pcs. (Atsetylsalytsylovaya acid) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Latin name
Aspirin Cardio
Release form
Enteric coated tablets.
Packing
28 pcs.
Pharmacological action
Aspirin cardio - non-steroidal anti-inflammatory drug (NSAIDs), non-narcotic analgesic, antiplatelet agent. It has an antipyretic, analgesic and anti-inflammatory effect, and also reduces platelet aggregation.
The main mechanism of action of acetylsalicylic acid is the irreversible inactivation of the cyclooxygenase enzyme, as a result of which the synthesis of prostaglandins, prostacyclins and thromboxane is disrupted.
Due to a decrease in prostaglandin production, the pyrogenic effect of prostaglandins on thermoregulation centers is reduced. In addition, the sensitizing effect of prostaglandins on sensitive nerve endings is reduced (which leads to a decrease in their sensitivity to pain mediators).
Irreversible thromboxane A2 synthesis in platelets causes the antiplatelet effect of acetylsalicylic acid.
However, please note that acetylsalicylic acid also blocks cyclooxygenase of endothelial cells in which prostacyclin with antiplatelet activity is synthesized. However, endothelial cell cyclooxygenase is less sensitive to the action of acetylsalicylic acid and, unlike the platelet enzyme, is blocked reversibly.
The use of film-coated tablets resistant to the action of gastric juice reduces the incidence of side effects from the stomach.
Sodium bicarbonate, which is part of effervescent tablets, neutralizes free hydrochloric acid in the stomach (to pH 6.0-7.0), which reduces the irritating effect of acetylsalicylic acid on the gastrointestinal mucosa.
Indications
- prevention of acute myocardial infarction in the presence of risk factors (including diabetes mellitus, hyperlipidemia, hypertension, smoking, advanced age) and recurrent myocardial infarction
- unstable angina pectoris
- prevention of stroke (including in patients with transient cerebrovascular accident)
- prevention of transient cerebrovascular accident
- prevention of thromboembolism after surgery and including coronary artery bypass grafting, carotid endarterectomy, arteriovenous bypass grafting, carotid artery angioplasty)
- prevention of deep vein thrombosis and pulmonary embolism and e branches (including at prolonged immobilization resulting from extensive surgery).
Contraindications
- acute and recurrent erosive and ulcerative diseases of the gastrointestinal tract
- hemorrhagic diathesis
- bronchial asthma, induced by salicylates and NSAIDs
- combined use with methotrexate at a dose of 15 mg per week
- renal failure
- hepatic insufficiency
- severe heart failure in the stage of decompensation
- arterial hypertension
systole stenocardia - angina pectoris pregnancy trimesters
- lactation (breastfeeding)
- hypersensitivity to acetylsalicylic acid, other salicylates or any components of the drug.
The drug is not prescribed for children under the age of 15 years with acute respiratory infections caused by viral infections, because of the risk of Reye's syndrome (encephalopathy and acute fatty degeneration of the liver with acute development of liver failure).
With caution, the drug should be prescribed for gout, hyperuricemia in patients with a history of gastrointestinal ulcer (including gastric and duodenal ulcer) or gastrointestinal bleeding, impaired renal and hepatic function, bronchial asthma, chronic diseases respiratory organs, hay fever, polyposis of the nasal mucosa in case of allergic reactions to drugs (including NSAIDs), in the second trimester of pregnancy.
Use during pregnancy and lactation
The drug is contraindicated for use in the I and III trimesters of pregnancy. The use of salicylates in high doses in the first trimester is associated with an increased frequency of fetal developmental defects (split palate, heart defects). In the III trimester, the use of salicylates in high doses (more than 300 mg / day) causes inhibition of labor, premature closure of the ductus arteriosus in the fetus, increased bleeding in the mother and fetus, and administration immediately before birth can cause intracranial hemorrhages, especially in premature babies.
Prescribing in the second trimester of pregnancy is possible only after a careful assessment of the expected benefits to the mother and the potential risk to the fetus.
