Analgin ampoules 500mg / ml, 2 ml, 10 pcs (metamizol sodium)
Special Price
$20.79
Regular Price
$21.00
In stock
SKU
florida477512
Release form
Injection Buy Analgin ampoules 500mg / ml, 2 ml, 10 pcs (metamizol sodium) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Injection Buy Analgin ampoules 500mg / ml, 2 ml, 10 pcs (metamizol sodium) in florida free shipping. Fast international shipping USA, AU, EU, UK and others.
Release form
Injection
Packing
10 ampoules of 2 ml.
Pharmacological action of
Analgin non-selectively blocks cyclooxygenase and reduces the formation of prostaglandins from arachidonic acid, interferes with pain extra- and proprioceptive impulses. Analgin has a slightly pronounced anti-inflammatory effect, which causes a small effect on water-salt metabolism (sodium and water retention) and the gastrointestinal mucosa. It has an antispasmodic effect on the smooth muscles of the urinary and biliary tract. The action develops 20-40 minutes after ingestion.
Pharmacokinetics of
After intravenous administration, the elimination half-life for metamizole sodium is 14 minutes. Approximately 96% is excreted in the urine as metabolites. The relationship of the active metabolite with plasma proteins is 50-60%. Mostly excreted by the kidneys.
Indications
Pain syndrome (mild to moderate): incl. headache, migraine, toothache, neuralgia, myalgia, radicular syndrome, algomenorrhea in the kidney, hepatic and biliary colic (in combination with antispasmodics).
Analgin can be used to reduce pain after surgical and diagnostic procedures.
Elevated body temperature in colds and other infectious and inflammatory diseases. The feasibility of using the drug is decided in each case, depending on the severity, nature and tolerance of the fever.
Contraindications
hypersensitivity to pyrazolone derivatives (propiphenazone, phenazone or phenylbutazone)
bronchial asthma induced by acetylsalicylic acid, salicylates or other non-steroidal anti-inflammatory drugs, including in the anamnesis), condition after ACG intestines, anemia, leukopenia
hereditary hemolytic anemia associated with deficiency of glucose-6-phosphate dehydrogenase
pregnancy (especially in I trimester e and in the last 6 weeks), lactation
infancy (up to 3 months, weighing less than 5 kg).
Use during pregnancy and lactation
During the first and last three months of pregnancy, you should not take Analgin. From the fourth to the sixth month of pregnancy, Analgin should be taken for strict medical reasons. After taking Analginum, breast-feeding should be stopped for 48 hours.
Special instructions
In patients suffering from bronchial asthma and pollinosis, hypersensitivity reactions may develop.
With prolonged use (more than 7 days), it is necessary to control the picture of peripheral blood. Against the background of taking metamizole sodium, agranulocytosis may develop, in connection with which, if there is an unmotivated rise in temperature, chills, sore throat, difficulty swallowing, stomatitis, erosive and ulcerative lesions of the oral cavity, vaginitis or proctitis, immediate withdrawal of the drug is necessary.
Do not use to relieve acute abdominal pain (until the cause is clarified).
To reduce the risk of adverse events from the gastrointestinal tract, use the lowest effective dose with the lowest possible short course.
In the treatment of patients receiving cytotoxic drugs, metamizole sodium should be administered only under medical supervision.
Intramuscular injection requires the use of a long needle.
Composition
1 ml injection contains: active substance: metamizole sodium (analgin) 500 mg,
injections excipients: up to 1 ml.
Dosage and administration
Adults and adolescents 15 years of age and over: 1-2 ml of Analgin solution 500 mg / ml or 2-4 ml of Analgin solution 250 mg / ml (intramuscularly or intravenously) is recommended as a single dose, the daily dose may make up to 4-8 ml of an injection solution of 500 mg / ml or an injection solution of 250 mg / ml (not more than 2 g), divided into 2-3 doses. The maximum single dose can be 1 g (2 ml of a solution of 500 mg / ml or 4 ml of a solution of 250 mg / ml).
