Ascorbic acid ampoules 5%, 2 ml, 10 pcs. (Askorbynovaya kyslota)

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Release form

Injectable solution Buy Ascorbic acid ampoules 5%, 2 ml, 10 pcs. (Askorbynovaya kyslota) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Release form

Injectable solution

Packaging

In a package of 10 ampoules of 2 ml.

Pharmacological action of

Ascorbic acid replenishes the deficiency of vitamin C. It forms an ascorbic system - dehydroascorbic acid, which is involved in the transfer of hydrogen and regulates the recovery of a number of metabolites and the activity of the monooxygenase system.

Indications

Prevention and treatment of hypo- and vitamin deficiency vitamin C

As an adjuvant: hemorrhagic diathesis, nasal, uterine, pulmonary and other bleeding, radiation therapy, overdose of anticoagulants, infectious diseases and intoxications, liver diseases, nephros Addison's sluggishly healing wounds and bone fractures. dystrophy and other pathological processes.

The drug is prescribed for increased physical and mental stress, during pregnancy and breastfeeding, during recovery from severe long-term illnesses.

Contraindications

Hypersensitivity, with prolonged use in large doses (more than 500 mg) - diabetes, hyperoxaluria, nephrolithiasis, hemochromatosis, thalassemia, glucose-6-phosphate dehydrogenase deficiency.

Precautions

Sideroblastic anemia, urolithiasis.

Use during pregnancy and lactation

During pregnancy and lactation, use only if the intended benefit to the mother outweighs the potential risk to the fetus and the baby. The minimum daily requirement for ascorbic acid in the II-III trimesters of pregnancy is about 60 mg. It should be borne in mind that the fetus can adapt to high doses of ascorbic acid, which is taken by a pregnant woman, and then the withdrawal syndrome may develop in the newborn. The minimum daily need for lactation is 80 mg.

A mother’s diet containing an adequate amount of ascorbic acid is sufficient to prevent a baby’s deficiency. Theoretically, there is a danger to the child when the mother uses high doses of ascorbic acid (it is recommended not to exceed the daily requirement for ascorbic acid by the nursing mother).

Special instructions

In connection with the stimulating effect of ascorbic acid on the synthesis of corticosteroid hormones, it is necessary to monitor adrenal function and blood pressure. High doses of ascorbic acid enhance the excretion of oxalates, contributing to the formation of kidney stones. In newborns whose mothers took high doses of ascorbic acid, and in adults who took high doses, ricochet scurvy can be observed. With prolonged use of large doses, inhibition of the function of the insular apparatus of the pancreas is possible, therefore, during treatment it must be regularly monitored. In patients with a high iron content in the body, ascorbic acid should be used in minimal doses. As a reducing agent, ascorbic acid can distort the results of various laboratory tests (the content of glucose, bilirubin, the activity of hepatic transaminases and lactate dehydrogenase in the blood and urine).

Influence on the ability to drive vehicles and control mechanisms

During the treatment period, care must be taken when driving and engaging in potentially hazardous activities that require an increased concentration of attention and speed of psychomotor reactions.

Composition

1 ml injection contains: active substance: ascorbic acid 50 mg.

Dosage and administration

Therapeutic dose for adults with parenteral administration is 1-3 ml of a 5% solution (2-6 ml of a 2.5% solution) per day. Children are prescribed parenterally 1-2 ml of a 5% solution (2-4 ml of a 2.5% solution) per day.

The course of treatment depends on the nature and course of the disease.

Side effects

From the central nervous system: with rapid intravenous administration - dizziness, feeling tired, with prolonged use of large doses (more than 1 g) - headache, increased excitability of the central nervous system, insomnia.

From the urinary system: moderate pollakiuria (when using a dose of more than 600 mg / day), with prolonged use of large doses - hyperoxaluria, nephrolithiasis (from calcium oxalate), damage to the glomerular apparatus of the kidneys.

On the part of the cardiovascular system: with prolonged use of large doses, a decrease in capillary permeability (possibly worsening trophic tissue, increased blood pressure, hypercoagulation, the development of microangiopathies).

Allergic reactions: allergic reactions up to the development of anaphylactic shock.

Laboratory indicators: thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia, glucosuria.

Local reactions: pain at the site of intramuscular injection.

Other: with prolonged use of large doses (more than 1 g) - inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria), with intravenous administration - the threat of abortion (due to estrogenemia), erythrocyte hemolysis.

Drug Interactions

Pharmaceutically incompatible with aminophylline, bleomycin, cefazolin, cefapirin, chlordiazepoxide, estrogens, dextrans, doxapram, erythromycin, methicillin, nafcillin, benzylpenicillin, warfarin.

Increases the concentration in the blood of benzylpenicillin and tetracyclines at a dose of 1 g / day, increases the bioavailability of ethinyl estradiol (including that which is part of oral contraceptives). Reduces the effectiveness of heparin and indirect anticoagulants.

With simultaneous use with acetylsalicylic acid, urinary excretion of ascorbic acid increases and excretion of acetylsalicylic acid decreases.

Increases the risk of crystalluria in the treatment of short-acting salicylates and sulfanilamides, slows the excretion of acids by the kidneys, increases the excretion of drugs with an alkaline reaction (including alkaloids), and reduces the concentration of oral contraceptives in the blood. Increases the total clearance of ethanol, which in turn reduces the concentration of ascorbic acid in the body.

Quinoline drugs, calcium preparations, salicylates, glucocorticosteroids, with prolonged use, deplete ascorbic acid reserves.

With simultaneous use, it reduces the chronotropic effect of isoprenaline.

Long-term or high-dose use may interfere with the interaction of disulfiram and ethanol. In high doses, it increases the excretion of mexiletine by the kidneys. Barbiturates and primidone increase urinary excretion of ascorbic acid.

Reduces the therapeutic effect of antipsychotic drugs (antipsychotics) - phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants.

Overdose

Symptoms: nephrolithiasis, insomnia, irritability, hypoglycemia.

Treatment: symptomatic, forced diuresis.

Storage conditions

at a temperature above 15 ° C With

Shelf life

1 year.

Deystvuyushtee substance

Askorbinovaya kislota

Possible product names

Ascorbic acid 5% amp 2ml N10 Russia

Ascorbic acid ampoules 5%, 2 ml, 10 pcs.

Ascorbic acid solution for i.v.injection 50mg / ml 2ml N10 amp

Dalkhimpharm, Russia



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