Ascorbic acid ampoules 10%, 2 ml, 10 pcs. (Ascorbin Vai kyslota)
Special Price
$19.80
Regular Price
$20.00
In stock
SKU
florida512894
Release form
Injection. Buy Ascorbic acid ampoules 10%, 2 ml, 10 pcs. (Ascorbin Vai kyslota) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Injection. Buy Ascorbic acid ampoules 10%, 2 ml, 10 pcs. (Ascorbin Vai kyslota) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Release form
Injection.
Packing
In a package of 10 ampoules of 2 ml.
Pharmacological action of
Ascorbic acid has pronounced reducing properties, is involved in the regulation of carbohydrate metabolism, redox processes, blood coagulation, normalization of capillary permeability, tissue regeneration, synthesis of steroid hormones, collagen, procollagen.
Pharmacokinetics
Communication with plasma proteins - 25%. The concentration of ascorbic acid in plasma is normally approximately 10 to 20 μg / ml. It easily penetrates into white blood cells, platelets, and then - in all tissues, the highest concentration is achieved in glandular organs, white blood cells, liver and lens of the eye penetrates through the placenta. The concentration of ascorbic acid in leukocytes and platelets is higher than in red blood cells and in plasma. In deficient conditions, the concentration in leukocytes decreases later and more slowly and is considered as a better criterion for assessing deficiency than plasma concentration.
Metabolized mainly in the liver to deoxy-ascorbic acid and then to oxaloacetic acid and ascorbate-2-sulfate.
It is excreted by the kidneys, through the intestines, with sweat, breast milk unchanged and in the form of metabolites. With the appointment of high doses, the rate of excretion increases dramatically. Smoking and the use of ethanol accelerate the destruction of ascorbic acid (conversion into inactive metabolites), drastically reducing body reserves. It is excreted during hemodialysis.
Indications
Prevention and treatment of hypo- and vitamin deficiency vitamin C
As an adjuvant: hemorrhagic diathesis, nasal, uterine, pulmonary and other bleeding, against the background of radiation sickness, an overdose of anticoagulants, infectious diseases and intoxications, liver diseases, nephros Addison's sluggishly healing wounds and bone fractures. dystrophy and other pathological processes.
The drug is prescribed for increased physical and mental stress, during pregnancy and breastfeeding, during recovery from severe long-term illnesses.
Contraindications
Hypersensitivity, with prolonged use in large doses (more than 500 mg) - diabetes, hyperoxaluria, nephrolithiasis, hemochromatosis, thalassemia, glucose-6-phosphate dehydrogenase deficiency.
Precautions
Sideroblastic anemia, urolithiasis.
Use during pregnancy and lactation
During pregnancy and lactation, use only if the intended benefit to the mother outweighs the potential risk to the fetus and the baby. The minimum daily requirement for ascorbic acid in the II-III trimesters of pregnancy is about 60 mg. It should be borne in mind that the fetus can adapt to high doses of ascorbic acid, which is taken by a pregnant woman, and then the withdrawal syndrome may develop in the newborn. The minimum daily need for lactation is 80 mg.
mother’s diet, containing an adequate amount of ascorbic acid is sufficient to prevent its deficiency in the infant. Theoretically, there is a danger to the child when the mother uses high doses of ascorbic acid (it is recommended not to exceed the daily requirement for ascorbic acid by the nursing mother).
Special instructions
In connection with the stimulating effect of ascorbic acid on the synthesis of corticosteroid hormones, it is necessary to monitor adrenal function and blood pressure. High doses of ascorbic acid enhance the excretion of oxalates, contributing to the formation of kidney stones. In newborns whose mothers took high doses of ascorbic acid, and in adults who took high doses, ricochet scurvy can be observed. With prolonged use of large doses, inhibition of the function of the insular apparatus of the pancreas is possible, therefore, during treatment it must be regularly monitored. In patients with a high iron content in the body, ascorbic acid should be used in minimal doses. Ascorbic acid, as a reducing agent, may distort the results of various laboratory tests (blood and urine levels of glucose, bilirubin, activity of hepatic transaminases and lactate dehydrogenase).