Children and infants: Analgin should not be administered to newborns under the age of 3 months or with a body weight of less than 5 kg.
For children, Analgin is prescribed at a dose of 5-10 mg per 1 kg of body weight (0.1-0.2 ml of a solution of 500 mg / ml or 0.2-0.4 ml of a solution of 250 mg / ml).
A single dose can be prescribed up to 2-3 times a day.
Before administration, it is recommended to heat the solution to body temperature.
For children aged 3-12 months, administration is carried out only intramuscularly! (body weight of the child from 5 to 9 kg).
If the drug is administered too quickly, a critical drop in blood pressure and shock can occur. Intravenous administration should be carried out slowly (the rate of administration is not more than 1 ml (500 mg of metamizole sodium per minute)) in the supine position, while monitoring blood pressure, pulse and respiratory rate.
Since there is a fear that the drop in blood pressure of non-allergic genesis is dose-dependent, an amount of Analgin solution of more than 2 ml (1 g) should be administered with extreme caution.
Side effects of
From the urinary system: impaired renal function, oliguria, anuria, proteinuria, very rarely the development of acute interstitial nephritis, staining of urine in red (due to the release of the metabolite - rubazonic acid).
Allergic reactions: urticaria, including on the conjunctiva and mucous membranes of the nasopharynx, Quincke's edema in rare cases - malignant exudative erythema (Stevens-Johnson syndrome), anaphylactic shock, toxic epidermal necrolysis (Lyell syndrome), bronchospastic syndrome (not only with a tendency to bronchospasm).
From the hemopoietic organs: leukopenia, rarely agranulocytosis and thrombocytopenia of immune origin.
Other: possible decrease in blood pressure, heart rhythm disturbance.
Local reactions: intramuscular administration may result in infiltrates at the injection site.
Drug Interactions
The simultaneous use of Analgin with other non-narcotic analgesics can lead to a mutual increase in toxic effects.
Tricyclic antidepressants, contraceptives for oral administration and allopurinol disrupt the metabolism of metamizole sodium in the liver and increase its toxicity.
Barbiturates and phenylbutazone weaken the action of Analgin.
Analgin enhances the effects of alcohol-containing drinks.
Radiopaque drugs, colloidal blood substitutes, and penicillin should not be used during treatment with metamizole sodium.
Metamizole sodium, displacing oral hypoglycemic drugs, indirect anticoagulants, glucocorticosteroids and indomethacin from the protein bond, increases their activity.
The simultaneous use of analgin with cyclosporine reduces the level of the latter in the blood.
Thiamazole and sarcolisin increase the risk of developing leukopenia.
The effect is enhanced by codeine, H2-histamine receptor blockers, propranolol (slows inactivation).
Sedatives and tranquilizers enhance the analgesic effect of Analgin.
Myelotoxic drugs enhance the hematotoxicity of the drug.
Due to the high likelihood of pharmaceutical incompatibility, metamizole should not be mixed with other drugs in the same syringe.
overdose
In case of overdose, consult a doctor. The following symptoms may occur: nausea, vomiting, stomach pain, oliguria, hypothermia, decreased blood pressure, tachycardia, dyspnea, tinnitus, drowsiness, delirium, unconsciousness, acute agranulocytosis, hemorrhagic syndrome, acute or acute convulsions, paralysis of respiratory muscles.
Treatment: symptomatic. There is no specific antidote for sodium metamizole. In the conditions of the medical institution - carrying out forced diuresis, hemodialysis, in the development of convulsive syndrome - intravenous injection of diazepam and high-speed barbiturates.
Storage conditions
In a place protected from light, out of reach of children, at a temperature not exceeding 25 ° C
Terms leave through pharmacies
In retseptu
Dosage form
solution for injection and infusions
fairfavf19f20f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f25f19f19f19f19f19f19f19f19f25f19f19f25f Sky Factory, Russia
Analgin ampoules 500mg / ml, 2 ml, 10 pcs (metamizol sodium) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Analgin ampoules 500mg / ml, 2 ml, 10 pcs - Sale. PayPal accept. Free shipping florida. Fast international shipping.
