Analgin-Ultra tablets is covered.pl.ob. 500 mg 20 pcs. (Metamizole Sodium)

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Latin name

Analgin-Ultra Buy Analgin-Ultra tablets is covered.pl.ob. 500 mg 20 pcs. (Metamizole Sodium) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Latin name

Analgin-Ultra

Release form

film-coated tablets

Pharmacological action

Analgesic-antipyretic. It is a derivative of pyrazolone. It has an analgesic, antipyretic and anti-inflammatory effect, the mechanism of which is associated with inhibition of prostaglandin synthesis.

Pharmacokinetics

After oral administration, metamizole sodium is rapidly hydrolyzed in the gastric juice to form the active metabolite 4-methyl-amino-antipyrine, which, after absorption, is metabolized to 4-formyl-amino-antipyrine and other metabolites.

After iv administration, metamizole sodium quickly becomes unavailable for determination.

Metamizole sodium metabolites do not bind to plasma proteins. Most of the dose is excreted in the urine in the form of metabolites. Metabolites are excreted in breast milk.

Indications

Pain syndrome of various origins (renal and biliary colic, neuralgia,

myalgia for injuries, burns, after

operations, headache, toothache, menalgia).

Fever for infectious and inflammatory diseases.

Contraindications

Severe renal and / or liver dysfunction, glucose-6-phosphate dehydrogenase deficiency, blood diseases, hypersensitivity to pyrazolone derivatives.

Use during pregnancy and lactation

Use with caution during pregnancy, especially in the first trimester and in the last 6 weeks.

Special instructions

With prolonged use, the picture of peripheral blood must be monitored.

Metamizole sodium is used in combination with pitophenone and fenpiverinium bromide as an analgesic with an antispasmodic effect.

Use with caution in children in the first 3 months of life.

Composition

1 tab. - metamizole sodium 500 mg

Dosage and administration

Inside or rectally, adults are prescribed 250-500 mg 2-3 times / day. The maximum single dose is 1 g, the daily dose is 3 g.

Single doses for children aged 2-3 years are 50-100 mg 4-5 years old - 100-200 mg 6-7 years old - 200 mg 8-14 years old - 250 -300 mg frequency of administration - 2-3 times / day.

Intramuscularly or intravenously slowly in adults - 250-500 mg 2-3 times / day. The maximum single dose is 1 g, the daily dose is 2 g. In children, parenteral doses of 50-100 mg per 10 kg of body weight are used.

Side effects

Allergic reactions: skin rash, Quincke's edema rarely - anaphylactic shock.

From the hematopoietic system: rarely, with prolonged use - leukopenia, agranulocytosis.

Local reactions: with i / m administration - infiltrates at the injection site.

Drug Interactions

With simultaneous use with analgesics, antipyretics, NSAIDs, mutual reinforcement of toxic effects is possible.

With simultaneous use with inducers of microsomal liver enzymes, a decrease in the effectiveness of metamizole sodium is possible.

With simultaneous use, the activity of indirect anticoagulants, oral hypoglycemic drugs, glucocorticoids, indomethacin increases due to their displacement from communication with blood proteins under the influence of metamizole sodium.

With simultaneous use with phenothiazine derivatives, pronounced hyperthermia with sedatives, anxiolytics is possible - the analgesic effect of sodium metamizole with tricyclic antidepressants, oral contraceptives, allopurinol is enhanced - the metabolism of sodium metamizole is disturbed and its toxicity with caffeine is increased, its concentration with caffeine is decreased - sodium caffeine is increased, its concentration is decreased with caffeine cyclosporine in blood plasma.

When metamizole sodium is used in combination with pitophenone hydrochloride (it has a direct myotropic effect on the smooth muscles of internal organs and causes it to relax) and fenpiverinium bromide (m-anticholinergic blocker), their pharmacological action is mutually reinforced, which is accompanied by a decrease in pain and relaxation of smooth muscles and a decrease in elevated body temperature.

Active ingredient

Metamizole sodium

Terms and conditions

without prescription

dosage form

tablets

Appointment

Prescription doctor, Pregnant doctor, Adult doctor prescribing, Children over 16 df4 doctor's appointment, Pregnant only 2nd trimester by doctor's appointment, Children over 15 years old, Adult

Indications

Neuritis, Cholelithiasis, Cholelithiasis acne, Radiculitis, Arthritis, Colds, Flu



Analgin-Ultra tablets is covered.pl.ob. 500 mg 20 pcs. (Metamizole Sodium) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Analgin-Ultra tablets is covered.pl.ob. 500 mg 20 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.

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