Akriderm GENTA cream d / pl. approx. 0.05% + 0.1% tube 15g

Release form, composition and packaging

Cream for external use 0.05% + 0.1% white or almost white.

100 g

betamethasone dipropionate in terms of 100% substance 0.064 g,

- which is equivalent to betamethasone 0.05 g

gentamicin sulfate in terms of gentamicin 0.1 g

methyl parahydroxybenzoate - 0.2 g, propylene glycol - 21.7 g, liquid paraffin - 20 g, macrogol cetostearate - 1.3 g, cetostearyl alcohol [cetyl alcohol 60%, stearyl alcohol 40%] - 5.7 mg, disodium edetate - 0.5 g, sodium hydrogen phosphate - 0.1 g, potassium dihydrogen phosphate - 0.9 g, purified water - up to 100 g.

15 g - aluminum tubes (1) - cardboard packs.

30 g - aluminum tubes (1) - cardboard packs.

pharmachologic effect

Combined preparation for external use with anti-inflammatory, anti-allergic and antibacterial effects.

Betamethasone dipropionate - GCS, has anti-inflammatory, anti-allergic, anti-exudative and antipruritic effects. It inhibits the accumulation of leukocytes, the release of lysosomal enzymes and inflammatory mediators in the inflammation focus, inhibits phagocytosis, reduces vascular tissue permeability, and prevents the formation of inflammatory edema.

Gentamicin is a broad-spectrum antibiotic from the aminoglycoside group.

It has a bactericidal effect against pathogens of primary and secondary bacterial skin infections.

Active against gram-negative bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae

gram-positive bacteria: Streptococcus spp.

(sensitive strains of group A beta and alpha hemolytic streptococcus), Staphylococcus spp.

(coagulase-positive, coagulase-negative and some strains producing penicillinase).

Inactive against anaerobes, fungi and viruses.

Pharmacokinetics

Data on the pharmacokinetics of Akriderm Genta are not provided.

Indications for use

- dermatitis (simple and allergic), especially secondarily infected

- eczema (atopic, children's, coin-like)

- atopic dermatitis (diffuse neurodermatitis)

- simple chronic lichen (limited neurodermatitis)

- solar dermatitis

- exfoliative dermatitis

- radiation dermatitis

- diaper rash

- psoriasis

- itching.

Contraindications for use

- tuberculosis of the skin

- cutaneous manifestations of syphilis

- chickenpox

- herpes simplex

- post-vaccination skin reactions

- open wounds

- lactation period (breastfeeding)

- children's age up to 1 year

- hypersensitivity to drug components.

Dosage regimen

The drug is used externally.

The cream is applied in a thin layer to the affected area of ��the skin 2 times / day (morning and evening).

The frequency of use of the drug is established based on the severity of the disease.

In mild cases, it is sufficient to apply the cream 1 time / day

with more severe lesions, more frequent use is possible.

The duration of treatment depends on the effectiveness and tolerability of therapy and is 2-4 weeks.

In the absence of clinical improvement, it is necessary to clarify the diagnosis.

Overdose

Acute overdose is unlikely, however, with excessive or prolonged use of the drug, chronic overdose is possible, accompanied by signs of hypercortisolism: hyperglycemia, glucosuria, reversible suppression of the adrenal cortex function, manifestations of Cushing's syndrome.

Treatment: Appropriate symptomatic treatment is indicated.

In case of chronic toxic effects, gradual withdrawal of the drug is recommended.

Side effect

Local reactions: with local application of corticosteroids, burning, irritation, dry skin, folliculitis, hypertrichosis, acne-like spills may occur

Name ENG

AKRIDERM GENTA

Clinical and pharmacological group

Drug with antibacterial and anti-inflammatory action for external use

ATX code

Betamethasone in combination with antibiotics

Dosage

0.05% + 0.1% x 15g

Structure

1 gram of cream contains 0.64 mg of betamethasone dipropionate (equivalent to 0.5 mg of betamethasone) and gentamicin sulfate - 1 mg.

Indications

Dermatitis (simple and allergic), especially secondarily infected, eczema (atopic, children's, coin-like), atopic dermatitis (diffuse neurodermatitis), simple chronic lichen (limited neurodermatitis), solar dermatitis, exfoliative dermatitis, radiation dermatitis, diaper rash, psoriasis, pruritus.

Storage conditions and periods

At a temperature of 15-25 degrees.

Expiration date: 2 years

Contraindications

Hypersensitivity to any of the components of the drug, skin tuberculosis, skin manifestations of syphilis, chickenpox, herpes simplex, post-vaccination skin reactions, open wounds, lactation and children under 1 year of age

additionally for Akriderm: trophic ulcers of the leg, rosacea, acne vulgaris

additionally for the drug Akriderm GK: in the treatment of external otitis media perforation of the tympanic membrane

additionally for Akriderm SK: perioral dermatitis.

INN / Active ingredient

gentamicin (as sulfate), betamethasone

Specifications

Category

Psoriasis

Scope of the drug

Dermatology

Release form

Cream

Manufacturer country

Russia

Package quantity, pcs

one

Way of introduction

On the skin

Vacation conditions

Without recipe

Brand name

Akrikhin

The amount of the dosage form in the primary package

15 g

Primary packaging type

Tuba

Type of consumer packaging

Pack of cardboard

Anatomical and therapeutic characteristics

D07CC01 Betamethasone, in combination with antibiotics

Dosage form

Cream for external use

The target audience

Adult

Expiration date in days

730

Package weight, g

15

Mode of application

:

The preparation Akriderm GENTA is applied in a thin layer on the inflamed surface twice a day, rubbing lightly.

In milder cases, a single use is sufficient.

The duration of treatment is determined individually and depends on the nosological form and severity of the disease and is usually 1-2 (rarely 4 weeks).

Pharmaco-therapeutic group

:

Topical glucocorticosteroid + antibiotic aminoglycoside

Information on technical characteristics, delivery set, country of manufacture