Injection
Packing
10 ampoules of 2 ml.
Pharmacological action of
Analgin non-selectively blocks cyclooxygenase and reduces the formation of prostaglandins from arachidonic acid, interferes with pain extra- and proprioceptive impulses. Analgin has a slightly pronounced anti-inflammatory effect, which causes a small effect on water-salt metabolism (sodium and water retention) and the gastrointestinal mucosa. It has an antispasmodic effect on the smooth muscles of the urinary and biliary tract. The action develops 20-40 minutes after ingestion.
Pharmacokinetics of
After intravenous administration, the elimination half-life for metamizole sodium is 14 minutes. Approximately 96% is excreted in the urine as metabolites. The relationship of the active metabolite with plasma proteins is 50-60%. Mostly excreted by the kidneys.
Indications
Pain syndrome (mild to moderate): incl. headache, migraine, toothache, neuralgia, myalgia, radicular syndrome, algomenorrhea in the kidney, hepatic and biliary colic (in combination with antispasmodics).
Analgin can be used to reduce pain after surgical and diagnostic procedures.
Elevated body temperature in colds and other infectious and inflammatory diseases. The feasibility of using the drug is decided in each case, depending on the severity, nature and tolerance of the fever.
Contraindications
hypersensitivity to pyrazolone derivatives (propiphenazone, phenazone or phenylbutazone)
bronchial asthma induced by acetylsalicylic acid, salicylates or other non-steroidal anti-inflammatory drugs, including in the anamnesis), condition after ACG intestines, anemia, leukopenia
hereditary hemolytic anemia associated with deficiency of glucose-6-phosphate dehydrogenase
pregnancy (especially in I trimester e and in the last 6 weeks), lactation
infancy (up to 3 months, weighing less than 5 kg).
Use during pregnancy and lactation
During the first and last three months of pregnancy, you should not take Analgin. From the fourth to the sixth month of pregnancy, Analgin should be taken for strict medical reasons. After taking Analginum, breast-feeding should be stopped for 48 hours.
Special instructions
In patients suffering from bronchial asthma and pollinosis, hypersensitivity reactions may develop.
With prolonged use (more than 7 days), it is necessary to control the picture of peripheral blood. Against the background of taking metamizole sodium, agranulocytosis may develop, in connection with which, if there is an unmotivated rise in temperature, chills, sore throat, difficulty swallowing, stomatitis, erosive and ulcerative lesions of the oral cavity, vaginitis or proctitis, immediate withdrawal of the drug is necessary.
Do not use to relieve acute abdominal pain (until the cause is clarified).
To reduce the risk of adverse events from the gastrointestinal tract, use the lowest effective dose with the lowest possible short course.
In the treatment of patients receiving cytotoxic drugs, metamizole sodium should be administered only under medical supervision.
Intramuscular injection requires the use of a long needle.
Composition
1 ml injection contains: active substance: metamizole sodium (analgin) 500 mg,
injections excipients: up to 1 ml.
Dosage and administration
Adults and adolescents 15 years of age and over: 1-2 ml of Analgin solution 500 mg / ml or 2-4 ml of Analgin solution 250 mg / ml (intramuscularly or intravenously) is recommended as a single dose, the daily dose may make up to 4-8 ml of an injection solution of 500 mg / ml or an injection solution of 250 mg / ml (not more than 2 g), divided into 2-3 doses. The maximum single dose can be 1 g (2 ml of a solution of 500 mg / ml or 4 ml of a solution of 250 mg / ml).
Children and infants: Analgin should not be administered to newborns under the age of 3 months or with a body weight of less than 5 kg.
