Arbidol Maximum caps. 200mg # 10

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In stock
SKU
FL102014635
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Category

Antiviral

,

Antimicrobial agents

Scope of the medicinal product

General

Release form

Capsules

Manufacturer country

Russia

Package quantity, pcs

ten

Description

Release form, composition and packaging

?

Hard gelatin capsules, No. 0, white

contents of capsules - a mixture containing granules and powder from white or white with a greenish-yellow or cream shade of color to light yellow or light yellow with a greenish shade.

1 caps.

umifenovir hydrochloride (as umifenovir hydrochloride monohydrate) 200 mg

potato starch - 52.67 mg, microcrystalline cellulose - 11.2 mg, colloidal silicon dioxide (aerosil) - 2.8 mg, povidone (kollidon 25) - 7.73 mg, calcium stearate - 2.8 mg, croscarmellose sodium - 2.8 mg

the mass of the contents of the capsule is 280 mg.

The composition of the capsule shell (body and lid): titanium dioxide (E171) - 1.92 mg, gelatin - 94.08 mg

the total weight of the capsule is 376 mg.

10 pieces.

- contour cell packaging (1) - cardboard packs.

10 pieces.

- contour cell packages (2) - cardboard packs.

pharmachologic effect

Antiviral drug. Specifically suppresses in vitro influenza A and B viruses (Influenza virus A, B), including highly pathogenic subtypes A (H1N1) pdm09 and A (H5N1), as well as other viruses that cause ARVI (Coronavirus associated with severe acute respiratory syndrome (SARS), rhinovirus (Rhinovirus), adenovirus (Adenovirus), respiratory syncytial virus (Pneumovirus) and parainfluenza virus (Paramyxovirus)). According to the mechanism of antiviral action, it belongs to fusion inhibitors (fusion), interacts with the hemagglutinin of the virus and prevents the fusion of the lipid membrane of the virus and cell membranes. It has a moderate immunomodulatory effect, increases the body's resistance to viral infections. It has interferon-inducing activity - in a study on mice, the induction of interferons was noted after 16 hours,and high titers of interferons remained in the blood up to 48 hours after administration. Stimulates cellular and humoral reactions of immunity: increases the number of lymphocytes in the blood, especially T-cells (CD3), increases the number of T-helpers (CD4), without affecting the level of T-suppressors (CD8), normalizes the immunoregulatory index, stimulates the phagocytic function of macrophages and increases the number of natural killer cells (NK cells). Therapeutic efficacy for viral infections is manifested in a decrease in the duration and severity of the course of the disease and its main symptoms, as well as in a decrease in the incidence of complications associated with a viral infection and exacerbations of chronic bacterial diseases. Refers to low-toxic drugs (LD50> 4 g / kg).Does not have any negative effect on the human body when taken orally in recommended doses.

Pharmacokinetics

Absorption and distribution Rapidly absorbed and distributed to organs and tissues.

Cmax in blood plasma when taken at a dose of 50 mg is achieved after 1.2 hours, at a dose of 100 mg - after 1.5 hours. Metabolism and excretion Metabolized in the liver.

T1 / 2 is 17-21 hours. About 40% is excreted unchanged, mainly with bile (38.9%) and in a small amount by the kidneys (0.12%).

During the first day, 90% of the administered dose is removed.

Indications for use

- prevention and treatment in adults and children from 12 years of age: influenza A and B, ARVI (including those complicated by bronchitis, pneumonia), severe acute respiratory syndrome (SARS)

- complex therapy of acute intestinal infections of rotavirus etiology in children over 12 years old

- complex therapy of chronic bronchitis, pneumonia and recurrent herpes infection

- prevention of postoperative infectious complications.

Contraindications for use

- hypersensitivity to the drug

- children under 12 years old.

Dosage regimen

Inside, before meals.

Single dose for adults and children over 12 years old - 200 mg (1 capsule).

For non-specific prevention and treatment of influenza and other acute respiratory viral infections Non-specific prevention of influenza and other acute respiratory viral infections: - for non-specific prevention during an epidemic of influenza and other acute respiratory viral infections - 200 mg (1 ka

Name ENG

ARBIDOL MAXIMUM

Clinical and pharmacological group

Antiviral drug

ATX code

Umifenovir

Dosage

200mg

Structure

1 capsule contains: active substance: umifenovir.

Indications

prevention and treatment in adults and children from 12 years of age: influenza A and B, ARVI (including those complicated by bronchitis, pneumonia), severe acute respiratory syndrome (SARS)

complex therapy of acute intestinal infections of rotavirus etiology in children over 12 years old

complex therapy of chronic bronchitis, pneumonia and recurrent herpes infection

prevention of postoperative infectious complications.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 2 years

INN / Active ingredient

umifenovir hydrochloride

Contraindications

hypersensitivity to the drug

children under 12 years of age.

Specifications

Category

Antiviral

,

Antimicrobial agents

Scope of the medicinal product

General

Release form

Capsules

Manufacturer country

Russia

Package quantity, pcs

ten

Minimum age from

3 years old

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

OTCPharm

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antiviral agent

Anatomical and therapeutic characteristics

J05AX13 Umifenovir

Dosage form

Capsules

Expiration date in days

730

The target audience

Children

Dosage (volume) of the substance in the preparation

200 mg

Package weight, g

ten

Mode of application

:

Inside, before meals.

Single dose: children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg (2 capsules of 100 mg or 4 capsules of 50 mg).

Information on technical characteristics, delivery set, country of manufacture

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