Almagel A suspension. d / internal approx. fl. 170ml # 1

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SKU
FL10203115
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Category

Ulcer and gastritis

,

Antacids

Scope of the drug

Gastrointestinal tract

Release form

Oral suspension

Manufacturer country

Bulgaria

Package quantity, pcs

one

Description

Release form, composition and packaging

Suspension for oral administration is white or almost white, with a characteristic lemon odor

during storage, a layer of a transparent liquid may form on the surface with vigorous shaking of the bottle, the homogeneity of the suspension is restored

5 ml (1 measuring spoon)

algeldrat (aluminum hydroxide gel) 2.18 g,

which corresponds to the content of aluminum oxide 218 mg

magnesium hydroxide paste 350 mg,

which corresponds to the content of magnesium oxide 75 mg

benzocaine 109 mg

sorbitol - 801.15 mg, hyetellose - 15.26 mg, methyl parahydroxybenzoate - 10.9 mg, propyl parahydroxybenzoate - 1.363 mg, butyl parahydroxybenzoate - 1.363 mg, sodium saccharinate dihydrate - 0.818 mg, lemon oil - 1.635 mg, purified ethanol 96% - 98.1 mg, purified water ml

170 ml - bottles (1) complete with a dosing spoon - cardboard packs.

pharmachologic effect

The instruction was approved by the Pharmacological Committee of the Ministry of Health of Russia 03/02/2001

Almagel A neutralizes free hydrochloric acid in the stomach, which leads to a decrease in the digestive activity of gastric juice.

Does not cause secondary hypersecretion of gastric juice.

Has a local anesthetic, adsorbing and enveloping effect, reduces the effect of damaging factors on the mucous membrane

The therapeutic effect after taking the drug occurs in 3-5 minutes and lasts an average of 70 minutes

Almagel A provides long-term local neutralization of continuously secreted gastric juice and reduces the content of hydrochloric acid in it to the optimal limits for treatment. Aluminum hydroxide inhibits the secretion of pepsin, neutralizes hydrochloric acid, forming aluminum chloride, which is converted into alkaline aluminum salts in the alkaline medium of the intestine. Magnesium hydroxide also neutralizes hydrochloric acid, converting to magnesium chloride. This counteracts the constipation-causing effect of aluminum hydroxide. Magnesium hydroxide and magnesium chloride are resorbed to an insignificant extent and practically do not affect the concentration of magnesium ions in the blood

Benzocaine has an effective and long-lasting local analgesic effect in severe pain. Sorbitol, which is part of the drug, promotes increased bile secretion and exhibits a mild laxative effect, complementing the effect of magnesium hydroxide. Almagel A does not sharply increase the pH of the stomach contents, buffers its value from 4.0-4.5 to 3.5-3.8 (physiological value) between doses. The drug forms a protective layer, providing a uniform distribution of active substances on the gastric mucosa and has a long-term local effect without the subsequent formation of carbon dioxide in the stomach, which, in turn, causes flatulence, a feeling of heaviness in the epigastric region and a secondary increase in the secretion of hydrochloric acid

According to the classification of Hodge and Sterner, the drug, when administered orally, is classified as a mildly toxic agent and has no embryotoxic, teratogenic or mutagenic effects.

In some cases, increased tendon reflexes were noted in newborns whose mothers took the drug for a long time.

In addition, in newborns there is a risk of developing hypermagnesemia, especially in a state of dehydration, therefore, prolonged use of the drug for pregnant women and newborns is not recommended.

Pharmacokinetics

Almagel A is a non-absorbable drug.

If the correct dosage regimen and the duration of treatment are observed, it is practically not resorbed in the gastrointestinal tract and has a long-term uniform effect without disturbing the electrolyte balance and without creating a risk of alkalosis or other metabolic disorders.

It does not irritate the urinary system and, with prolonged use, does not cause alkalosis and the formation of calculi in the urinary tract.