Influence on the ability to drive vehicles and control mechanisms
During the treatment period, care must be taken when driving and engaging in potentially hazardous activities that require an increased concentration of attention and speed of psychomotor reactions.
Composition
1 ml of solution for injection contains: active substance: ascorbic acid 100 mg
Dosage and administration
Used as directed by a doctor. Ascorbic acid is prescribed intramuscularly or intravenously. For preventive purposes, adults are prescribed 0.05 g-0.1 g per day during pregnancy, in the postpartum period and in the case of a low vitamin C content in the milk of nursing women, 0.3 g per day is prescribed for 10-15 days, then prophylactically at 0.1 g per day for the entire period of lactation. Children are prescribed prophylactically at 0.025 g 2-3 times a day.
Therapeutic dose for adults with parenteral administration is 1-3 ml of a 5% solution (2-6 ml of a 2.5% solution) per day. Children are prescribed parenterally 1-2 ml of 5% solution (2-4 ml 2, 5% solution) per day.
The course of treatment depends on the nature and course of the disease.
Side effects of
From the central nervous system: with rapid intravenous administration - dizziness, feeling tired, with prolonged use of large doses (more than 1 g) - headache, increased excitability of the central nervous system, insomnia.
From the urinary system: moderate pollakiuria (when applying a dose of more than 600 mg / day), with prolonged use of large doses - hyperoxaluria, nephrolithiasis (from calcium oxalate), damage to the glomerular apparatus of the kidneys.
On the part of the cardiovascular system: with prolonged use of large doses, a decrease in capillary permeability (possibly worsening trophic tissue, increased blood pressure, hypercoagulation, the development of microangiopathies).
Allergic reactions: allergic reactions up to the development of anaphylactic shock.
Laboratory indicators: thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia, glucosuria.
Local reactions: pain at the site of intramuscular injection.
Other: with prolonged use of large doses (more than 1 g) - inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria), with intravenous administration - the threat of abortion (due to estrogenemia), erythrocyte hemolysis.
Drug Interactions
Pharmaceutically incompatible with aminophylline, bleomycin, cefazolin, cefapirin, chlordiazepoxide, estrogens, dextrans, doxapram, erythromycin, methicillin, nafcillin, benzylpenicillin, warfarin.
Increases the concentration in the blood of benzylpenicillin and tetracyclines at a dose of 1 g / day, increases the bioavailability of ethinyl estradiol (including that which is part of oral contraceptives). Reduces the effectiveness of heparin and indirect anticoagulants.
With simultaneous use with acetylsalicylic acid, urinary excretion of ascorbic acid increases and excretion of acetylsalicylic acid decreases.
Increases the risk of crystalluria in the treatment of short-acting salicylates and sulfanilamides, slows the excretion of acids by the kidneys, increases the excretion of drugs with an alkaline reaction (including alkaloids), and reduces the concentration of oral contraceptives in the blood. Increases the total clearance of ethanol, which in turn reduces the concentration of ascorbic acid in the body.
Quinoline drugs, calcium preparations, salicylates, glucocorticosteroids, with prolonged use, deplete ascorbic acid reserves.
With simultaneous use, it reduces the chronotropic effect of isoprenaline.
Long-term or high-dose use may interfere with the interaction of disulfiram and ethanol. In high doses, it increases the excretion of mexiletine by the kidneys. Barbiturates and primidone increase urinary excretion of ascorbic acid.
Reduces the therapeutic effect of antipsychotic drugs (antipsychotics) - phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants.
Overdose
Symptoms: nephrolithiasis, insomnia, irritability, hypoglycemia.
Treatment: symptomatic, forced diuresis.
Storage conditions
In a protected place from light at a temperature not exceeding 25 ° C
Shelf life
1 year.
