Acyclovir Sandoz cream d / nar. approx. 5% tube 5

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In stock
SKU
FL1020746
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Dosage:

5% x 2g

5% x 5g

Scope of the drug

Leather

Release form

Cream

Manufacturer country

Germany

Package quantity, pcs

one

Minimum age from

3 years old

Description

Release form, composition and packaging

Cream for external use, white or almost white, homogeneous.

100 g

acyclovir 5.0 g

macrogol and fatty acid ester (arlaton 983S) - 5.0 g, dimethicone 350 - 0.3 g, cetyl alcohol - 1.5 g, white petrolatum - 9.0 g, liquid paraffin - 5.0 g, propylene glycol - 15.0 g, purified water - 59.2 g.

2 g - aluminum tubes (1) - cardboard packs.

5 g - aluminum tubes (1) - cardboard packs.

5 g - aluminum tubes (4) - cardboard packs.

pharmachologic effect

Antiviral drug for external use.

Acyclovir is active against Herpes simplex types 1 and 2, Varicella zoster virus, Epstein-Barr virus and cytomegalovirus.

Thymidine kinase of cells infected with a virus through a series of consecutive reactions actively converts acyclovir to mono-, di- and acyclovir triphosphate.

The latter interacts with viral DNA polymerase and is embedded in DNA, which is synthesized for new viruses.

Thus, defective" viral DNA is formed, which leads to suppression of replication of new generations of viruses.

Pharmacokinetics

Suction

When used topically, it is practically not absorbed through intact skin, it is not detected in blood and urine.

When applied to affected skin, absorption is moderate.

Withdrawal

It is excreted by the kidneys (up to 9.4% of the daily dose).

In patients with normal renal function, the concentration of acyclovir in the blood serum is up to 0.28 Ојg / ml.

Pharmacokinetics in special clinical situations

In patients with chronic renal failure, the concentration of acyclovir in the blood serum is up to 0.78 Ојg / ml.

Indications for use

- skin infections caused by the Herpes simplex virus types 1 and 2, including genital herpes and herpes of the lips

- shingles

- chickenpox.

Contraindications for use

- hypersensitivity to acyclovir and other components of the drug

The drug should be prescribed with caution during pregnancy, lactation, dehydration, renal failure.

Dosage regimen

Outwardly.

The drug is applied 5 times / day (every 4 hours) with a thin layer on the affected and adjacent areas of the skin.

The cream is applied either with a cotton swab or with clean hands to avoid additional infection of the affected areas.

The therapy should be continued until a crust forms on the vesicles, or until they completely heal.

The duration of therapy is on average 5 days and should not exceed 10 days.

Overdose

Data on overdose of the drug Acyclovir Hexal were not provided.

Side effect

Local reactions: hyperemia, dryness, peeling of the skin

burning, inflammation upon contact with mucous membranes.

Development of allergic dermatitis is possible.

Drug interactions

When applied externally, no interactions with other drugs have been identified.

An increase in the effect is noted with the simultaneous appointment of immunostimulants.

Application during pregnancy and lactation

The drug should be prescribed with caution during pregnancy and lactation (breastfeeding).

There have been no adequate and well-controlled clinical studies of the safety of the drug during pregnancy.

Use is indicated only in cases where the intended benefit to the mother outweighs the potential risk to the fetus.

During the period of treatment, it is necessary to resolve the issue of stopping breastfeeding.

special instructions

To achieve the maximum therapeutic effect, it is necessary to start using the drug as soon as possible after the onset of infection (at the first signs of the disease - burning, itching, tingling, feeling of tension and redness).

The cream is not recommended to be applied to the mucous membranes of the mouth and eyes, because

development of pronounced local inflammation is possible.

When treating genital

Name ENG

ACICLOVIR SANDOZ

Clinical and pharmacological group

Antiviral drug for external use

ATX code

Aciclovir

Dosage

5% x 5g

Structure

100 g of cream contain: active substance: acyclovir - 5.0 g

excipients: propylene glycol - 8.0 g

liquid paraffin (liquid paraffin) - 12.0 g

cetyl alcohol - 6.0 g

macrogol 6 cetostearyl ether - 1.5 g

macrogol 25 cetostearyl ether - 1.5 g

methyl parahydroxybenzoate (methylparaben, nipagin) - 0.15 g

propyl parahydroxybenzoate (propylparaben, nipazole) - 0.05 g

purified water - up to 100.0 g.

Indications

Skin infections caused by Herpes simplex virus types 1 and 2, including genital herpes and herpes of the lips

shingles

chickenpox.

INN / Active ingredient

acyclovir

Contraindications

hypersensitivity to acyclovir and other components of the drug

The drug should be prescribed with caution during pregnancy, lactation, dehydration, renal failure.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 4 years

Specifications

Scope of the drug

Leather

Release form

Cream

Manufacturer country

Germany

Package quantity, pcs

one

Minimum age from

3 years old

Way of introduction

On the skin

Vacation conditions

Without recipe

Brand name

Sandoz

The amount of the dosage form in the primary package

5 g

Primary packaging type

Tuba

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antiviral agent

Anatomical and therapeutic characteristics

D06BB03 Acyclovir

Dosage form

Cream for external use

The target audience

Children

Dosage (volume) of the substance in the preparation

acyclovir 5 g

Expiration date in days

1460

Package weight, g

5

Category

:

Antibiotics

,

Antiseptics and disinfectants

,

Disinfectants

Mode of application

:

Acyclovir cream is applied to the affected surface 5 times / day (after 4 hours).

The duration of treatment is 5-10 days.

Information on technical characteristics, delivery set, country of manufacture "

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