Ambrobene solution for oral administration and inhalation 7.5 mg / ml vial. 100ml

Structure

1 ml of solution for oral administration and inhalation contains:

Active ingredient: ambroxol hydrochloride 7.5 mg

Excipients: potassium sorbate, hydrochloric acid, purified water.

pharmachologic effect

Ambrobene belongs to chemical preparations that have an expectorant and phlegm-thinning effect.

The drug has a therapeutic effect in diseases with cough and difficult sputum discharge.

The main active ingredient is ambroxol.

Ambrobene also has an antioxidant effect: it neutralizes and removes damaging molecules called free radicals from the body.

The drug reduces the viscosity of phlegm and facilitates its outflow from the bronchi.

Ambrobene acts as follows:

the drug stimulates the production of enzymes in the bronchial mucosa, which break down the bonds between the substances that make up the phlegm

activates the formation of surfactant (a mixture of active substances that prevent adhesion of the alveoli of the lungs)

activates the function of the cilia of the bronchial mucosa, preventing them from sticking together.

Indications

For the treatment of chronic and acute respiratory diseases, in which there is sputum and its discharge from the respiratory tract is impaired: pneumonia, bronchitis with difficulty in sputum discharge, bronchial asthma, bronchiectasis.

Contraindications

individual intolerance to any component of the drug

peptic ulcer of the stomach and duodenum

epilepsy and convulsive syndrome

functional failure of the liver and kidneys

secretion of sputum in large quantities and impaired bronchial motility due to immobile cilia (due to the threat of sputum stagnation in the bronchi).

Side effects

From the immune system: infrequently - hypersensitivity reaction

frequency not established - anaphylactic reactions, incl.

rash, itching, urticaria, angioedema, anaphylactic shock.

From the nervous system: often - a violation of taste.

From the gastrointestinal tract: often - nausea

infrequently - dryness of the mucous membrane of the mouth and throat, vomiting, dyspepsia, abdominal pain, diarrhea.

Interaction

With the simultaneous use of ambroxol and antitussives, due to suppression of the cough reflex, secretion stagnation may occur.

Therefore, such combinations should be selected with care.

With the combined administration of ambroxol and the antibiotics amoxicillin, cefuroxime, erythromycin and doxycycline, the concentration of the latter in sputum and bronchial secretions increases.

The introduction of ambroxol (pH 5) should not be combined with the introduction of other solutions with a pH of more than 6.3, since the difference between the pH values ��of the solutions can lead to precipitation of the ambroxol base.

How to take, course of administration and dosage

The duration of treatment is selected individually, depending on the course of the disease.

It is not recommended to take Ambrobene without a doctor's prescription for more than 4-5 days.

The mucolytic effect of the drug is manifested when a large amount of liquid is taken.

Therefore, during treatment, it is recommended to drink plenty of fluids.

Inside, after meals, adding to water, juice or tea using the supplied measuring cup.

Children: up to 2 years old - 1 ml of the drug 2 times a day (15 mg of ambroxol per day)

from 2 to 6 years old - 1 ml of the drug 3 times a day (22.5 mg of ambroxol per day)

from 6 to 12 years old - 2 ml of the drug 2-3 times a day (30-45 mg of ambroxol per day).

Adults and children over 12 years of age: in the first 2-3 days of treatment - 4 ml of the drug 3 times a day (90 mg of Ambroxol per day).

If therapy is ineffective, adults can increase the dose to 8 ml of the drug 2 times a day (120 mg of ambroxol per day).

On the following days, you should take 4 ml of the drug 2 times a day (60 mg of ambroxol per day).

Inhalation

When using the drug Ambrobene in the form of inhalation, you can use any modern equipment (except for steam inhalers).

Before inhalation, pre

Name ENG

AMBROBENE

Clinical and pharmacological group

Mucolytic and expectorant drug

ATX code

Ambroxol

Dosage

7.5mg / ml x 100ml

Structure

1 ml of solution for oral administration and inhalation contains: Active ingredient: Ambroxol hydrochloride 7.5 mg

Excipients: potassium sorbate, hydrochloric acid, purified water.

Indications

Acute and chronic diseases of the respiratory tract, accompanied by a violation of the formation and discharge of sputum.

INN / Active ingredient

Ambroxol

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 5 years

Contraindications

Hypersensitivity to ambroxol or one of the excipients

pregnancy (I trimester).

Specifications

Category

Thinning phlegm

,

Expectorants

Scope of the drug

Respiratory system

Release form

Syrup

Manufacturer country

Germany

Package quantity, pcs

one

Scope of application

Virology

Minimum age from

From birth

Way of introduction

Through the mouth

,

Through the respiratory tract

Vacation conditions

Without recipe

Volume, ml.

100 ml

Brand name

Ambrobene

Components

measuring glass

The amount of the dosage form in the primary package

100 ml

Primary packaging type

Dropper bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Expectorant mucolytic agent

Anatomical and therapeutic characteristics

R05CB06 Ambroxol

Dosage form

Solution for oral administration and inhalation

The target audience

Children

Expiration date in days

1825

Dosage (volume) of the substance in the preparation

ambroxol hydrochloride 7.5 mg

Package weight, g

one hundred

Mode of application

:

The duration of treatment is selected individually, depending on the course of the disease. It is not recommended to take Ambrobene without a doctor's prescription for more than 4-5 days. < br> The mucolytic effect of the drug is manifested when taking a large amount of liquid. Therefore, during treatment, it is recommended to drink plenty of fluids. < br> Inside, after meals, adding to water, juice or tea using the supplied measuring cup. < br> Children: under 2 years old - 1 ml of the drug 2 times a day (15 mg of ambroxol a day) from 2 to 6 years - 1 ml of the drug 3 times a day (22.5 mg of ambroxol per day) from 6 to 12 years old - 2 ml of the drug 2-3 times a day (30-45 mg of ambroxol per day). < br> Adults and children over 12 years of age: in the first 2-3 days of treatment - 4 ml of the drug 3 times a day (90 mg of Ambroxol per day).If therapy is ineffective, adults can increase the dose to 8 ml of the drug 2 times a day (120 mg ambroxol per day). On the following days, you should take 4 ml of the drug 2 times a day (60 mg of Ambroxol per day).

Information on technical characteristics, delivery set, country of manufacture