Akriderm GENTA ointment for plank beds. approx. tube 15g

Release form, composition and packaging

Ointment for external use 0.05% + 0.1% translucent, white or almost white.

100 g

betamethasone dipropionate in terms of 100% substance 0.064 g,

- which is equivalent to betamethasone 0.05 g

gentamicin sulfate in terms of gentamicin 0.1 g

propyl parahydroxybenzoate (nipazole) - 0.05 g, liquid paraffin (vaseline oil) - 5 g, isopropyl palmitate - 1 g, petroleum jelly - up to 100 g.

15 g - aluminum tubes (1) - cardboard packs.

30 g - aluminum tubes (1) - cardboard packs.

pharmachologic effect

Anti-inflammatory, anti-allergic, antipruritic, antibacterial agent.

Betamethasone dipropionate is a synthetic glucocorticosteroid (GCS) that has anti-inflammatory, anti-allergic, antipruritic and vasoconstrictor effects. When applied topically, it narrows blood vessels, relieves itching, reduces the release of inflammatory mediators (from eosinophils and mast cells), interleukins-1 and -2, gamma-interferon (from lymphocytes and macrophages), inhibits the activity of hyaluronidase and reduces the permeability of the vascular wall. Interacts with specific receptors in the cytoplasm of the cell, stimulates the synthesis of mRNA, inducing the formation of proteins, incl. lipocortin mediating cellular effects. Lipocortin inhibits phospholipase A2, blocks the release of arachidonic acid and the biosynthesis of endoperoxides, prostaglandins, leukotrienes (which contribute to the development of inflammation, allergies and other pathological processes).

Gentamicin is a broad-spectrum antibiotic of the aminoglycoside group.

It has a bactericidal effect and provides a highly effective local treatment of primary and secondary bacterial skin infections.

Active against gram-negative bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae

gram-positive bacteria: Streptococcus spp.

(sensitive strains of group A hemolytic streptococcus), Staphylococcus aureus (coagulase-positive, coagulase-negative strains and some strains that produce penicillinase).

Pharmacokinetics

With external use of the drug in therapeutic doses, the transdermal absorption of active substances into the blood is very insignificant.

The use of occlusive dressings increases the absorption of betamethasone and gentamicin, which may lead to an increased risk of systemic side effects.

Indications for use

- dermatitis (simple and allergic), especially secondarily infected

- eczema (atopic, children's, coin-like)

- atopic dermatitis (diffuse neurodermatitis)

- simple chronic lichen (limited neurodermatitis)

- solar dermatitis

- exfoliative dermatitis

- radiation dermatitis

- diaper rash

- psoriasis

- itching.

Contraindications for use

- tuberculosis of the skin

- vaccination

- viral skin infections

- perioral dermatitis

- rosacea

- cutaneous manifestations of syphilis

- post-vaccination skin reactions

- children under 2 years old

- hypersensitivity to betamethasone, gentamicin, or to any of the excipients that make up the drug.

Dosage regimen

Adults

The ointment is applied in a thin layer to the affected area of ��the skin and surrounding tissues 2 times / day (morning and evening), rubbing lightly in a circular motion.

On areas of the skin with a thicker epidermis and in places from which the drug is easily removed (palms and feet), the ointment should be applied more often.

The duration of treatment depends on the effectiveness and tolerability of therapy and is usually no more than 2-4 weeks.

Children

Children are allowed to prescribe the drug from 2 years old only on strict indications and under the supervision of a doctor.

Due to the fact that in children, the area of ��the skin is larger in relation to body weight, as well as

Name ENG

AKRIDERM GENTA

Clinical and pharmacological group

Drug with antibacterial and anti-inflammatory action for external use

ATX code

Betamethasone in combination with antibiotics

Dosage

0.05% + 0.1% x 15g

Structure

1 gram contains 0.64 mg of betamethasone dipropionate (equivalent to 0.5 mg of betamethasone) and gentamicin sulfate - 1 mg.

Indications

Dermatitis (simple and allergic), especially secondarily infected, eczema (atopic, children's, coin-like), atopic dermatitis (diffuse neurodermatitis), simple chronic lichen (limited neurodermatitis), solar dermatitis, exfoliative dermatitis, radiation dermatitis, diaper rash, psoriasis, pruritus.

Contraindications

Hypersensitivity to any of the components of the drug, skin tuberculosis, skin manifestations of syphilis, chickenpox, herpes simplex, post-vaccination skin reactions, open wounds, lactation and children under 1 year of age

additionally for Akriderm: trophic ulcers of the leg, rosacea, acne vulgaris

additionally for the drug Akriderm GK: in the treatment of external otitis media perforation of the tympanic membrane

additionally for Akriderm SK: perioral dermatitis.

Storage conditions and periods

At a temperature of 15-25 degrees.

Expiration date: 2 years

INN / Active ingredient

gentamicin (as sulfate), betamethasone

Specifications

Category

Psoriasis

Scope of the drug

Dermatology

Release form

Ointment

Manufacturer country

Russia

Package quantity, pcs

one

Scope of application

Allergology

Way of introduction

On the skin

Vacation conditions

Without recipe

Brand name

Akrikhin

The amount of the dosage form in the primary package

15 g

Primary packaging type

Tuba

Type of consumer packaging

Pack of cardboard

Anatomical and therapeutic characteristics

D07CC01 Betamethasone, in combination with antibiotics

Dosage form

Ointment for external use

The target audience

Adult

Expiration date in days

730

Package weight, g

twenty

Mode of application

:

The preparation Akriderm GENTA is applied in a thin layer on the inflamed surface twice a day, rubbing lightly.

In milder cases, a single use is sufficient.

The duration of treatment is determined individually and depends on the nosological form and severity of the disease and is usually 1-2 (rarely 4 weeks).

Pharmaco-therapeutic group

:

Topical glucocorticosteroid + antibiotic aminoglycoside

Dosage (volume) of the substance in the preparation

:

betamethasone dipropionate 0.064 g, which is equivalent to betamethasone 0.05 g, gentamicin sulfate in terms of gentamicin 0.1 g

Information on technical characteristics, delivery set, country of manufacture