Indications for use

peptic ulcer of the stomach and duodenum in the phase

Name ENG

ALMAGEL A

Clinical and pharmacological group

Antacid in combination with a local anesthetic

ATX code

Antacids, other combinations

Dosage

2.18mg / 5ml + 109mg / 5ml + 350mg / 5ml x 170ml

Structure

5 ml (one scoop) suspension contains: Active ingredients: Aluminum hydroxide gel -2.18 g in terms of Al2O3 -218 mg Magnesium hydroxide infusion - 350 mg in terms of MgO - 75 mg Benzocaine - 109 mg Excipients: Hydrogen peroxide solution 30% - 0.41 mg, sorbitol - 801.15 mg, hyetellose - 10.90 mg, methyl parahydroxybenzoate - 10.90 mg, propyl parahydroxybenzoate - 1.363 mg, butyl parahydroxybenzoate - 1.363 mg, sodium saccharinate dihydrate - 0.818 mg, propylene glycol - 327, 00 mg, macrogol 4000 - 218.00 mg, lemon oil - 1.635 mg, ethanol 96% - 98.10 mg, purified water to 5 ml 10 ml (1 sachet) suspensions contain: Active ingredients: Aluminum hydroxide gel - 4.36 g in terms of Al2Рћ3 - 436 mg Magnesium hydroxide infusion - 700 mg in terms of MgO - 150 mg Benzocaine - 218 mg Excipients:Hydrogen peroxide solution 30% - 0.82 mg, sorbitol - 1602.300 mg, hyetellose - 21.80 mg, methyl parahydroxybenzoate - 21.80 mg, propyl parahydroxybenzoate - 2.726 mg, butyl parahydroxybenzoate - 2.726 mg, sodium saccharinate dihydrate - 1.636 mg, propylene glycol 654.00 mg, macrogol 4000 - 436.00 mg, lemon oil - 3.27 mg, ethanol 96% - 196.20 mg, purified water up to 10 ml.

Indications

Acute gastritis

chronic gastritis with increased and normal gastric secretory function (in the acute phase)

acute duodenitis, enteritis, colitis

peptic ulcer of the stomach and duodenum (in the acute phase)

hernia of the esophageal opening of the diaphragm, gastroesophageal reflux, reflux esophagitis, duodenogastric reflux

symptomatic gastrointestinal ulcers of various origins

erosion of the mucous membrane of the upper gastrointestinal tract

acute pancreatitis, exacerbation of chronic pancreatitis

heartburn and epigastric pain after errors in nutrition, excessive use of ethanol, nicotine, coffee, taking medications that irritate the gastric mucosa.

Prevention of gastric and duodenal disorders

reduction of irritating and ulcerogenic effects associated with taking medications that irritate the gastric mucosa.

Contraindications

Hypersensitivity to the active substance or to any auxiliary substance that is part of the drug.

Severe form of renal failure (due to the risk of developing hypermagnesemia and aluminum intoxication).

It is not prescribed for children, since there is a risk of developing methemoglobinemia

Pregnancy and lactation.

INN / Active ingredient

Algeldrat + benzocaine + magnesium hydroxide

Storage conditions and periods

In a dark place at a temperature not exceeding 25 degrees.

(do not freeze).

Expiration date: 2 years

Specifications

Category

Ulcer and gastritis

,

Antacids

Scope of the drug

Gastrointestinal tract

Release form

Oral suspension

Manufacturer country

Bulgaria

Package quantity, pcs

one

Minimum age from

1 month

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Almagel

Components

measuring spoon

The amount of the dosage form in the primary package

170 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antacid + local anesthetic

Anatomical and therapeutic characteristics

A02AB10 Aluminum preparations in combination

Dosage form

Suspension for oral administration

Expiration date in days

730

Package weight, g

230

Mode of application

:

Inside.

As prescribed by a doctor, 1-3 dosage (teaspoons) spoons, depending on the severity of the case, 3-4 times / day half an hour before meals and in the evening before bedtime.

In children, the drug is used strictly according to the doctor's prescription: children under 10 years of age are prescribed 1/3 of the dose for adults, and for children from 10 to 15 years of age - 1/2 dose for adults. For diseases accompanied by nausea, vomiting and pain in stomach, treatment begins with Almagel A, and after the disappearance of the listed symptoms, they switch to Almagel. Shake the bottle before taking.

Dosage (volume) of the substance in the preparation

:

algeldrat (aluminum hydroxide gel) 2.18 g, which corresponds to the content of aluminum oxide 218 mg, magnesium hydroxide paste 350 mg, which corresponds to the content of magnesium oxide 75 mg, benzocaine 109 mg

Information on technical characteristics, delivery set, country of manufacture

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