Deystvuyushtee substance
Askorbinovaya kislota
Terms of drugstore
prescription
Indications
Indications of
Indications From infectious diseases, Varicose veins, From stress, From bleeding, Colds, Inadequate nutrition, Flu, From bone fractures
Ascorbic acid ampoules 10%, 2 ml, 10 pcs. (Ascorbin Vai kyslota) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Ascorbic acid ampoules 10%, 2 ml, 10 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.
Injection.
Packing
In a package of 10 ampoules of 2 ml.
Pharmacological action of
Ascorbic acid has pronounced reducing properties, is involved in the regulation of carbohydrate metabolism, redox processes, blood coagulation, normalization of capillary permeability, tissue regeneration, synthesis of steroid hormones, collagen, procollagen.
Pharmacokinetics
Communication with plasma proteins - 25%. The concentration of ascorbic acid in plasma is normally approximately 10 to 20 μg / ml. It easily penetrates into white blood cells, platelets, and then - in all tissues, the highest concentration is achieved in glandular organs, white blood cells, liver and lens of the eye penetrates through the placenta. The concentration of ascorbic acid in leukocytes and platelets is higher than in red blood cells and in plasma. In deficient conditions, the concentration in leukocytes decreases later and more slowly and is considered as a better criterion for assessing deficiency than plasma concentration.
Metabolized mainly in the liver to deoxy-ascorbic acid and then to oxaloacetic acid and ascorbate-2-sulfate.
It is excreted by the kidneys, through the intestines, with sweat, breast milk unchanged and in the form of metabolites. With the appointment of high doses, the rate of excretion increases dramatically. Smoking and the use of ethanol accelerate the destruction of ascorbic acid (conversion into inactive metabolites), drastically reducing body reserves. It is excreted during hemodialysis.
Indications
Prevention and treatment of hypo- and vitamin deficiency vitamin C
As an adjuvant: hemorrhagic diathesis, nasal, uterine, pulmonary and other bleeding, against the background of radiation sickness, an overdose of anticoagulants, infectious diseases and intoxications, liver diseases, nephros Addison's sluggishly healing wounds and bone fractures. dystrophy and other pathological processes.
The drug is prescribed for increased physical and mental stress, during pregnancy and breastfeeding, during recovery from severe long-term illnesses.
Contraindications
Hypersensitivity, with prolonged use in large doses (more than 500 mg) - diabetes, hyperoxaluria, nephrolithiasis, hemochromatosis, thalassemia, glucose-6-phosphate dehydrogenase deficiency.
Precautions
Sideroblastic anemia, urolithiasis.
Use during pregnancy and lactation
During pregnancy and lactation, use only if the intended benefit to the mother outweighs the potential risk to the fetus and the baby. The minimum daily requirement for ascorbic acid in the II-III trimesters of pregnancy is about 60 mg. It should be borne in mind that the fetus can adapt to high doses of ascorbic acid, which is taken by a pregnant woman, and then the withdrawal syndrome may develop in the newborn. The minimum daily need for lactation is 80 mg.
mother’s diet, containing an adequate amount of ascorbic acid is sufficient to prevent its deficiency in the infant. Theoretically, there is a danger to the child when the mother uses high doses of ascorbic acid (it is recommended not to exceed the daily requirement for ascorbic acid by the nursing mother).
Special instructions
In connection with the stimulating effect of ascorbic acid on the synthesis of corticosteroid hormones, it is necessary to monitor adrenal function and blood pressure. High doses of ascorbic acid enhance the excretion of oxalates, contributing to the formation of kidney stones. In newborns whose mothers took high doses of ascorbic acid, and in adults who took high doses, ricochet scurvy can be observed. With prolonged use of large doses, inhibition of the function of the insular apparatus of the pancreas is possible, therefore, during treatment it must be regularly monitored. In patients with a high iron content in the body, ascorbic acid should be used in minimal doses. Ascorbic acid, as a reducing agent, may distort the results of various laboratory tests (blood and urine levels of glucose, bilirubin, activity of hepatic transaminases and lactate dehydrogenase).
Influence on the ability to drive vehicles and control mechanisms
During the treatment period, care must be taken when driving and engaging in potentially hazardous activities that require an increased concentration of attention and speed of psychomotor reactions.
