Andipal tablets 20 pcs. (bendazole, Metamizol sodium, papaverine, Phenobarbital)

Dosage form

Tablets

Pharmacological action

Antispasmodic, analgesic.

Pharmacokinetics: Andipal consists of metamizole sodium (250 mg), bendazole (20 mg), papaverine hydrochloride (20 mg) and phenobarbital (20 mg). Each of the components of Andipal has a certain effect on the body. Metamizole sodium - has analgesic and anti-inflammatory effects. It is well and easily absorbed, the effect of its use quickly enough occurs. Bendazole or Dibazole - is able to dilate blood vessels, relieve spasms and lower blood pressure. In addition, the drug has a stimulating effect on spinal cord function. Dibazole is an immunostimulating drug. The main application is spasms in the organs of the gastrointestinal tract and blood vessels, the treatment of certain diseases of the nervous system. Papaverine hydrochloride - relieves spasm of internal organs, as well as blood vessels. Large doses of the drug can lead to a decrease in the excitability of the heart muscle and a slowdown in intracardiac conduction. Phenobarbital - has sleeping pills. Also applies to antiepileptic drugs. In small doses, it has a calming effect, in combination with antispasmodics and analgesics, it is used to treat smooth muscle spasms of internal organs.

Indications

Pain, associated with mild spasms of peripheral vessels and cerebral vessels:

mild forms of hypertension

migraine.

Contraindications

hypersensitivity to the components of the drug

glucose-6-phosphate dehydrogenase deficiency

impaired AV conduction

severe liver and kidney dysfunction

blood disease

myasthenia srdlp pregnancy srdlp pregnancy srdlp

Special instructions

According to the instructions, Andipal should not be taken with alcohol, since the drug is able to enhance the action of ethyl alcohol. The use of Andipal in combination with drugs that inhibit the nervous system can enhance their effect.

Composition

1 tablet contains:

active substances - metamizole sodium - 250 mg, phenobarbital - 20 mg, dibazole (bendazole) - 20 mg, papaverine hydrochloride - 20 mg

excipients: potato starch, talc, stearic acid.

Dosage and Administration

Inside. Adults - 1-2 tablets. 2-3 times a day. The course of treatment is 7-10 days.

If treatment is ineffective, the drug should be replaced or combined with other drugs (to achieve a hypotensive effect).

Side effects

Sometimes nausea, constipation, allergic reactions (up to anaphylactic shock) occur. With prolonged use of the drug, a depressing effect on the blood is possible due to the presence of analgin (leukopenia, rarely - agranulocytosis, thrombocytopenia). Phenobarbital, which is present in the composition of the drug, can have a sedative effect, sometimes ataxia and depression may occur (especially in elderly and debilitated patients).

Drug interaction

Pharmacological: combination with nitrates (Nitroglycerin, Nitrosorbid, Sustak, etc.), BKK (Nifedipine, Corinfar), amiodarone, beta-blockers (Anaprilin, metoprolol, oxprenol talinolol, etc.), ganglion blockers (pentamine, etc.), diuretics (Furosemide, Hypothiazide, etc.), myotropic antispasmodics (dipyridamole, aminophylline, etc.) enhances the hypotensive effect of Andipal.

Combined use of direct (epinephrine, norepinephrine, and other) adrenergic agonists and indirect (ephedrine) type of action, n- and m-, n-cholinomimetics (nicotine, acetylcholine, etc.), analeptics (camphor, sulfocamphocaine, cordiamine, bemegrid, lobelin , cytisine, etc.), tonic agents (ginseng root, eleutherococcus extract, rhodiola extract, etc.) and Andipal reduces the hypotensive effect of the latter.

Pharmacokinetic: the combined use of activated carbon, astringents and enveloping agents reduces the absorption of the drug in the digestive tract.

Overdose

Symptoms: with an overdose, severe drowsiness, dizziness, collaptoid state occur.

Treatment: first aid - gastric lavage, intake of activated charcoal. Symptomatic Therapy

Active ingredient

Bendazole, Metamizole sodium oia, papaverine, Phenobarbital

Terms and conditions

without prescription

orma

tablet

Appointment

Adult

Pharmstandard-Leksredstva, Russia



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