During lactation with prolonged use or when taking acetylsalicylic acid in high doses, breastfeeding should be discontinued. Accidental intake of salicylates during lactation does not require cessation of breastfeeding. Salicylates and their metabolites in small quantities are excreted in breast milk.
Composition
1 tablet contains 100 mg acetylsalicylic acid.
Dosage and administration of
Aspirin cardio is prescribed by mouth.
For prophylaxis in cases of suspected acute myocardial infarction, the recommended dose is 100-200 mg / day or 300 mg every other day. The first tablet is recommended to chew for faster absorption.
For the prevention of acute acute myocardial infarction in the presence of risk factors, the recommended dose is 100 mg / day or 300 mg every other day.
For the prevention of recurrent myocardial infarction, with unstable angina, for the prevention of stroke, transient cerebrovascular accident and thromboembolic complications after surgical procedures on the vessels, the drug is prescribed at a dose of 100-300 mg / day.
For the prevention of deep vein thrombosis and thromboembolism of the pulmonary artery and its branches, the recommended dose is 100-200 mg / day or 300 mg every other day.
Aspirin Cardio is intended for long-term use, the duration of therapy is set individually.
Aspirin Cardio tablets are taken before meals with plenty of fluids.
Side effects of
From the gastrointestinal tract: nausea, anorexia, pain in the epigastric region in some cases (especially with frequent and prolonged use of the drug) are possible - erosive and ulcerative lesions of the gastrointestinal tract, hidden blood loss from the gastrointestinal tract, signs of gastrointestinal bleeding (tarry stool )
From the hematopoietic system: very rarely - thrombocytopenia, anemia (due to hidden bleeding from the digestive tract).
Allergic reactions: rarely (especially in patients with bronchial asthma) - skin rash, bronchospasm.
Drug Interaction
When used together, Aspirin Cardio enhances the effects of methotrexate by reducing its renal clearance and displacing it from its association with blood plasma proteins.
With the simultaneous use of Aspirin Cardio, it enhances the action of heparin and indirect anticoagulants by disrupting platelet function and displacing indirect anticoagulants from blood plasma protein bonds.
Aspirin Cardio with combined use enhances the action of thrombolytic and antiplatelet drugs (including ticlopidine).
Aspirin Cardio by reducing renal clearance increases the concentration of digoxin in blood plasma and enhances its effects.
Aspirin Cardio enhances the effects of hypoglycemic drugs (insulin and sulfonylurea) due to the hypoglycemic effect of acetylsalicylic acid and the displacement of sulfonylurea derivatives from communication with blood plasma proteins.
When used together, Aspirin Cardio reduces the effect of uricosuric drugs (benzbromarone).
With the use of ACS, salicylate excretion is enhanced.
overdose
Symptoms: overdose of moderate severity - nausea, vomiting, tinnitus, hearing loss, dizziness, confusion in severe degree - fever, hyperventilation, ketoacoracid, hyperglycemia. Overdose is most likely in elderly patients.
Treatment: in case of overdose of moderate severity - reduction of the dose of the drug in severe - immediate hospitalization for emergency therapy - activated charcoal, gastric lavage, determination of acid-base balance, alkaline and forced alkaline diuresis, diuretic diarrhea, diuresis. When carrying out alkaline diuresis it is necessary to achieve pH values between 7.5-8. Forced alkaline diuresis should be performed at plasma salicylate concentrations greater than 500 mg / l (3.6 mmol / l) in adults and 300 mg / l (2.2 mmol / l) in children.
Storage conditions
The drug should be stored out of the reach of children at a temperature not exceeding 25 ° C.
Expiration
5 years.
Deystvuyuschee substances
Atsetylsalytsylovaya acid
pharmacy leave terms without a prescription
dosage form
dosage form
tablets
Aspirin cardio tablets 100 mg, 28 pcs. (Atsetylsalytsylovaya acid) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Aspirin cardio tablets 100 mg, 28 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.
