Aminoplasmal E 15 infusion solution 500 ml (24 g nitrogen / l) vials 10 pcs. (amino acids for parenteral POWER, Prochye Preparations Myneral)

Release form

Solution for infusion

Pharmacological action

Aminoplasmal E - supplementing the deficiency of amino acids and electrolytes.

Included in the composition of 20 amino acids (in the form of levorotatory isomers) are well absorbed and provide protein synthesis substrate. Normalizes electrolyte balance.

Calorie content of the solution is 400 kcal / l (1675 kJ / l), osmolarity - 1030 mOsm / l.

Indications

Parenteral Nutrition.

Prevention and treatment of protein deficiency due to severe loss and / or increased protein demand: pre- and postoperative period (in cases when normal eating is impossible or undesirable), injuries (moderate and severe), burns, damage to the esophagus or stomach with caustic substances, stenosis of various sections of the gastrointestinal tract, diffuse peritonitis, osteomyelitis, hypoparathyroidism, malabsorption syndrome, inflammatory diseases of the gastrointestinal tract, prolonged diarrhea, vomiting, anorexia , cachexia in cancer, prolonged fever, poisoning, stroke, coma, nephrosis, amyloidosis.

Contraindications

Severe circulatory disorders with a threat to life (for example, in shock), amino acid metabolism disorders, severe liver dysfunction, hyperhydration, renal failure with increased rates of residual nitrogen, acidosis, hyperkalemia, hyponatremia.

Use during pregnancy and lactation

Since the safety of using Aminoplasmal during pregnancy and lactation has not been studied, the drug should not be used during pregnancy, especially in the first trimester, except in situations in which the potential benefit to the mother exceeds possible risk to the fetus.

Special instructions

To ensure a more complete assimilation of amino acids, the introduction of high-calorie non-protein solutions (carbohydrate solutions, fat emulsions) should be carried out simultaneously with the introduction of Aminoplasmal E. The ratio of non-protein calories to the introduced nitrogen should be 100-200 kcal / g nitrogen.

Composition

Active ingredients:

isoleucine 5.1 g

leucine 8.9 g

lysine hydrochloride 7 g

methionine 3.8 g

phenylalanine 5.1 g

threonine 4.1 g

trip 4.8 g

arginine 9.2 g

histidine 5.2 g

glycine 7.9 g

alanine 13.7 g

proline 8.9 g

aspartic acid 1.3 g

asparagine monohydrate 3.72 g

acetylcysteine 0.68 g

glutamic acid 4.6 g

ornithine hydrochloride 3.2 g

serine 2.4 g

tyrosine 0.3 g

acetyl tyrosine 1, 23 g

sodium acetate trihydrate 3.95 g

potassium acetate 2.45 g

magnesium acetate tetrahydrate 0.56 g

sodium dihydrogen phosphate dihydrate 1.4 g

malic acid 1.01 g

Dosage and Administration

Intravenous drip. The infusion rate is up to 1 ml / kg / h.

The dose is set individually (depending on the condition of the patient), as a rule: 10% (5%) solution - up to 20 (40) ml / kg / day for the prevention and treatment of minor protein deficiency - 8–16 (16–32) ml / kg / day, to ensure the body's need for proteins during pregnancy and after operations - 16–20 (32–40) ml / kg / day.

Side effects

Too fast administration of the drug can lead to symptoms such as chills, nausea, and vomiting.

In such cases, the drug should be discontinued and resumed later at a lower rate of infusion.

Drug Interactions

It is not recommended to introduce any other drugs into the Aminoplasmal 10% E solution, it is preferable to include them in standard solutions of carbohydrates and electrolytes.

However, in cases where the use of a mixture of drugs with Aminoplasmal 10% E is necessary, it is recommended that they be checked for compatibility before use.

Overdose

Symptoms: Growing kidney failure.

Treatment: symptomatic with mandatory reduction of the infusion rate or termination.

Storage Conditions

In a dark place at a temperature not exceeding 25 ° C.

Shelf life

3 years

Active ingredient

Amino acids for parenteral nutrition, Miscellaneous preparat Mineral

dosage form

infusion solution

Prescription

On The values ​​

Adult prescribed by a doctor, children doctor intended

B.Broun Melzungen AG, Germany



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