For children, Analgin is prescribed at a dose of 5-10 mg per 1 kg of body weight (0.1-0.2 ml of a solution of 500 mg / ml or 0.2-0.4 ml of a solution of 250 mg / ml).
A single dose can be prescribed up to 2-3 times a day.
Before administration, it is recommended to heat the solution to body temperature.
For children aged 3-12 months, administration is carried out only intramuscularly! (body weight of the child from 5 to 9 kg).
If the drug is administered too quickly, a critical drop in blood pressure and shock can occur. Intravenous administration should be carried out slowly (the rate of administration is not more than 1 ml (500 mg of metamizole sodium per minute)) in the supine position, while monitoring blood pressure, pulse and respiratory rate.
Since there is a fear that the drop in blood pressure of non-allergic genesis is dose-dependent, an amount of Analgin solution of more than 2 ml (1 g) should be administered with extreme caution.
Side effects of
From the urinary system: impaired renal function, oliguria, anuria, proteinuria, very rarely the development of acute interstitial nephritis, staining of urine in red (due to the release of the metabolite - rubazonic acid).
Allergic reactions: urticaria, including on the conjunctiva and mucous membranes of the nasopharynx, Quincke's edema in rare cases - malignant exudative erythema (Stevens-Johnson syndrome), anaphylactic shock, toxic epidermal necrolysis (Lyell syndrome), bronchospastic syndrome (not only with a tendency to bronchospasm).
From the hemopoietic organs: leukopenia, rarely agranulocytosis and thrombocytopenia of immune origin.
Other: possible decrease in blood pressure, heart rhythm disturbance.
Local reactions: intramuscular administration may result in infiltrates at the injection site.
Drug Interactions
The simultaneous use of Analgin with other non-narcotic analgesics can lead to a mutual increase in toxic effects.
Tricyclic antidepressants, contraceptives for oral administration and allopurinol disrupt the metabolism of metamizole sodium in the liver and increase its toxicity.
Barbiturates and phenylbutazone weaken the action of Analgin.
Analgin enhances the effects of alcohol-containing drinks.
Radiopaque drugs, colloidal blood substitutes, and penicillin should not be used during treatment with metamizole sodium.
Metamizole sodium, displacing oral hypoglycemic drugs, indirect anticoagulants, glucocorticosteroids and indomethacin from the protein bond, increases their activity.
The simultaneous use of analgin with cyclosporine reduces the level of the latter in the blood.
Thiamazole and sarcolisin increase the risk of developing leukopenia.
The effect is enhanced by codeine, H2-histamine receptor blockers, propranolol (slows inactivation).
Sedatives and tranquilizers enhance the analgesic effect of Analgin.
Myelotoxic drugs enhance the hematotoxicity of the drug.
Due to the high likelihood of pharmaceutical incompatibility, metamizole should not be mixed with other drugs in the same syringe.
overdose
In case of overdose, consult a doctor. The following symptoms may occur: nausea, vomiting, stomach pain, oliguria, hypothermia, decreased blood pressure, tachycardia, dyspnea, tinnitus, drowsiness, delirium, unconsciousness, acute agranulocytosis, hemorrhagic syndrome, acute or acute convulsions, paralysis of respiratory muscles.
Treatment: symptomatic. There is no specific antidote for sodium metamizole. In the conditions of the medical institution - carrying out forced diuresis, hemodialysis, in the development of convulsive syndrome - intravenous injection of diazepam and high-speed barbiturates.
Storage conditions
In a place protected from light, out of reach of children, at a temperature not exceeding 25 ° C
Terms leave through pharmacies
In retseptu
Dosage form
solution for injection and infusions
fairfavf19f20f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f19f25f19f19f19f19f19f19f19f19f25f19f19f25f Sky Factory, Russia
Analgin ampoules 500mg / ml, 2 ml, 10 pcs (metamizol sodium) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Analgin ampoules 500mg / ml, 2 ml, 10 pcs - Sale. PayPal accept. Free shipping florida. Fast international shipping.
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