Artra tab. p / o captivity. # 120
Scope of the medicinal product
Musculoskeletal system
Release form
Tablet
Manufacturer country
USA
Package quantity, pcs
120
Way of introduction
Through the mouth
Release form, composition and packaging
Film-coated tablets from white to white with a yellowish tinge, interspersed, oval, biconvex, with ARTRA" engraving on one side, with a specific odor
1 tab.
chondroitin sodium sulfate 500 mg
glucosamine hydrochloride 500 mg
calcium sulfate disubstituted - 230 mg, microcrystalline cellulose - 185 mg, sodium croscarmellose - 80 mg, stearic acid - 70 mg, magnesium stearate - 10 mg
Shell composition: hydroxypropyl methylcellulose - 35 mg, titanium dioxide (E171) - 8.2 mg, triacetin - 6.8 mg
30 pcs.
- bottles made of high density polyethylene (1) - cardboard packs.
60 pcs.
- bottles made of high density polyethylene (1) - cardboard packs.
100 pieces.
- bottles made of high density polyethylene (1) - cardboard packs.
120 pcs.
- bottles made of high density polyethylene (1) - cardboard packs.
pharmachologic effect
Cartilage regeneration stimulator
Glucosamine and chondroitin sodium sulfate are involved in the biosynthesis of connective tissue, helping to prevent the destruction of cartilage, stimulating tissue regeneration.
The introduction of exogenous glucosamine enhances the production of cartilage matrix and provides nonspecific protection, incl.
from NSAIDs and GCS.
The drug has a moderate anti-inflammatory effect.
Chondroitin sodium sulfate, whether absorbed intact or as separate components, serves as an additional substrate for the formation of a healthy cartilage matrix.
Stimulates the formation of proteoglycans and collagen type II, and also protects the cartilage matrix from enzymatic degradation (by suppressing the activity of hyaluronidase) and from the damaging effects of free radicals
maintains the viscosity of synovial fluid, stimulates cartilage repair mechanisms and inhibits the activity of those enzymes (elastase, hyaluronidase) that break down cartilage.
When treating osteoarthritis, it relieves symptoms of the disease and reduces the need for NSAIDs.
Pharmacokinetics
Absorption The bioavailability of glucosamine when taken orally is 25% (due to the "first pass" effect through the liver).
Bioavailability of chondroitin sulfate - 13%
Distribution Distributed in tissues: the highest concentrations of glucosamine are found in the liver, kidneys and articular cartilage.
About 30% of the dose taken persists for a long time in bone and muscle tissue
Excretion Glucosamine is excreted mainly in the urine unchanged
partly with feces.
T1 / 2 glucosamine - 68 hours
Indications for use
osteoarthritis of the peripheral joints and spine.
Contraindications for use
severe renal dysfunction
hypersensitivity to drug components
With care: bleeding or bleeding tendency, bronchial asthma, diabetes mellitus.
Dosage regimen
Inside, adults and children over 15 years of age are prescribed 1 tab.
2 times / day for the first three weeks
1 tab.
1 time / day for the next weeks and months
A stable therapeutic effect is achieved when taking the drug for at least 6 months.
Overdose
To date, no cases of Artra drug overdose have been reported
Treatment: gastric lavage, symptomatic therapy.
Side effect
Glucosamine From the digestive system: possible mild gastrointestinal dysfunction - epigastric pain, flatulence, diarrhea, constipation
From the side of the central nervous system: dizziness
Glucosamine and chondroitin Other: allergic reactions.
Drug interactions
With simultaneous use, it is possible to enhance the action of anticoagulants and antiplatelet agents
Artra increases the absorption of tetracyclines, reduces the effect of semi-synthetic penicillins
The drug is compatible with GCS.
Application during pregnancy and lactation
Artra is not recommended for use during pregnancy and lactation.
Special instructions Use in pediatrics CL
Name ENG
ARTRA
Clinical and pharmacological group
A drug that stimulates the regeneration of cartilage tissue
ATX code
Other drugs for the treatment of diseases of the musculoskeletal system
Dosage
500mg + 500mg
Structure
Active active ingredients: Glucosamine hydrochloride 500 mg Chondroitin sodium sulfate 500 mg Excipients: calcium phosphate disubstituted, microcrystalline cellulose, sodium croscarmellose, stearic acid, magnesium stearate.
Sheath: Hydroxypropyl methylcellulose, titanium dioxide (E171), triacetin.
Indications
Osteoarthritis of the peripheral joints and spine.
INN / Active ingredient
chondroitin sodium sulfate, glucosamine hydrochloride
Contraindications
Hypersensitivity, severe renal dysfunction.
With care: bleeding or bleeding tendency, bronchial asthma, diabetes mellitus.
Storage conditions and periods
At a temperature not higher than 25 degrees.
Expiration date: 2 years
Specifications
Scope of the medicinal product
Musculoskeletal system
Release form
Tablet
Manufacturer country
USA
Package quantity, pcs
120
Way of introduction
Through the mouth
Vacation conditions
Without recipe
Brand name
Unipharm
The amount of the dosage form in the primary package
120 pcs.
Primary packaging type
Bottle
Type of consumer packaging
Pack of cardboard
Pharmaco-therapeutic group
Tissue repair stimulant
Dosage form
Film-coated tablets
Expiration date in days
730
Package weight, g
295
Category
:
Joints
,
Treatment of diseases of the musculoskeletal system
,
Synovial fluid
,
Bone metabolism
Mode of application
:
Inside.
Adults and children over 15 years of age are prescribed 1 tab.
2 times a day for the first three weeks
1 tab.
1 time / day for the next weeks and months.
A stable therapeutic effect is achieved when the drug is taken for at least 6 months.
Anatomical and therapeutic characteristics
:
M09AX Other drugs for the treatment of diseases of the musculoskeletal system
Dosage (volume) of the substance in the preparation
:
1 tab .: glucosamine hydrochloride 500 mg, chondroitin sodium sulfate 500 mg
Information on technical characteristics, delivery set, country of manufacture "