Almagel A suspension of 170 ml (Alheldrat, benzocaine, magnesium hydroxide)

Latin name

ALMAGELВ® A

Release form

Suspension for oral administration.

Packaging

Bottle 170 ml.

Pharmacological action

Almagel® A - drug, which is a balanced combination of algeldrate (aluminum hydroxide), magnesium hydroxide and benzocaine. It neutralizes free hydrochloric acid in the stomach, reduces the activity of pepsin, which leads to a decrease in the digesting activity of gastric juice. It has an enveloping, adsorbing effect. Protects the gastric mucosa by stimulating the synthesis of prostaglandins (cytoprotective effect). This protects the mucous membrane from inflammatory and erosive hemorrhagic lesions as a result of the use of irritating and ulcerogenic agents, such as ethyl alcohol and non-steroidal anti-inflammatory drugs (e.g. indomethacin, diclofenac, aspirin, acetylsalicylic acid, corticosteroid drugs). The therapeutic effect after taking the drug occurs in 3-5 minutes. The duration of action depends on the rate of gastric emptying. When taken on an empty stomach, the action lasts up to 60 minutes. When taken an hour after a meal, the antacid effect can last up to 3 hours. Does not cause secondary hypersecretion of gastric juice.

Benzocaine has a local anesthetic effect in the presence of severe pain.

Indications

Acute gastritis, chronic gastritis with increased and normal secretory function of the stomach (in the exacerbation phase), acute duodenitis, enteritis, colitis

, peptic ulcer of the stomach and duodenum (in the exacerbation phase)

gastroesophageal reflux oesophagus, hernia , duodenogastric reflux

symptomatic gastrointestinal ulcers of various genesis of erosion of the mucous membrane of the upper gastrointestinal tract

acute pancreatitis, exacerbation of chronic pancreatitis

heartburn and epigastric pain after errors in the diet, excessive consumption of ethanol, nicotine, coffee, medication, irritating the gastric mucosa. Prevention of gastric and duodenal disorders

reduction of irritating and ulcerogenic effects associated with taking medications that irritate the gastric mucosa.

Contraindications

Hypersensitivity to the active or any auxiliary substance that is part of the drug.

Severe renal failure (due to the danger of developing hypermagnesemia and aluminum intoxication).

Not prescribed for children, as there is a risk of methemoglobinemia

Pregnancy and lactation

Use during pregnancy and lactation

AlmagelВ® A is not prescribed during pregnancy and lactation, since it contains benzocaine.

Composition

5 ml (one scoop) suspension contain: Active ingredients: Aluminum hydroxide gel -2 18 g

in terms of Al2О3 -218 mg

Magnesium hydroxide infusion - 350 mg

in terms of MgO - 75 mg

Benzocaine - 109 mg

Excipients:

Hydrogen peroxide solution 30% - 0.41 mg, sorbitol - 801 15 mg, hyetellose - 10.90 mg, methyl parahydroxybenzoate - 10.90 mg, propyl parahydroxybenzoate - 1.363 mg, butyl parahydroxybenzoate - 1.333 mg, sodium saccharinate dihydrate - 0.818 mg, propylene glycol - 327.00 mg, macrogol 4000 - 218.00 mg oil - 1.635 mg, ethanol 96% - 98.10 mg, purified water to 5 ml

10 ml (1 sachet) suspensions contain:

Active ingredients:

Aluminum guide hydroxide gel - 4.36 g

in terms of Al2O3 - 436 mg

Magnesium hydroxide infusion - 700 mg

in terms of MgO - 150 mg

Benzocaine - 218 mg

Excipients:

Hydrogen peroxide solution 30% - 0.82 mg, sorbitol - 1602.300 mg, hyetellose - 21.80 mg, methyl parahydroxybenzoate - 21.80 mg, propyl parahydroxybenzoate - 2.726 mg, butyl parahydroxybenzoate - 2.726 mg, sodium saccharine glycol dihydrate - 654.00 mg, macrogol 4000 - 436.00 mg, lemon oil - 3.27 mg, ethanol 96% - 196.20 mg, purified water to 10 ml.

Dosage and administration of

Treatment of

Adults

5-10 ml (1-2 scoops) or 1 sachet 3-4 times a day 10-15 minutes before meals.

The maximum duration of treatment is 7 days, then they switch to treatment with Almagel®

. It is not recommended to take fluids within 15 minutes after taking the drug.

Before use, the suspension must be thoroughly homogenized by shaking the bottle or kneading and shaking the bag.

Side effects

Almagel® A may cause constipation that disappears after a dose reduction.

In rare cases, nausea, vomiting, stomach spasm, change in taste, allergic reactions and hypermagnesemia are observed.

With prolonged use of the drug in patients with renal failure and undergoing dialysis, changes in mood and mental activity are possible

With prolonged use of high doses of the drug along with phosphorus deficiency in food, osteomalacia may occur.

Drug Interaction

May absorb some medicines, thus reducing their absorption, so when taken with other medicines, they must be taken 1-2 hours before or after taking Almagel® A.

Almagel® A reduces the acidity of gastric juice, and this can affect the effect of a large number of medicines at the same time.

Almagel® Reduces the effect of histamine H2 receptor blockers (cimetidine, ranitidine, famotidine), cardiac glycosides, iron salts, lithium, quinidine, mexiletine, phenothiazine preparations, tetracycline antibiotics, ciprofloxacin, isoniazid and ketoconazole.

At the same time intake of intestinal preparations the raised pH of gastric juice can lead to the accelerated disturbance of the yus membrane and cause irritation of the stomach and duodenum. Almagel can affect the results of some laboratory and functional tests and tests: it reduces the level of gastric secretion in determining its acidity, changes the results of tests using technetium (TC ), such as bone scintigraphy and some tests for esophageal examination, increases serum phosphorus levels, values serum and urine pH.

Overdose

With a single dose overdose, there are no signs of overdose other than constipation, flatulence, a metallic taste.

With prolonged administration of high doses, nephrocalcinosis, the appearance of severe constipation, light drowsiness, hypermagnesemia are possible. Signs of metabolic alkalosis can also be observed: mood or mental activity change, numbness or muscle pain, irritability and rapid fatigue, slowing of breathing, unpleasant taste sensations.

In these cases, it is necessary to take immediate steps to quickly remove the drug from the body (induction of vomiting, intake of activated carbon).

Storage conditions

At a temperature not exceeding 25C.

Do not freeze! Keep out of the reach of children!

Expiration

2 Year

Deystvuyuschee substances

Alheldrat, benzocaine, magnesium hydroxide

Dosage form

dosage form

su oral suspension

Bax er, Bulgaria



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