Composition
1 ml of solution for injection contains: active substance: ascorbic acid 100 mg
Dosage and administration
Used as directed by a doctor. Ascorbic acid is prescribed intramuscularly or intravenously. For preventive purposes, adults are prescribed 0.05 g-0.1 g per day during pregnancy, in the postpartum period and in the case of a low vitamin C content in the milk of nursing women, 0.3 g per day is prescribed for 10-15 days, then prophylactically at 0.1 g per day for the entire period of lactation. Children are prescribed prophylactically at 0.025 g 2-3 times a day.
Therapeutic dose for adults with parenteral administration is 1-3 ml of a 5% solution (2-6 ml of a 2.5% solution) per day. Children are prescribed parenterally 1-2 ml of 5% solution (2-4 ml 2, 5% solution) per day.
The course of treatment depends on the nature and course of the disease.
Side effects of
From the central nervous system: with rapid intravenous administration - dizziness, feeling tired, with prolonged use of large doses (more than 1 g) - headache, increased excitability of the central nervous system, insomnia.
From the urinary system: moderate pollakiuria (when applying a dose of more than 600 mg / day), with prolonged use of large doses - hyperoxaluria, nephrolithiasis (from calcium oxalate), damage to the glomerular apparatus of the kidneys.
On the part of the cardiovascular system: with prolonged use of large doses, a decrease in capillary permeability (possibly worsening trophic tissue, increased blood pressure, hypercoagulation, the development of microangiopathies).
Allergic reactions: allergic reactions up to the development of anaphylactic shock.
Laboratory indicators: thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia, glucosuria.
Local reactions: pain at the site of intramuscular injection.
Other: with prolonged use of large doses (more than 1 g) - inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria), with intravenous administration - the threat of abortion (due to estrogenemia), erythrocyte hemolysis.
Drug Interactions
Pharmaceutically incompatible with aminophylline, bleomycin, cefazolin, cefapirin, chlordiazepoxide, estrogens, dextrans, doxapram, erythromycin, methicillin, nafcillin, benzylpenicillin, warfarin.
Increases the concentration in the blood of benzylpenicillin and tetracyclines at a dose of 1 g / day, increases the bioavailability of ethinyl estradiol (including that which is part of oral contraceptives). Reduces the effectiveness of heparin and indirect anticoagulants.
With simultaneous use with acetylsalicylic acid, urinary excretion of ascorbic acid increases and excretion of acetylsalicylic acid decreases.
Increases the risk of crystalluria in the treatment of short-acting salicylates and sulfanilamides, slows the excretion of acids by the kidneys, increases the excretion of drugs with an alkaline reaction (including alkaloids), and reduces the concentration of oral contraceptives in the blood. Increases the total clearance of ethanol, which in turn reduces the concentration of ascorbic acid in the body.
Quinoline drugs, calcium preparations, salicylates, glucocorticosteroids, with prolonged use, deplete ascorbic acid reserves.
With simultaneous use, it reduces the chronotropic effect of isoprenaline.
Long-term or high-dose use may interfere with the interaction of disulfiram and ethanol. In high doses, it increases the excretion of mexiletine by the kidneys. Barbiturates and primidone increase urinary excretion of ascorbic acid.
Reduces the therapeutic effect of antipsychotic drugs (antipsychotics) - phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants.
Overdose
Symptoms: nephrolithiasis, insomnia, irritability, hypoglycemia.
Treatment: symptomatic, forced diuresis.
Storage conditions
In a protected place from light at a temperature not exceeding 25 ° C
Shelf life
1 year.
Deystvuyushtee substance
Askorbinovaya kislota
Terms of drugstore
prescription
Indications
Indications of
Indications From infectious diseases, Varicose veins, From stress, From bleeding, Colds, Inadequate nutrition, Flu, From bone fractures
Ascorbic acid ampoules 10%, 2 ml, 10 pcs. (Ascorbin Vai kyslota) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Ascorbic acid ampoules 10%, 2 ml, 10 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.
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