Aspirin Cardio
Release form
Enteric coated tablets.
Packing
28 pcs.
Pharmacological action
Aspirin cardio - non-steroidal anti-inflammatory drug (NSAIDs), non-narcotic analgesic, antiplatelet agent. It has an antipyretic, analgesic and anti-inflammatory effect, and also reduces platelet aggregation.
The main mechanism of action of acetylsalicylic acid is the irreversible inactivation of the cyclooxygenase enzyme, as a result of which the synthesis of prostaglandins, prostacyclins and thromboxane is disrupted.
Due to a decrease in prostaglandin production, the pyrogenic effect of prostaglandins on thermoregulation centers is reduced. In addition, the sensitizing effect of prostaglandins on sensitive nerve endings is reduced (which leads to a decrease in their sensitivity to pain mediators).
Irreversible thromboxane A2 synthesis in platelets causes the antiplatelet effect of acetylsalicylic acid.
However, please note that acetylsalicylic acid also blocks cyclooxygenase of endothelial cells in which prostacyclin with antiplatelet activity is synthesized. However, endothelial cell cyclooxygenase is less sensitive to the action of acetylsalicylic acid and, unlike the platelet enzyme, is blocked reversibly.
The use of film-coated tablets resistant to the action of gastric juice reduces the incidence of side effects from the stomach.
Sodium bicarbonate, which is part of effervescent tablets, neutralizes free hydrochloric acid in the stomach (to pH 6.0-7.0), which reduces the irritating effect of acetylsalicylic acid on the gastrointestinal mucosa.
Indications
- prevention of acute myocardial infarction in the presence of risk factors (including diabetes mellitus, hyperlipidemia, hypertension, smoking, advanced age) and recurrent myocardial infarction
- unstable angina pectoris
- prevention of stroke (including in patients with transient cerebrovascular accident)
- prevention of transient cerebrovascular accident
- prevention of thromboembolism after surgery and including coronary artery bypass grafting, carotid endarterectomy, arteriovenous bypass grafting, carotid artery angioplasty)
- prevention of deep vein thrombosis and pulmonary embolism and e branches (including at prolonged immobilization resulting from extensive surgery).
Contraindications
- acute and recurrent erosive and ulcerative diseases of the gastrointestinal tract
- hemorrhagic diathesis
- bronchial asthma, induced by salicylates and NSAIDs
- combined use with methotrexate at a dose of 15 mg per week
- renal failure
- hepatic insufficiency
- severe heart failure in the stage of decompensation
- arterial hypertension
systole stenocardia - angina pectoris pregnancy trimesters
- lactation (breastfeeding)
- hypersensitivity to acetylsalicylic acid, other salicylates or any components of the drug.
The drug is not prescribed for children under the age of 15 years with acute respiratory infections caused by viral infections, because of the risk of Reye's syndrome (encephalopathy and acute fatty degeneration of the liver with acute development of liver failure).
With caution, the drug should be prescribed for gout, hyperuricemia in patients with a history of gastrointestinal ulcer (including gastric and duodenal ulcer) or gastrointestinal bleeding, impaired renal and hepatic function, bronchial asthma, chronic diseases respiratory organs, hay fever, polyposis of the nasal mucosa in case of allergic reactions to drugs (including NSAIDs), in the second trimester of pregnancy.
Use during pregnancy and lactation
The drug is contraindicated for use in the I and III trimesters of pregnancy. The use of salicylates in high doses in the first trimester is associated with an increased frequency of fetal developmental defects (split palate, heart defects). In the III trimester, the use of salicylates in high doses (more than 300 mg / day) causes inhibition of labor, premature closure of the ductus arteriosus in the fetus, increased bleeding in the mother and fetus, and administration immediately before birth can cause intracranial hemorrhages, especially in premature babies.
Prescribing in the second trimester of pregnancy is possible only after a careful assessment of the expected benefits to the mother and the potential risk to the fetus.
