Ascorbic acid twist currants, 10 pcs. (Askorbynovaya kyslota)

Release form

Tablets.

Packing

10 pcs.

Pharmacological action of

Replenishes the deficiency of vitamin C.

Indications

Vitamin deficiency and hypovitaminosis With

Hemorrhagic diathesis

Nasal, pulmonary, hepatic, uterine, and other bleeding

Infectious diseases and intoxications

Liver diseases

Addison's disease

Sluggish healing wounds, ulcers and broken bones

Dystrophy

Increased physical and mental stress sardlc

Contraindications

Thrombophlebitis

Tendency to thrombosis

with diabetes mellitus.

Special instructions

Absorption of ascorbic acid decreases with the use of hormonal contraceptives for oral administration, the use of fresh fruit or vegetable juices, alkaline drink.

Ascorbic acid increases the absorption of penicillin, reduces the effects of heparin, indirect anticoagulants, increases the risk of crystalluria during treatment with salicylates.

Ascorbic acid, due to its reducing properties, converts ferric to ferrous iron, which improves its absorption.

Composition

1 tablet contains:

Ascorbic acid 0.05 g

Dosage and administration

For preventive purposes, adults - 0.05-0.1 g per day during pregnancy, the postpartum period and in the case of low vitamin C content in the milk of nursing women - 0.3 g per day per for 10-15 days, after which prophylactically - 0.1 g per day for the entire lactation period. Children for prevention - 0.025 g 2-3 times a day.

Therapeutic doses for adults - 0.05-0.1 g 3-5 times a day. Children - 0.05-0.1 g 2-3 times a day.

Side effects

Allergic reactions, hypervitaminosis.

Drug Interactions

Pharmaceutically incompatible with aminophylline, bleomycin, cefazolin, cefapirin, chlordiazepoxide, estrogens, dextrans, doxapram, erythromycin, methicillin, nafcillin, benzylpenicin.

Increases the concentration in the blood of benzylpenicillin and tetracyclines at a dose of 1 g / day, increases the bioavailability of ethinyl estradiol (including that which is part of oral contraceptives). Reduces the effectiveness of heparin and indirect anticoagulants.

With simultaneous use with acetylsalicylic acid, urinary excretion of ascorbic acid increases and excretion of acetylsalicylic acid decreases.

Increases the risk of crystalluria in the treatment of short-acting salicylates and sulfanilamides, slows the excretion of acids by the kidneys, increases the excretion of drugs with an alkaline reaction (including alkaloids), and reduces the concentration of oral contraceptives in the blood. Increases the total clearance of ethanol, which in turn reduces the concentration of ascorbic acid in the body.

Quinoline drugs, calcium preparations, salicylates, glucocorticosteroids, with prolonged use, deplete ascorbic acid reserves.

With simultaneous use, it reduces the chronotropic effect of isoprenaline.

Long-term or high-dose use may interfere with the interaction of disulfiram and ethanol.

In high doses, increases the excretion of mexiletine by the kidneys.

Barbiturates and primidone increase urinary excretion of ascorbic acid.

Reduces the therapeutic effect of antipsychotic drugs (antipsychotics) - phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants.

Overdose

Symptoms with prolonged use of large doses (more than 1 g) - headache, increased excitability of the central nervous system, insomnia, nausea, vomiting, hyperacid gastritis, ulceration of the mucous membrane of the gastrointestinal tract, heartburn, diarrhea, difficulty urinating, urination. urine in red, hemolysis (in patients with a deficiency of glucose-6-phosphate dehydrogenase), inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria), hyperoxaluria, nephrolithiasis (from calcium ox alata), damage to the glomerular apparatus of the kidneys, moderate pollakiuria (when taking doses of more than 600 mg / day). Decreased capillary permeability (possibly worsening tissue trophism, increased blood pressure, hypercoagulation, the development of microangiopathies).

Storage Conditions

In a dry, dark place.

Expiration

2 years.

Active ingredient

Ascorbic acid

ma

tablets for resorption

Appointment

Vitamins and minerals

Farmindustry, Russia



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