During lactation with prolonged use or when taking acetylsalicylic acid in high doses, breastfeeding should be discontinued. Accidental intake of salicylates during lactation does not require cessation of breastfeeding. Salicylates and their metabolites in small quantities are excreted in breast milk.
Composition
1 tablet contains 100 mg acetylsalicylic acid.
Dosage and administration of
Aspirin cardio is prescribed by mouth.
For prophylaxis in cases of suspected acute myocardial infarction, the recommended dose is 100-200 mg / day or 300 mg every other day. The first tablet is recommended to chew for faster absorption.
For the prevention of acute acute myocardial infarction in the presence of risk factors, the recommended dose is 100 mg / day or 300 mg every other day.
For the prevention of recurrent myocardial infarction, with unstable angina, for the prevention of stroke, transient cerebrovascular accident and thromboembolic complications after surgical procedures on the vessels, the drug is prescribed at a dose of 100-300 mg / day.
For the prevention of deep vein thrombosis and thromboembolism of the pulmonary artery and its branches, the recommended dose is 100-200 mg / day or 300 mg every other day.
Aspirin Cardio is intended for long-term use, the duration of therapy is set individually.
Aspirin Cardio tablets are taken before meals with plenty of fluids.
Side effects of
From the gastrointestinal tract: nausea, anorexia, pain in the epigastric region in some cases (especially with frequent and prolonged use of the drug) are possible - erosive and ulcerative lesions of the gastrointestinal tract, hidden blood loss from the gastrointestinal tract, signs of gastrointestinal bleeding (tarry stool )
From the hematopoietic system: very rarely - thrombocytopenia, anemia (due to hidden bleeding from the digestive tract).
Allergic reactions: rarely (especially in patients with bronchial asthma) - skin rash, bronchospasm.
Drug Interaction
When used together, Aspirin Cardio enhances the effects of methotrexate by reducing its renal clearance and displacing it from its association with blood plasma proteins.
With the simultaneous use of Aspirin Cardio, it enhances the action of heparin and indirect anticoagulants by disrupting platelet function and displacing indirect anticoagulants from blood plasma protein bonds.
Aspirin Cardio with combined use enhances the action of thrombolytic and antiplatelet drugs (including ticlopidine).
Aspirin Cardio by reducing renal clearance increases the concentration of digoxin in blood plasma and enhances its effects.
Aspirin Cardio enhances the effects of hypoglycemic drugs (insulin and sulfonylurea) due to the hypoglycemic effect of acetylsalicylic acid and the displacement of sulfonylurea derivatives from communication with blood plasma proteins.
When used together, Aspirin Cardio reduces the effect of uricosuric drugs (benzbromarone).
With the use of ACS, salicylate excretion is enhanced.
overdose
Symptoms: overdose of moderate severity - nausea, vomiting, tinnitus, hearing loss, dizziness, confusion in severe degree - fever, hyperventilation, ketoacoracid, hyperglycemia. Overdose is most likely in elderly patients.
Treatment: in case of overdose of moderate severity - reduction of the dose of the drug in severe - immediate hospitalization for emergency therapy - activated charcoal, gastric lavage, determination of acid-base balance, alkaline and forced alkaline diuresis, diuretic diarrhea, diuresis. When carrying out alkaline diuresis it is necessary to achieve pH values between 7.5-8. Forced alkaline diuresis should be performed at plasma salicylate concentrations greater than 500 mg / l (3.6 mmol / l) in adults and 300 mg / l (2.2 mmol / l) in children.
Storage conditions
The drug should be stored out of the reach of children at a temperature not exceeding 25 ° C.
Expiration
5 years.
Deystvuyuschee substances
Atsetylsalytsylovaya acid
pharmacy leave terms without a prescription
dosage form
dosage form
tablets
Aspirin cardio tablets 100 mg, 28 pcs. (Atsetylsalytsylovaya acid) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Aspirin cardio tablets 100 mg, 28 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.
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